September 25, 2023 News by Patricia Inacio, PhD Data: Lucid-MS seen to be safe, well tolerated in healthy volunteers FSD Pharmaās Lucid-21-302 ā an oral treatment candidate known as Lucid-MS, for all types of multiple sclerosis (MS) ā was found safe and well tolerated across multiple doses in healthy volunteers, according to interim data from a Phase 1 clinical trial. The newly released data are from the…
April 7, 2023 News by Lindsey Shapiro, PhD OCS-05 neuroprotective therapy for MS shows good safety profile OCS-05, a neuroprotective treatment candidate being developed by Oculis for multiple sclerosis (MS) or other causes of optic nerve inflammation, demonstrated a favorable safety and pharmacological profile in healthy volunteers, according to Phase 1 trial data. AĀ Phase 2 trial (NCT04762017), called ACUITY, is now evaluating OCS-05’s…
March 7, 2023 News by Lindsey Shapiro, PhD ACTRIMS 2023: RRMS treatment may ‘give patients a better choice’ New data from a Phase 2 clinical trial testing vidofludimus calcium, Immunic Therapeuticsā novel oral treatment candidateĀ for relapsing-remitting multiple sclerosis (RRMS), show promising safety and efficacy, according to the company’s chief medical officer. The therapy was found to safely reduce brain lesions and prevent disability progression in…
February 8, 2023 News by Andrea Lobo, PhD Ocrevus can be safe, effective for children with active RRMS: Study Ocrevus (ocrelizumab) is a safe and effective treatment for patients under 18 with highly active relapsing-remitting multiple sclerosis (RRMS), a small study from Turkey suggests. Over about 2.5 years of the treatment, these pediatric patients experienced no relapses or MRI activity, and their disability level also improved, indicating…
February 3, 2023 News by Marisa Wexler, MS Biosimilar Comparable in Safety, Efficacy to Tysabri in Phase 3 Trial PB006, a biosimilar to Biogenās approved treatment Tysabri (natalizumab), showed similar safety and efficacy as the original medication in peopleĀ with relapsing-remitting MS (RRMS), according to data from a Phase 3 clinical trial. “The Antelope trial reported equivalence between [PB006 and Tysabri] treatment across efficacy, safety, and secondary…
June 23, 2022 News by Lindsey Shapiro, PhD aHSCT, Stem Cell Therapy for RRMS, Troubled by Unknowns, Paper Says Autologous hematopoietic stem cell transplant (aHSCT) has shown some promise as a treatment option for highly active relapsing-remitting multiple sclerosis (RRMS), but more clinical evidence is needed to support its use, a team of researchers in the U.K. suggest. “Uncertainty remains as to how aHSCT compares with current…
September 11, 2020 News by Joana Carvalho, PhD #MSVirtual2020 – GeNeuro’s Temelimab Found Safe When Given Alongside Rituximab Temelimab, GeNeuroās investigative treatment for multiple sclerosis (MS), showed a favorable safety profile when given alongside rituximab, according to preclinical safety experiments performed in preparation for the companyās new Phase 2 trial involving patients with relapsing MS. Data from the preclinical experiments, along with details of…