High Doses of Vitamin D Unlikely to Help MS Patients, But Daily Low Dose Good for All, UK Group Says

High Doses of Vitamin D Unlikely to Help MS Patients, But Daily Low Dose Good for All, UK Group Says

The Multiple Sclerosis Trust announced that the Vitamin D working group, part of the U.K. Scientific Advisory Committee on Nutrition (SACN), has published a 300-page, comprehensive report now recommending that anyone age 4 and older take 10 μg (400 IU) of vitamin D each day  to ensure musculoskeletal health.  The review, “Vitamin D and Health,” was conducted to assess whether the U.K. dietary recommendations, set in 1991, were still appropriate.

People with multiple sclerosis (MS) are not advised to take higher doses to treat the disease because of conflicting evidence regarding vitamin D supplements, the group said in a press release.

According to some neurologists, high doses of vitamin D supplements may be beneficial for MS patients. These  neurologists recommend that patients and their family members take around 100-124 μg (4000-5000 IU) of vitamin D every day (about 10 times the daily recommended dose for the general population), but others do not agree.

Research has shown that low levels of vitamin D are associated with the risk of developing MS, disease relapses, and increased disability. However, no causal role of vitamin D in reducing the risk or severity of MS has been seen. In fact, research studies to date have failed to produce any evidence showing that vitamin D supplements reduce the risk of developing MS or the severity of the condition. Most of these were observational studies and not randomized controlled trials, and produced inconsistent data between MS and vitamin D. Larger studies are ongoing to further investigate the potential benefits of vitamin D in MS. The MS Trust has a factsheet on vitamin D available for patients and others to download.

Vitamin D is essential to maintain muscle and bone health. Vitamin D is present in fish, eggs and fortified cereals, although in limited amounts, not enough to provide all the vitamin D that the body needs. Most of the vitamin D required for healthy muscles and bones is synthesized through sunlight on the skin.

According to Public Health England, most people get enough vitamin D through sunlight on their skin in the spring and summer seasons. During fall and winter, the agency — based on the working group’s findings — also recommends that people take 10 μg vitamin D supplements, and that they eat a healthy, balanced diet throughout the year.


      • Robert,

        The “toxicity” that is fear is hypercalcemia. It can affect your heart and/or your kidneys. The thousands of patients who enjoy a halt to their MS and reversal in many cases, have no issues with this because we omit all calcium from our diets, and drink a lot of liquid to dilute any residual in our blood stream. There will come a point where there are so many of us, the facts can no longer be ignored. This is how things work in our world. We go to the neurologist and ask to be put on the vitamin D protocol. The neurologist says no for fear of a hypercalcemic event. We do it anyway. Next time we WALK back into the office, or our MRI shows amazing regression of disease, and suddenly the neurologist wants to know where they can learn more. It’s unfortunate that this is the slog we have to go through to get this information out…and with all due respect…how much misinformation there is such as the article above, whether intentional or just lacking complete information, but those of us posting here are not trying to stir up trouble. To the contrary we are screaming at the top of our lungs trying to get the message out that you do not have to suffer from this disease…or any autoimmune disease anymore.

      • serema says:

        im not a expert in the topic but i by mistake used around only 20000 unit (my medicin had told 10000)plus calcium mg pills and a bit of sun bathing! omg my muscles were extremely painfoul afterward with a lot of weird bumps on the hip so paniqued that i went to dr and got anti inflammatory drugs. Never understood what was the cause but as soon as i stopped taking ca mg and vit d pills lime candies muscles came back to normal. i believe there is a tolerance level for everyone diffetent with others causing muscle toxicity…

    • Dawn Williams says:

      I’m one of them. Doing things I haven’t done for over 20 years. People can visible notice different (normal) gait

    • Jeff Bowles says:

      I remember a Henry Lahore who left a 2012 review of the Book …The Miraculous results of extremely high doses of the sunshine hormone vitamin d3>>> he gave it a 1 star!! Saying 50,000 IU of d3 was very very dangerous!! even though the average adult can make 20,000 iu of d3 in their skin with just 1/2 hour of summer sunbathing!! HAHAHHA..Henry likes to run around pretending to be an expert …

  1. Linda Neal says:

    The sun makes me incredibly I’ll but the gallons of milk that I have consumed over my lifetime definitely makes up for getting large amounts of that particular vitamin.

  2. Ana Claudia says:

    You couldn’t be more wrong… Only in Brazil about 7,000 patients can show the results of high doses of vitamin D. Not what those studies call “high doses”, but real high doses. I’m on 60,000 IU daily, 8 years of treatment, MS completely inactive, no brain atrophy after starting vitamin D, and lesions remylienating. No side effects from vitamin D whatsoever.

