8. Tecfidera (dimethyl fumarate)
Tecfidera0 (dimethyl fumarate, DMF) is an oral formulation approved by the U.S. Food and Drug Administration (FDA) for relapsing-remitting forms of multiple sclerosis (MS). It has also been studied and used to treat several forms of inflammatory diseases, such sarcoidosis, psoriasis, and necrobiosis lipoidic. Clinical trials of Tecfidera demonstrated its immunomodulatory effects in MS patients, where it was seen to significantly reduce relapse rates and to increase the time of disease progression compared to a placebo. Despite its immunomodulatory properties, it does not induce immune suppression.
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