FDA approved Sanctura (trospium chloride) is used to treat bladder disturbances, which are common in people with MS.

Sanctura for people with MS and overactive bladder, an uncontrollable muscle contraction that leads to symptoms including urinary incontinence, feelings of urination urgency, and frequency of urination acts as an antispasmodic/antimuscarinic drug. Antimuscarinic drugs reduce involuntary contractions of bladder muscles and increases bladder capacity. The drug works by relaxing the bladder muscles and preventing or reducing uninhibited contractions of the bladder muscle. It slows the desire, frequency, and urgency to empty the bladder.

Sanctura comes in two formats: immediate release tablets that are taken in 20 mg doses orally twice a day with water on an empty stomach (at least 1 hour before meals); and extended release tablets that are taken in a 60 mg dose once daily in the morning with water on an empty stomach (at least one hour before meals).

Some side effects include dry mouth or throat, headache, mild constipation, upset stomach, gas, dizziness, drowsiness, or dry eyes.

There are no Sanctura generics available.

Read the latest news about bladder dysfunction and multiple sclerosis.

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