March 7, 2024 News by Margarida Maia, PhD ACTRIMS 2024: MRI Paramagnetic rim lesions tied to cognitive decline The presence of paramagnetic rim lesions (PRLs), which represent areas of damage in the brain and spinal cord with chronic active inflammation, may help identify people with multiple sclerosis (MS) who are more likely to have cognitive decline over time. Thatās according to four-year data presented by Hannah Schwartz,…
July 5, 2023 News by Lindsey Shapiro, PhD AI algorithms may predict cognitive decline in MS over coming year Researchers have developed computer algorithms that may be able to predict certain aspects of cognitive change in multiple sclerosis (MS) patients. The prediction models, constructed using data from an electronic, self-administered test of information processing speed given MS patients, might accurately identify those likely to experience cognitive worsening over…
March 28, 2023 News by Andrea Lobo, PhD Sleep disorders in MS women may be factor in cognitive decline: Study Note: This story was updated March 29, 2023, to correct that cognitive function was assessed via questions about memory and three other cognition outcomes. Sleep disorders such as insomnia, sleep apnea, and sleepiness may contribute to self-reported cognitive decline in women with multiple sclerosis (MS), a new study suggests.
May 12, 2022 News by Lindsey Shapiro, PhD Disease Severity, Brain Changes Linked to Cognitive Decline Disease severity, brain volume loss, and brain lesions are able to predict later cognitive declines in people with relapsing-remitting multiple sclerosis (RRMS), a study in China found. The study, āClinical and MRI predictors of cognitive decline in patients with relapsing-remitting multiple sclerosis: a 2-year longitudinal study,ā…
October 13, 2021 by BioNews Staff Expert Voices: Understanding and managing fatigue in multiple sclerosis In this installment of our “Expert Voices” series, Multiple Sclerosis News Today asked Meghan Beier, PhD, a rehabilitation neuropsychologist who teaches skills and techniques to improve patients’ quality of life, to answer some of your questions related to fatigue for people with multiple sclerosis (MS).Ā Beier is a psychologist specializing…
January 27, 2021 News by Marta Figueiredo, PhD Mouse Study Links Cortical Inflammation to Immune Cell Destruction Multiple sclerosis (MS)-associated inflammation in the cerebral cortex ā the outermost layer of the brain that is involved in cognitive function ā prompts the destruction of neural connections by specific immune cells, according to a study in a mouse model of MS. These immune cells targeted dendritic spines (nerve…
January 19, 2021 News by Forest Ray PhD Brain Changes in Relapsing MS Found to Follow Pattern Changes in the amount of grey matter in specific regions of the brain appear to occur early in relapsing multiple sclerosis (MS), while structural changes in white matter happen late in disease progression. These were among the findings of a recent study that tracked the sequence of events in…
February 17, 2020 Columns by Ed Tobias MS News that Caught My Eye Last Week: Report on Ocrevus Use, Cognitive Decline in MS, Gold Nanocrystals and Remyelination Study Ocrevus Use Rises Among New Starters with RRMS, Loses Ground to Other Therapies in PPMS Ocrevus (ocrelizumab) bolted out of the starting gate after it was approved for use in the U.S. about three years ago. However, though its use by people with relapsing forms of multiple sclerosis continues…
February 11, 2020 News by Marisa Wexler, MS Cognitive Decline in MS May Not Be Inevitable or Progressive, 10-year Study Suggests Progressive cognitive decline in patients with multiple sclerosis (MS) may not be as inevitable as previously thought, a study suggests. The study, “A longitudinal study of cognitive function in multiple sclerosis: is decline inevitable?,” was published in theĀ Journal of Neurology. Statistics indicate that some kind…
