Some of the trials involve a chewing-gum therapy delivery system. The financing will let the company continue developing a patented chewing-gum-delivered therapy for pain and spasticity.
AXIM created MedChew Rx (dronabinol) as a bio-equivalent to AbbVie’s Marinol (dronabinol), an approved treatment for nausea and loss of appetite in cancer patients. A bio-equivalent is a biological therapy that has the same effect as a chemical compound.
The company is in the process of evaluating its gum-delivered THC/CBD (tetrahydrocannabinol/cannabidiol) as a treatment for pain and spasticity in MS.
AbbVie developed Marinola as a gel capsule. A shortcoming of that formulation is that only 90 percent of the drug is metabolized, or converted to a form the body can use. The process occurs in the liver.
The incomplete metabolism causes significant side effects, including impaired thinking.
AXIM designed MedChew Rx to bypass metabolism in the liver as a way of decreasing its side effects.
“This financing enables us to continue to build on the progress we have made with our cannabinoid clinical development program for indications where there are currently no effective treatments,” Dr. George Anastassov, chief executive officer of AXIM, said in a press release. “It is encouraging to see that investors recognize the potential of our robust clinical development pipeline. We are now better positioned to execute on cannabinoid research and commercialization.”
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