  3. Christian says:

    Studies that associate level of vitamin and severity of disease started in 1986…how long people suffering of ms have to wait for double blind studies? Anyway 4000 iu is the dose that allow you the get in the middle of the range of the laboratory i can’t understand how a so low dose can be dangerous..

  4. Stef says:

    “According to Public Health England, most people get enough vitamin D through sunlight on their skin in the spring and summer seasons. During fall and winter, the agency — based on the working group’s findings — also recommends that people take 10 μg vitamin D supplements, and that they eat a healthy, balanced diet throughout the year.”

    This is a blatant lie. I would like to see where you found this reference. I live in England, I am a scientist and I have a PhD like you. I have also MS and I write about MS research every single day. I am aware bad side effects could be triggered by high doses of Vitamin D but in this article there are massive lies.

    • Ilya Dudkin says:

      Could you describe please the bad side effects of high doses of Vitamin D?I hope taking “horse” doses can just little cure

    • P says:

      Hi Stef,
      Can you point me to some of your research articles please? I have recently been diagnosed and want to read as much as possible.

  5. I followed the patients in Brazil. I have had MS for 10 years, with no symptoms other than increasing lesions on MRI. I decided to see for myself. Please explain to me how those all of those lesions shut down and began shrinking after I began taking 80,000 IU of D, now on 130,000 with no residual side effects. If you are offering patients no more than 10,000 IU, than no…you’re not going to see any benefit…because it is not enough. See Dr. Cicero Coimbra, and the thousands of patients that see success 95% of the time over a 15 year period, then come back and tell us how it’s not working.

  6. Carolyn Richardson says:

    I started on high doses of Vitamin D3 combined with Super K (K2 from Life Extension). I can only say that I now truly believe my MS symptoms are getting resolved, I’m back to where I was before my last relapse. Just been for a full 360% health check, I am normal or above normal on everything except very high on my HDL cholesterol the good cholesterol, but average on total cholesterol. My Blood calcium levels were normal, but getting another test done to check. Now on 110,000 IU of D3 daily not felt this good in years. In the 1930/40’s D3 would have been the recommended course of treatment, all the test have been done a long time ago see PubMed and search for D3. The problem is that a Hormone like D3 can’t be licenced so drug companies can’t make a profit from it.

  7. Karen McGrew says:

    I have secondary progressive ms, and I started taking 6000 IU of vitamin D3 per day, but noticed heart palpitations. You have to balance the amount of magnesium and calcium to the vitamin D3 or you can have that problem, which can be serious. Those three supplements should be taken in equal amounts.

  8. jonas moura de araujo says:

    I am a Doctor from Brazil and treat patients with high doses ( 40.000 a 200.000 UI of vitamina D3 with good results and no problems. patients have your quality of life regained

  9. Dawn Williams says:

    My MS is also gone. Neuro wont believe it yet but GP can see gait, balance and general well being. Neuro said could be Tecfidera. I said no it can’t I haven’t been taking it. Hot flush side effects are making it worse. I took 10,000 IU a day for winter months, 1,000 during summer (I live in Australia lots of sun). Hanging out for MRI to show reduced lesions.

  10. For those of you doing well, congratulations! I had forgotten about this post, but thought I would report back. I’m alive and well and in great shape. Still on doses of well over 100,000. I’ve had 3 MRIs and which still with no activity, shrinking lesions, no disability and no hypercalcemia. I would encourage you to look into the Coimbra protocol. Since my posting a few years ago. We have seen 1000s across the globe return to health and put their autoimmune disease in permanent remission (not a cure) but permanent halting of disease.
    Best wishes.

  11. Jeff Bowles says:

    I personally take 150,000 iu a day just for general health and have no health issues I also take a lot of vitamin k2…with it. to make it safe..( and don’t watch my calcium intake-k2 puts it back in the bones) AS long as your blood calcium is normal your d3 levels could be 10,000!! (vs ref range of 30 to 100) with no toxic effects D3 itself is 100% non toxic only need to watch blood calcium! The more I look into it the more I am thinking that when they changed 25 mg of vitamin d2 into 1 million iu’s of D2 they did it to scare people off of Vit D with the big scary numbers! People n the 1920’s were routinely taking 25 mg a day of vit d2 and the hospitals were empty!! (note d2 is the inferior plant version of d3 which is only about 1/4th to 1/16th as strong/effective as d3) here is a link to a good article on high dose d3 and MS>>>>


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