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Could High-Dose Biotin Be Used as a Treatment for Multiple Sclerosis?


High-dose biotin, a B-complex vitamin, has been found to be an effective tool for slowing down multiple sclerosis (MS) in two clinical trials by MedDay Pharmaceuticals. According to a report on, the vitamin also known as vitamin H could be used to treat both relapsing and progressive multiple sclerosis.

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Trials of the vitamin discovered that it helps to strengthen myelin as well as provide energy for neurons. The first trial using 300 mg of high-quality biotin consisted of just 23 MS patients but showed significant improvements, the second test — a double-blind clinical trial — used 154 patients and again showed that biotin was useful in slowing down and improving disability in people living with progressive MS.

The company is now planning its phase 3 clinical trial using a larger study base involving 600 patients from the U.S. and Europe.

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Multiple Sclerosis News Today is strictly a news and information website about the disease. It does not provide medical advice, diagnosis or treatment. This content is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or another qualified health provider with any questions you may have regarding a medical condition. Never disregard professional medical advice or delay in seeking it because of something you have read on this website.

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  1. Bonni says:

    I’ve tried to use Biotin a few times over the last year and it has given me horrible IBS and other digestive problems. I thought it might be the “Hail Mary” for helping to heal lesions, but I’m in the 10% who cannot tolerate the drug. I am hopeful the manufacturers will develop a shot or infusion in the future. For now, I am unable to use Biotin.

  2. Douglas says:

    Having high-quality biotin compounded is very expensive. I’ve seen a few places offering 100mg capsules at an affordable price
    (i.e. Metabiome) but I have no way of knowing the quality of what they are selling.

    • Lesley says:

      I realize this is coming late, but rest assured that the high quality of this brand is assured, and the price is right, at under $40/mo. My own neurologist has this compounded at a reliable pharmacy, and puts his name on it. The phase III trials should come to an end by Sept ’19. This will hopefully show it as a cumulative myelin repair, so don’t expect an overnight miracle. Keep the faith!

  3. Rosanne Costain says:

    I take 30,000 MCG biotin daily and I hope I wi; see an improvement. Still can’t take the sun, my MS “hug” disappeared
    after I had venaplasty on the right side, in fact, I regained most feeling on my right side, stopped “shuffling” my feet, stopped slurring my words, and my brain fog cleared substantially.
    I am 63 years old, if that helps to know. Copaxone did nothing at all for me.

  4. Sandra says:

    Makes me wonder about microwave ovens. Have you seen the vitamins that are killed using these? So many illnesses in my opinion are linked to the nutrients lost during the cooking.

  5. Margaret says:

    Hi Everyone,
    Please be your own advocate! Research, research..I have PPMS and 2 Neurologists..I prefer having more than one option.
    This is a direct note from my Dr. regarding the use of PURE BIOTIN POWDER *pls consult your Dr. or get a second option.
    Hi Donna, I have PPMS. I have 2 Neuro DR’s, I prefer to have 2 options/opinions and it just happens that my primary Neuro Dr. had no clue about the biotin benefits!

    This is a direct note from my Dr. at Kaiser.

    “There is some evidence that high dose biotin (300mg daily) may be beneficial in progressive multiple sclerosis

    There is a challenge in obtaining biotin at this dose because the over the counter dose is between 0.3mg (300mcg) and 10mg

    You can obtain biotin by going to and typing in “biotin powder”
    You may also have to purchase small cooking spoons because 300mg of biotin is roughly 1/16th of a teaspoon

    You can also find 100mg tablet on Amazon from Natural Creations. You would take 3 tablets daily. It is $60 for 90 tablets, so this would end up being $60/month which is more expensive than buying the Powder”

    Here is the direct website:
    Pls read and consult your Dr.
    God Bless!!

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