April 24, 2024 News by Andrea Lobo, PhD Foralumab found to ease fatigue in SPMS patients in access program Fully 70% of patients with nonactive secondary progressive multiple sclerosis (SPMS) who received foralumab nasal spray in an expanded access program (EAP) experienced a lessening in fatigue levels after six months of treatment. That’s according to early findings from the EAP ā a program that enables patients with serious…
February 28, 2024 News by Margarida Maia, PhD Balance training helps both in easing fatigue, restoring balance: Small trial Both balance and endurance training can help to ease fatigue in people with multiple sclerosis (MS) ā but if problems with balance are a concern, then balance training would be the best choice as it targets both fatigue and balance, a small study found. The study, āFatigue may…
February 21, 2024 News by Margarida Maia, PhD Melatonin at night may help with morning balance, strength in MS Taking melatonin before bedtime may help balance and muscle strength in people living with multiple sclerosis (MS), according to a study from Tunisia. Those benefits are in addition toĀ making for more restful sleep. While the findings come from a small number of patients, they suggest melatonin supplements may…
February 6, 2024 News by Patricia Inacio, PhD Fatigue predicts worse health-related quality of life in RRMS Fatigue is a significant predictor of worse health-related quality of life in adults with relapsing-remitting multiple sclerosis (RRMS), a study reports. High levels of fatigue were significantlyĀ linked with worse physical and mental health, including cognitive impairments, depression, and anxiety. The findings suggest…
January 10, 2024 News by Margarida Maia, PhD Foralumab nasal spray shown to ease fatigue in nonactive SPMS Six of eight patients with nonactive secondary progressive multiple sclerosis (SPMS) being treated with foralumab nasal spray ā all part of an intermediate-size expanded access program (EAP) allowing the therapy’s use ā have experienced reductions in their fatigue levels. That’s according to treatment developer Tiziana Life Sciences,…
December 27, 2023 News by Andrea Lobo, PhD SMS text messages may help MS patients self-manage fatigue: Study Sending SMS text messages to people with multiple sclerosis (MS) ā with tips for fatigue self-management and to regularly check in on them ā may be a feasible, acceptable, and engaging tool to help these patients manage disease-related fatigue, according to a pilot study. The findings also showed some…
December 4, 2023 News by Patricia Inacio, PhD Aerobic cycling eases fatigue and pain of MS, if intensity kept up Adhering to an aerobic exercise program of moderate to intense cycling for 12 weeks significantly eased pain and fatigue in people with multiple sclerosis (MS), allowing them to be more active in daily life, a small pilot clinical trial found. Results were similar for patients in the trial’s forced…
November 14, 2023 News by Steve Bryson, PhD Less restrictive low-fat diet seen to lessen fatigue in MS: Pilot study Adhering to a low-fat diet for three months was found to significantly ease fatigue among people with multiple sclerosis (MS), according to data from a pilot clinical trial. The diet, which restricted total fat intake to less than 20% of calories per day, had a good adherence. Unlike other…
October 31, 2023 News by Patricia Inacio, PhD Better sleep linked to quality of life, mental health in children with MS In children with pediatric-onset multiple sclerosis (POMS), poor sleep quality is linked to fatigue, depression, and worse quality of life, a study has found. While no significant differences in sleep measures were identified between children and adolescents with MS compared with those without the neurodegenerative condition, sleep can have…
September 22, 2023 News by Patricia Inacio, PhD Fatigue not eased with DMTs in people with MS: Study Using disease-modifying therapies (DMTs) doesn’t reduce fatigue levels in people with multiple sclerosis (MS), a study in Norway suggests. Anxiety and depression were both associated with fatigue, suggesting “there are other underlying causes of fatigue than focal inflammation, on which DMTs have an effect,” the study’s researchers wrote…
August 10, 2023 News by Lindsey Shapiro, PhD Physical activity may reduce fatigue in people with RRMS: Trial More daily physical activity, better physical condition, and lower disability were all associated with less fatigue for people with relapsing-remitting multiple sclerosis (RRMS), according to a clinical trial in Finland. āThe findings are interesting and support previous studies very well,” Marko Luostarinen, a doctoral researcher at the University of…
August 1, 2023 News by Andrea Lobo, PhD Web-based wellness program improves life quality, lowers fatigue A web-based wellness intervention program that educated multiple sclerosis (MS) patients on dietary plans, stress management, sleep, and exercise recommendations significantly improved their fatigue and quality of life, according to data from a clinical study. The study, āEvaluation of a web-based program for the adoption of wellness behaviors…
July 28, 2023 Columns by John Connor What started as a simple problem turned into a complex kerfuffle Long ago, I acquired a pair of speakers for my laptop. In fact, theyāve survived many, many iterations of the things. Laptops become outdated quickly, their inbuilt fans fail, or, as in my latest version, the installed RAM is only 8 gigabytes. I’ve been made aware that RAM, or random-access…
July 14, 2023 Columns by Ed Tobias Bottoms up: Why I’m drinking more water because of my MS I’m drinking again, more than I have in years. It’s not the hard stuff, though; not even beer or wine. It’s just plain water. That may sound crazy for someone like me who has bladder problems due to multiple sclerosis (MS). For many of us with MS, we…
May 4, 2023 Columns by Benjamin Hofmeister Fatigue from MS is hard to both explain and understand Everyone’s multiple sclerosis (MS) is unique to them. The different disease types, lesion loads, and lesion locations are a few reasons why our symptoms are so variable. We with MS all live in the same neighborhood, just in different houses. If there were such a thing as…
