Multiple Sclerosis News

FDA Grants ‘Breakthrough Therapy’ Designation to Genentechā€™s Ocrelizumab for PPMS

Genentech recently announced that the U.S. Food and Drug Administration (FDA) granted its investigational medicine ocrelizumab, a potential treatment forĀ primary progressive multiple sclerosis (PPMS),Ā Breakthrough Therapy DesignationĀ based on positiveĀ Phase 3 clinical trial results showing thatĀ ocrelizumab significantly reduced disability progression and other disease activity markers compared toĀ placebo. The FDA designation is…

Might Chocolate Ease Multiple Sclerosis Fatigue?

A research team from Oxford Brookes UniversityĀ is being given aĀ Ā£70,000 ($107,000) grant to analyze whether dark chocolate can help ease symptoms of multiple sclerosis (MS). The Multiple Sclerosis Society (MS Society) will fund the study. The goal of the project, according to aĀ press release,Ā is to investigate if a…

Could Remyelination Be Achieved in MS Using an Anti-Inflammatory Treatment?

In a recent study entitled ā€œPromotion of Remyelination by Sulfasalazine in a Transgenic Zebrafish Model of Demyelination,ā€ researchers investigated whetherĀ sulfasalazine treatment, an anti-inflammatory and immune-modulating drug, could promote remyelination of axons in an organism model of demyelination diseases such as multiple sclerosis (MS). The study was published in the…

Generic Form of Glatiramer Acetate Has Equivalent Gene Expression Profile as Teva’s Copaxone

In a recent study entitled ā€œEquivalent Gene Expression Profiles between Glatopaā„¢ and CopaxoneĀ®,ā€ authors determined potential differences in treatment responses by investigating the gene expression profile of two approved treatments for relapsing forms of multiple sclerosis ā€“ Copaxone and Glatopa. Both of these MS therapies are glatiramer…

The Future of Stem Cell Therapy for Multiple Sclerosis Patients Relies on Clinical Trial Participation

Among the different therapeuticĀ approaches being explored for treating MS,Ā adult stem cell therapy continues to beĀ one of the most discussed and anticipatedĀ in the MS community. ā€œStem cellsā€ ā€” the common term for undifferentiated, self-renewing proliferating cells ā€”Ā are currently being investigated for their ability to treatĀ patients in a wide range of disease…

Does Sun Exposure in Early Years Delay MS Onset?

Exposure to sunlight may delay the development of multiple sclerosis (MS), according to a new study from researchers in Denmark. The work, titled “Association between age at onset of multiple sclerosis and vitamin D levelā€“related factors,” appeared October 7, 2015 in the journal Neurology.

MS Care: A Hot Topic at #ECTRIMS2015

Three ā€œHot Topic Sessionsā€ on multiple sclerosis will take place this afternoon (17:00 ā€“ 17:45 h, GMT + 1h) at the 31st Congress of the European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS), currently being held in Barcelona, Spain, October 7 ā€“ 10. The first session is entitled…

Could Genentechā€™s Ocrelizumab Become the First Effective Primary Progressive MS Therapy?

Genentech, a leading biotechnology company and member of the Roche Group, recently announced promising results on a pivotal Phase III clinical trial (ORATORIO) assessing its investigational therapyĀ ocrelizumab as a treatmentĀ for patients with primary progressive multiple sclerosis (PPMS). Multiple sclerosis (MS) is a chronic, progressive neurodegenerative disorder that results from…

Brain-specific B Cells’ Reactivity Determines Glatiramer Acetate Therapy Success in MS Patients

In a new study entitled ā€œThe brain antigen-specific B cell response correlates with glatiramer acetate responsiveness in relapsing-remitting multiple sclerosis patients,ā€Ā a team of scientists discovered that differences in response toĀ glatiramer acetate therapy among multiple sclerosis (MS) patients is potentially dependent on the presence of reactive brain-specific B…

Clinical Benefit of Relapsing-Remitting Multiple Sclerosis Therapies Highlighted in Review

A review study recently published in the journal Cochrane Database of Systematic Review (CDSR) focused on the clinical benefit of different therapiesĀ available for relapsing-remitting multiple sclerosis (RRMS). The study is entitled ā€œImmunomodulators and immunosuppressants for relapsing-remitting multiple sclerosis: a network meta-analysisā€ and was led…

Fingolimod (Gilenya) Found to Be an Effective Multiple Sclerosis Therapy for Up to Three Years of Treatment

An encouraging newĀ analysis reveals that fingolimod isĀ an effective multiple sclerosis (MS) therapy forĀ a treatment period of up to three years. The results were presented at the Annual Meeting of the Consortium of MS Centers. MS is a chronic, progressive neurodegenerative disorder that is the result ofĀ anĀ attack onĀ the central nervous system…