Last week’s hot topic on multiple sclerosis was MS Gait Analysis Identifies 2 New and Highly Sensitive Markers of Disability and Fatigue written by Margarida Azevedo.
This article is about researchers analyzing the gait in people with multiple sclerosis (MS) using wearable inertial sensors. They have established two new highly sensitive observer-independent measures of disability that strongly correlate with fatigue and patient-perceived health status. Their article, titled “Disability and Fatigue Can Be Objectively Measured in Multiple Sclerosis,” was published in the journal PLOS ONE.
Researchers concluded: “We established two novel observer-independent measures of disability. E discriminated MS patients according to disability, whereas mROMH was extremely sensitive in measuring motor impairment within patients. If confirmed in larger studies, this sensitivity will be of crucial importance for monitoring disease course and treatment effects in RRMS patients, when changes in the EDSS are small or absent, and in progressive MS patients, when also small and slow changes in the EDSS are the primary outcomes to assess.”