[jan-hardee]

I guess this thread is a little old (no pun intended), but its exactly what I’ve been looking for.  I am 65, diagnosed in my early 30’s with RRMS and have always been mostly mildly affected by my symptoms.  About 5 years ago, my neurologist suggested I might want to try some of the new drugs to keep symptoms at bay and I agreed.  For about 18 months I took Tecfidera, then switched to Ocrevus infusions shortly after it was approved.  I’ve had three so far with no side effects. It IS  hard to say if it’s doing anything – my symptoms are might have moderately advanced –slightly more noticeable numbness, weakness and balance issues — but nothing extreme.  Recently I moved to another state and went to a new neurologist hoping to get the infusions continued.  I was stunned when he questioned why I was getting them at my age.  He mentioned studies that seemed to indicate they had little effect among elderly patients. I couldn’t really defend their effectiveness since I didn’t know if I was any “better”, but I also didn’t know if my condition might not be worse without them.  (He even questioned whether I was sure I HAD MS and ordered another MRI, which did confirm “fairly extensive disease”.)  I guess my question to the group is has anyone been counseled against getting Ocrevus infusions because of their age affecting efficacy?  I am aware of the impact on the immune system — but isn’t that was the same with Tecfidera and presumably others.  Has anyone had any experience quitting Ocrevus infusions?  If the doctor is right and the drug is having no effect, I worry about what happens when I stop.  Any advice out there?