April 14, 2023 News by Marisa Wexler, MS Abnormal perceptions may help cause heat sensitivity in MS: Study Abnormal perceptions of discomfort and fatigue likely play a role in causing increased heat and cold sensitivity to extreme temperatures among people with multiple sclerosis (MS), a new study shows. However, the results suggest that MS does not generally affect how the body regulates its own temperature. “Our findings…
April 3, 2023 News by Marisa Wexler, MS MS sexual issues associated with fatigue, depression: Study Issues with sexual performance and satisfaction are common with multiple sclerosis (MS), and show significant associations with measures of quality of life, a study shows. Sexual problems tend to be more pronounced among patients with severe fatigue and depression, data suggest. These findings highlight areas where healthcare providers can…
February 21, 2023 News by Margarida Maia, PhD Phase 2 trial to determine if low-dose ketamine eases MS fatigue A Phase 2 clinical trial evaluatingĀ whether a low dose of ketamine can ease fatigue in people with multiple sclerosis (MS) is enrolling patients at Johns Hopkins University in Baltimore. The study, called INKLING-MS (NCT05378100), is recruiting up to 110 patients, ages 18-65,Ā who have been complaining of fatigue as…
January 10, 2023 News by Joana Vindeirinho, PhD Lifestyle Changes to Increase Physical Activity Improved MS Fatigue A behavioral intervention that teaches people with multiple sclerosis (MS) strategies for becoming physically active significantly improved patient-reported measures of fatigue over a year, but had no effect on other self-reported disease measures, according to new data from a Phase 3 trial. Earlier results had shown that the approach,…
December 14, 2022 News by Marisa Wexler, MS Bright Light Therapy Shows Promise for Easing MS Fatigue in Small Trial Daily exposure to 30 minutes of bright light for two weeks led to clinically significant reductions in fatigue scores among people with multiple sclerosis (MS) in a small clinical trial. “The findings from our study represent a promising non-drug therapeutic approach,” Stefan Seidel, PhD, co-author of the study…
December 12, 2022 News by Joana Vindeirinho, PhD Noninvasive Brain Stimulation Can Ease Some MS Symptoms: Review Noninvasive brain stimulation (NIBS) may be able to reduce fatigue, spasticity, and pain, and improve quality of life in patients with multiple sclerosis (MS), a new meta-analysis reports. The review assessed several NIBS interventions targeting different brain regions. The results suggest that these techniques can have immediate effects…
November 14, 2022 News by Marisa Wexler, MS Dietary Changes Can Help Ease Fatigue, Improve Quality of Life Dietary interventions may help ease fatigue and improve quality of life in people with multiple sclerosis (MS), although it doesn’t seem to impact disability progression, according to a new analysis. Researchers emphasized that it’s difficult to draw solid conclusions about the impact of diet in MS because there haven’t…
November 14, 2022 News by Patricia Inacio, PhD Sexual Dysfunction Linked to MS Fatigue, Psychological Symptoms The severity of sexual dysfunction doesn’t seem to be associated with MRI measures of disease activity in multiple sclerosis (MS), but it was significantly linked with depression, anxiety, and fatigue, a small study found. The findings highlight the complex nature of sexual dysfunction in MS and āunderscore the importance…
September 16, 2022 News by Lindsey Shapiro, PhD Stem Cell Transplant for MS Eases Fatigue, Improves Life Quality Autologous hematopoietic stem cell transplant (aHSCT) ā commonly called stem cell therapy ā lessens fatigue and improves quality of life in people with highly active relapsing multiple sclerosis (MS), according to a small study in Lithuania. These gains in the physical and social domains of quality of life…
September 7, 2022 News by Margarida Maia, PhD High-intensity Resistance Training May Help MS Patients With Fatigue Three months of once-weekly sessions of high-intensity resistance training ā consisting of strength exercises followed by a short recovery between sets ā effectively eased fatigue in multiple sclerosis (MS) patients experiencing low energy and tiredness, a trial in Sweden shows. This intervention also lessened feelings of depression and anxiety,…
August 25, 2022 News by Marisa Wexler, MS Aquatic Exercise Found to Ease Fatigue, Improve Balance in MS Aquatic exercise therapy can help to ease fatigue and improve balance in people with multiple sclerosis (MS), without notable side effects, according to a review of published studies. These findings have important implications for MS patients, as fatigue is among the main symptoms of the disease and…
August 17, 2022 News by Lindsey Shapiro, PhD Early Factors Identified That Predict Health-related Quality of Life Researchers have identified early factors that can affect the trajectory of a patient’s long-term health-related quality of life (HRQoL) after a multiple sclerosis diagnosis. These factors include older age, worse physical impairment, and more severe fatigue at diagnosis, which were predictive of worse long-term physical HRQoL. In addition,…
July 20, 2022 Columns by Beth Ullah A Big Step Forward: Using Public Transportation With MS As anyone with chronic illness knows, leaving the house requires planning. Thereās much more to think about than what’s visible, especially if you’re relying on public transport. In the days preceding last week’s appointment with my multiple sclerosis (MS) nurse, I was contemplating just how long it’d been since…
July 14, 2022 News by Lindsey Shapiro, PhD Yoga Course Found to Ease Fatigue, Anxiety in MS Patients in Study A six-week program combining yoga and group discussions about resilience led to significant reductions in fatigue and anxiety, and improvements in well-being, for people with multiple sclerosis (MS), according to results from a pilot study. Researchers noted that the program, known asĀ LoveYourBrain Yoga, “may improve a range of…
July 13, 2022 by BioNews Staff Expert Voices: Exercising effectively, safely with multiple sclerosis In this installment of our āExpert Voicesā series, Multiple Sclerosis News Today asked Mandy Rohrig to answer some of your questions about how to make exercise effective and safe for people with multiple sclerosis (MS). Mandy Rohrig graduated from Nebraska Wesleyan University with a bachelor of science in…