November 26, 2020November 26, 2020

New $100M Program Aims to Improve Diversity in Clinical Trials

News

A new $100-million program aims to improve the diversity of participants in U.S. clinical trials with the ultimate goal of achieving better health outcomes and parity in care for underserved ... Read more

November 25, 2020November 25, 2020

Tablet-based Video Game Could Help Measure Cognitive Impairment in MS, Study Shows

News

People with multiple sclerosis (MS) may have cognitive defects that cannot be detected using conventional paper-and-pen tests but that can be assessed with computer-based tests, a new study shows. ... Read more

November 25, 2020November 26, 2020

Gut Immune Cells That Travel to Brain May Help Resolve MS Disease Relapses

News

A particular type of gut microbiota-reactive immune cells, called IgA-producing B-cells, travels to the brain of multiple sclerosis (MS) patients during relapses, where they produce anti-inflammatory molecules, a study ... Read more

November 24, 2020November 24, 2020

Tysabri Affects Immune System Beyond Known MS Target, Study Finds

News

Lower levels of pro-inflammatory immune signaling proteins were found in the blood of people with relapsing-remitting multiple sclerosis (RRMS) treated with Tysabri (natalizumab) and were associated with fewer relapses ... Read more

November 24, 2020November 24, 2020

Tecfidera Found in Breast Milk But Levels Appear Safe, Case Study Reports

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Tecfidera (dimethyl fumarate) was detected in the breast milk of two women using the oral therapy to treat their multiple sclerosis, but at concentrations well below the “theoretical threshold ... Read more

November 23, 2020November 23, 2020

ChariotMS to Test Mavenclad in SPMS, PPMS Patients With Little Ability to Walk

News

An upcoming Phase 2 clinical trial, called ChariotMS, will test whether Mavenclad (cladribine) can slow a worsening of hand and arm function in people with progressive multiple sclerosis (MS) ... Read more

November 23, 2020November 23, 2020

Early Use of Ocrevus Best for Slowing PPMS Progression, Long-term Data Show

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Early and continuous use of Ocrevus (ocrelizumab) significantly slows disability progression and delays the time until wheelchair reliance in people with primary progressive multiple sclerosis (PPMS), new Phase 3 data spanning ... Read more

November 20, 2020November 20, 2020

Smartphone Typing Patterns May Be Tool for Monitoring MS Progression, Study Finds

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Typing patterns in daily smartphone use show clinically relevant changes over time in people with multiple sclerosis (MS), but not among healthy individuals, a study shows. Notably, these variations ... Read more

November 20, 2020November 20, 2020

MS Patients With Depression Symptoms Have More Difficulty Multitasking, Study Shows

News

Patients in the early stages of multiple sclerosis with mild to moderate symptoms of depression performed worse on cognitive tests related to multitasking than on those focused on single ... Read more

November 20, 2020November 20, 2020

Autoimmune Registry Releases Comprehensive US List of These Diseases

News

The nonprofit Autoimmune Registry (ARI) has published its first comprehensive list of autoimmune diseases, with information addressing more than 150 disorders, their subtypes, and prevalence in the U.S. This list ... Read more

November 19, 2020November 19, 2020

Progressive MS Focus of EMSP Virtual Meeting Open to All Starting Today

News

Progressive multiple sclerosis (MS) is the focus of the 2020 virtual European Multiple Sclerosis Platform (EMSP) annual meeting that runs though Friday, Nov. 20. Registration is free for the two-day conference. Those ... Read more

November 18, 2020November 18, 2020

Software Platform May Allow for Automated MS Cognitive Testing

News

A software platform, called CogniSoft, allows for automated assessments of cognitive health in people with multiple sclerosis (MS). The platform was described in the study “CogniSoft: A Platform for ... Read more

November 18, 2020November 18, 2020

Disease Progression Differs More Across MS Type Than Sex of Patients, Study Finds

News

Marked differences in disease characteristics are observed between male and female patients with multiple sclerosis (MS) but they are more pronounced when comparing patients across clinical subtypes, a new ... Read more

November 17, 2020November 17, 2020

TEPP-46 Might Worsen MS Rather Than Treat It, Study Suggests

News

Using a small molecule called TEPP-46 to block the non-metabolic function of the enzyme pyruvate kinase M2 (PKM2) in T-helper (Th) immune cells did not lessen disease severity and ... Read more

November 17, 2020November 20, 2020

Scientists Create Oligodendrocytes From Stem Cells in Lab Dish in Just Three Weeks

News

Scientists have created myelin-producing cells, called oligodendrocytes, from pluripotent stem cells derived from patients with multiple sclerosis (MS) and amyotrophic lateral sclerosis (ALS) in just three weeks. They also demonstrated ... Read more

November 16, 2020November 16, 2020

New MS Trust Funding Will Help Improve Patient Support During Pandemic

News

The U.K.’s MS Trust has been awarded £50,000 (about $65,800) from the Coronavirus Community Support Fund — distributed by The National Lottery Community Fund — to further its “Supporting ... Read more

November 16, 2020November 16, 2020

Infection With Toxoplasma Gondii Parasite May Protect Against MS, Study Suggests

News

Toxoplasmosis, an infection by the parasite Toxoplasma gondii, may confer a certain level of protection against multiple sclerosis (MS), according to the results of an Italian study. The study, ... Read more

November 13, 2020November 13, 2020

Start2Cure Foundation Awards Grant to MS Gene Therapy Project

News

Start2Cure Foundation is funding a research project that will investigate the potential of a gene therapy approach to treat multiple sclerosis (MS). MS is an autoimmune disease characterized by the ... Read more