Interesting article/results.
However as perhaps with everything else with MS it’s difficult to apply any test in this area! For a start the tests are subjective! And our fatigue itself is subjective! Yes the majority of us seem too feel it. I most certainly bloody well did and when I was still ambulant it was my biggest disability.
Still subjective tests on a subjective area has the whiff of the rabbit hole! Perhaps I can reach back to symbolic logic and wonder if we’re in the world of the petitio? The conclusion has been assumed in the premises!
I to use Modafinil & never found it helpful in dealing with physical fatigue! However it cut thru what is usually called MS fog – instead of stumbling about in a hazy Holmesian palace of the mind it cut right thru it – it still does! I remember struggling to do a very complex work thang that I was now drowning in – it had never been easy but MS was defeating me. Suddenly I could do it again!
Of course Covid has destroyed that job but the Modafinil still offers me clarity.
Still, I can only subjectively prove it!
How about I open with an ‘Off with their heads’ Queens’s Gambit?