Top 3 Article Selection About Multiple Sclerosis for #CONy16
A new study, published July 17th in the journal Public Library of Science (PLoS) One, evaluated whether imaging techniques can be used to track neurological damage in people with MS. The study also sought to understand whether people with different MS durations have different types of lesions.
Seventeen people with MS or clinically isolated syndrome (an early stage of MS) participated in the study. People were divided into two groups, those with short (less than 60 months) and 11 with long (more than 60 months) disease duration. The researchers used magnetic resonance imaging (MRI) to compare the damage to the nervous system in the study participants.
Results from a small pilot study indicated that high-dose vitamin D supplementation is safe and tolerable in patients with multiple sclerosis (MS), and that it can reduce the presence of autoimmunity-causing immune T cells. Patients are now being recruited for a larger clinical trial. The study, entitled “Safety and immunologic effects of high- vs low-dose cholecalciferol in multiple sclerosis” and was published in the journal Neurology.
Growing scientific evidence indicates that vitamin D plays an important role in MS. Reduced levels of vitamin D, possibly due to low sun exposure, are being investigated as a risk factor for the disease. And the vitamin’s beneficial effect has been observed in mice with experimental autoimmune encephalomyelitis (EAE), an MS-like disease, leading researchers to believe that vitamin D may have a protective effect against autoimmune diseases such as MS.