News MS Trial to Improve Physical Activity, Lower Fatigue via Telehealth Is Enrolling Participants MS Trial to Improve Physical Activity, Lower Fatigue via Telehealth Is Enrolling Participants by Patricia Silva, PhD | February 16, 2016 Share this article: Share article via email Copy article link A new Ā multiple sclerosis (MS)Ā clinical trial being led byĀ Case Western Reserve UniversityĀ investigatorsĀ is now recruiting 215 individuals, across 10 U.S.Ā states to assess whether the fatigue management and physical activity interventions often provided by rehabilitation centers can effectivelyĀ be offered byĀ telehealth, throughĀ a series of teleconferences and phone interviews. AnĀ National MS SocietyĀ research grant is supportingĀ the workĀ of the study’sĀ lead investigator,Ā Dr. Matthew Plow,Ā the society announced inĀ itsĀ press release. Many people report fatigue as a main disability ofĀ MS. It can be chronic and severe, interfering with patients’Ā ability to maintain a job or to engage in leisure activities. Reduced physical activity, in turn, leads to a poorerĀ physical condition and increased fatigue levels. Dr. Plow willĀ determineĀ if methods of fatigue management and increasing physical activity, often conductedĀ by on-site by medical professionals or occupational and physical therapists, can be conducted remotely. The proposed study (NCT01572714),Ā investigators report, will be the largest randomized controlled trial to examine the effects of a lifestyle physical activity intervention in people with MS. Participants must be ages 18 toĀ 65, with a confirmed MS diagnosis and the ability to walk 25 feet with or without a cane. People who exercise more than 90 minutes a week, who are pregnant, who have any metabolic or cardiopulmonary disease that puts them at risk in aĀ home exercise program, or who have had four or more falls in the past six months are not eligible to take part inĀ the trial. Patients will be randomly assigned to one of three activity groups, with all receiving weekly support via phone conferences: Ā an educational program combining fatigue management with physical activity; a physical activity promotion program only, orĀ an educational and social support group. Over the trial’sĀ 24 weeks, changes in physical activity levels will be measured as a primary outcome, whileĀ secondary outcomes will assess fatigue levels and quality of life. Eligible participants must live in one of the following states: Wisconsin, West Virginia, Pennsylvania, Ohio, New York, New Jersey, Michigan, Kentucky, Indiana or Illinois. Information regardingĀ participation criteria for this trial is available by writing toĀ Meghan Golding atĀ [email protected] or by calling her at 216-368-0643. More information is also available through a National MS Society brochure. MS is an unpredictable and potentially disabling disease that affects the central nervous system (CNS) by disrupting the flow of information within the brain, and between the brain and otherĀ body regions. Symptoms can vary from numbness and tingling to paralysis or blindness. MS is generally diagnosed between 20 and 50 years of age, and women are twice asĀ likely to develop the condition asĀ men. Print This Page About the Author Patricia Silva, PhD PatrĆcia holds a PhD in medical microbiology and infectious diseases from the Leiden University Medical Center, Netherlands, and completed a postdoctoral research fellowship at the Instituto de Medicina Molecular, Lisbon, Portugal. Her work in academia was mainly focused on molecular biology and the genetic traits of infectious agents such as viruses and parasites. PatrĆcia earned several travel awards to present her work at international scientific meetings. She is a published author of several peer-reviewed science articles. Tags clinical trial, fatigue, National MS Society, physical activity, rehabilitation
April 19, 2024 News by Lindsey Shapiro, PhD AAN 2024: Long-term data support early Kesimpta start in relapsing MS
April 18, 2024 Columns by Benjamin Hofmeister Learning how to write a ‘SOAP’ note feels different after an MS diagnosis
April 18, 2024 News by Marisa Wexler, MS AAN 2024: Sustained myelin, nerve cell gains with long-term CNM-Au8