Sani-Supp, a brand of glycerin suppositories, are used for the relief of occasional constipation, They are hyperosmotic laxatives that work by irritating the lining of the intestine and increasing the amount of fluid, drawing water into the bowel from surrounding body tissues. This water helps to soften the stool mass and promote bowel action.

Glycerin suppositories often produce results within 15 minutes to one hour.

Suppositories are for rectal use only and should not be used for longer than one week.

Common side effects that may persist or become bothersome include anal irritation, a burning sensation, diarrhea, gas, nausea, or stomach cramps.

Constipation is the most common symptom of bowel dysfunction in people with multiple sclerosis. MS can interrupt the brain communication that signals that it’s time for a bowel movement. Managing constipation should include a high-fiber diet (from fresh fruits and vegetables, whole grain breads and cereals), combined with high-fluid intake (six to eight glasses of water daily), while trying to maintain an active lifestyle and establishing a bowel schedule. There are a range of laxatives available, most of them sold over-the-counter.

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