January 21, 2020 News by Marta Figueiredo, PhD Mayzent Approved in Europe as First Oral Treatment for Active Secondary Progressive MS TheĀ European CommissionĀ has approvedĀ Novartis‘s MayzentĀ (siponimod) as the first oral treatment for adults with active secondary progressive multiple sclerosisĀ (SPMS). Active SPMS is defined by the presence of evident relapses or the detection of inflammatory activity in brain lesions on imaging scans. āAs the only indicated oral therapy proven for…
January 20, 2020 News by Ana Pena PhD Being Bilingual May Help to Delay Cognitive Decline in MS, Study Suggests An ability to speak more than one language may help to protect people with multiple sclerosis (MS) against the cognitive decline caused by the disease, new research suggests. The study, “Multiple sclerosis and bilingualism: Some initial findings,” showed that MS patients who speak two languages (bilingual speakers)…
March 28, 2019 Columns by Tamara Sellman Need to Know: What Exactly Is Cognition? Editor’s note: “Need to Know” is a series inspired by common forum questions and comments from readers. Have a comment or question about MS? Visit our forum. This week’s question is inspired by the forum topic “What do you do to help strengthen your cognitive abilities?” from…
March 4, 2019 Columns by Debi Wilson Is My Memory Loss Due to MS, Aging, or Something Else? My memory is spotty at times. I utter phrases like, āWhat was I looking for?ā more often than I care to admit. I attribute my memory lapses to my multiple sclerosis (MS) brain lesions. But is my assumption accurate? What if it is age-related or…
October 18, 2018 News by Ana Pena PhD #ECTRIMS2018 ā High Vitamin D Levels, Smoking Predict Opposite Effects on Cognition in CIS Patients, Study Suggests High vitamin D levels predict better cognitive function, while smoking is associated with worse long-term cognitive disability in patients with clinically isolated syndrome (CIS), a study suggests. Data from the study was presented by MariannaĀ Cortese, MD, PhD, from the Department of Nutrition, Harvard T.H. Chan…
October 26, 2017 News by Alice MelĆ£o, MSc #MSParis2017 ā Intellectual Enrichment Strategies May Improve Cognitive, Socio-Professional Outcomes of Pediatric-Onset MS Using strategies to promote intellectual enrichment among patients with pediatric-onset multiple sclerosis could be essential to achieving better cognitive, social, and professional performances during adult life, according to researchers at theĀ University of FlorenceĀ in Italy. The finding was theĀ subject of an oral presentation titled, āCognitive reserve is…
July 31, 2017 News by Joana Fernandes, PhD FDA Approves Cognigram Cognitive Assessment Device for Marketing in US The U.S. Food and Drug Administration (FDA) has approved the marketingĀ ofĀ Cognigram, a medical device developed by the cognitive science company CogstateĀ to evaluate a patientās cognitive health. This device may be a…
April 26, 2016 News by Patricia Silva, PhD At-Home ‘Brain Training’ Program for MS Patients Reported to Improve Cognitive Skills by 29% Multiple sclerosis patients using a cognitive remediation computer training program, part ofĀ a controlled trial by researchers fromĀ NYU Langone Medical Center,Ā had greaterĀ improvements in cognitive function than those who used a placebo-training program, according to a presentationĀ at the recentĀ American Academy of NeurologyĀ annual meeting in Vancouver, Canada. Problems in attention, memory,…
July 10, 2015 News by Maureen Newman Risk Assessment Ability Declines With Multiple Sclerosis Disease Severity According To Survey The ability to assess risk may decline as multiple sclerosis disease status progresses over time, as determined by a recent study from University of Alberta in Canada. Principal investigator Esther Fujiwara, PhD, and lead author of the study, Ashley Radomski, used the game of dice task (GDT) to challenge patients…
May 20, 2014 by Patricia Silva, PhD Researchers Explore Role of NAD In Cognitive Decline of Multiple Sclerosis Patients A group of researchers led byĀ Shin-ichiro Imai, MD, PhD, and Liana Roberts Stein, PhD,Ā fromĀ Washington University School of MedicineĀ in St. Louis have been working on pathways to trace cognitive decline in patients with multiple sclerosis (MS). It has been noted in previous research that brain cells derive energy for maintaining…