May 6, 2020 News by Steve Bryson, PhD Immune Cell microRNAs Are Potential MS Biomarkers, Study Suggests Altered levels of molecules important for cell regulation ā called microRNAs ā have been found in specific immune cells isolated from the blood of people with multiple sclerosis (MS), a study reveals. These immune cells, called monocytes, transform into macrophage cells,…
August 6, 2018 News by Jose Marques Lopes, PhD Loss of Specific microRNA Seen to Lessen Disease Severity and Myelin Loss in MS Mouse Model Removing a specific microRNA molecule ā miR-150 ā eased disease severity, inflammation, and loss of myelin in a mouse model of multiple sclerosis (MS), researchers report. Their study, āSilencing miR-150 Ameliorates Experimental Autoimmune Encephalomyelitis,ā was published in the journal Frontiers in Neuroscience. Micro RNAs (miRNAs) are…
March 30, 2017 News by Patricia Inacio, PhD MicroRNA Therapy Restored Myelin Production, Limb Function in MS Mouse Model Using a small RNA molecule belonging to the family of microRNAs (miRs), scientists could restore myelin in nerve cells and improve limb function in mouse models of human multiple sclerosis (MS). The study, āmiR-219 Cooperates with miR-338 in Myelination and Promotes Myelin Repair in the CNS,ā was published in…
January 27, 2017 News by Joana Fernandes, PhD Tiny Molecules in Blood Could Be Biomarkers of MS Progression, Study Says MicroRNAs in the blood could serve as biomarkers to monitor the progression of multiple sclerosis (MS), as well as help identify which mechanisms are at play in each patient, such as inflammation and tissue damage, according to new research. The findings were reported in the study, āAssociation Between Serum…
September 12, 2016 News by Joana Fernandes, PhD Can MS Be Detected by Biomarkers in the Blood? Yes, Study Says MicroRNAs present in the blood show promise as potential biomarkers of multiple sclerosis (MS), a new study suggests. The study, titled āComprehensive Evaluation Of Serum MicroRNAs As Biomarkers In Multiple Sclerosis,ā was published by Keren Regev, MD, and colleagues in the journal Neurology. Human DNA contains…
November 6, 2015 News by Patricia Inacio, PhD New Insights Into Immune Cells’ Behavior in MS May Lead To New Therapeutic Approach In a recent study entitled āMicroRNA expression profiling of human blood monocyte subsets highlights functional differences,ā a team of researchers discovered a pool of 66 microRNAs that underlie differences in phenotype and function of a group of immune cells with key roles in multiple sclerosis. The study was published…
August 31, 2015 News by Patricia Inacio, PhD MS Susceptibility May be Influenced by Female-Specific Variations in MicroRNAs-Coding Genes In a new study entitled āVariants of MicroRNA Genes: Gender-Specific Associations with Multiple Sclerosis Risk and Severity,ā researchersĀ identified variations in genes coding for microRNAs that influence patients’ susceptibility to develop multiple sclerosis, as well as the disease course. Most importantly, these variations were gender specific, identified only…