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August 17, 2018August 17, 2018

Most MS Patients OK With Intravenous Treatment Conditions, Study Suggests

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Most patients with multiple sclerosis (MS) are satisfied with the conditions of their intravenous therapy (administered directly into the bloodstream) and are very aware of the ... Read more

August 17, 2018August 17, 2018

Healthy Diet May Lower Risk of Developing MS, Study Finds

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People who eat a healthy diet that includes foods such as vegetables, fish, eggs, poultry, and legumes may have a reduced risk of multiple sclerosis (MS), a ... Read more

August 16, 2018August 16, 2018

MS Patients with Anxiety, Depression Symptoms More likely to Report Need for Mental Health Care, Study Shows

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One-third of multiple sclerosis (MS) patients in a Canadian study report a need for mental health care, with symptoms of anxiety and depression — but not ... Read more

August 16, 2018August 16, 2018

Lemtrada Can Lower Number of B-cells Infiltrating Nervous System and Forming Clumps, Animal Study Shows

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Treating mice in a model of multiple sclerosis with Lemtrada (alemtuzumab) prevented the formation of B-cell aggregates in the animals’ central nervous system and disrupted already existing ... Read more

August 15, 2018August 17, 2018

Long-term DMT Use Seen to Lower Likelihood of RRMS Progressing to SPMS in Study

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Long-term treatment with disease-modifying therapies (DMTs) appears to lessen the risk of disease worsening in relapsing-remitting multiple sclerosis (RRMS) patients, an 18-year follow-up study suggests. But these ... Read more

August 14, 2018August 14, 2018

Botox Increases Activity of Brain Regions Involved in Urinary Sensation, New Study Shows

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Botox injections in the bladder muscle increase the activity of brain regions involved in the sensation of urinary urgency in female multiple sclerosis (MS) patients who have ... Read more

August 14, 2018August 14, 2018

Detailed Map of Mouse Nervous System May Help Uncover Origin of Neurological Diseases, Including MS

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Researchers have created a detailed map of the mouse nervous system, including the location of the many diverse cell types in the brain, in the largest ... Read more

August 13, 2018August 13, 2018

Treating Patients’ Perceived Stress and Poor Sleep Important as Both Fuel Depression, Study Reports

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Patients’ perceptions of stress and sleep quality are both linked to their sense of cognitive difficulties and depression, and focusing on these perceptions may be a ... Read more

August 13, 2018August 13, 2018

Kessler Foundation Scientist Receives NMSS Grant to Study Information Processing Speed in MS Patients

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Kessler Foundation scientist Silvana Costa, PhD, was awarded a $477,000 grant from the National Multiple Sclerosis Society (NMSS) to explore the effects of visual, cognitive, and motor deficits ... Read more

August 10, 2018August 10, 2018

Hair Loss Seen in RRMS Patients Using Aubagio Often Temporary and Mild, Study Says

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Hair thinning in relapsing-remitting multiple sclerosis (RRMS) patients using Aubagio is usually mild and temporary, and does not require stopping treatment, a small real-world study reports. The research, ... Read more

August 10, 2018August 16, 2018

TG Therapeutics Reaches Target Enrollment in Phase 3 Trials to Test Ublituximab in Relapsing MS

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TG Therapeutics announced it has reached target enrollment in the ULTIMATE I and II Phase 3 clinical trials assessing the use of ublituximab (TG-1101) to treat ... Read more

August 9, 2018August 13, 2018

Low-dose Botox Treatment Improves Urinary Symptoms in MS Patients, Study Finds

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Results from a Phase 3 clinical trial show that urinary symptoms can be reduced significantly after treatment with low-dose Botox (100 units) in patients with multiple sclerosis ... Read more

August 9, 2018August 14, 2018

MedChew RX Shows Stability and Potential for Effectiveness in Early Tests, Company Reports

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AXIM Biotech announced that tests done on its cannabinoid-based chewing gum — MedChew Rx — showed both product stability and effective release of medicinal molecules, with a high percentage of its pharmaceutical ... Read more

August 8, 2018August 10, 2018

Number, Location, Size of Lesions on MRI Can Predict Progression to MS, Study Shows

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The number, location, and size of lesions can help predict the risk of progression from clinically isolated syndrome (CIS) to multiple sclerosis (MS) within one year, ... Read more

August 8, 2018August 8, 2018

Quanterix’s Simoa Assay May Make Neurofilament Light Chain Useful Blood Biomarker of MS and Its Likely Progression

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Quanterix’s ultra-sensitive Simoa assay has the potential to open new uses for the brain biomarker known as neurofilament light chain, including the possibility to detect early ... Read more

August 7, 2018August 9, 2018

Smoking Increases Relapse Rate in RRMS Patients on Tysabri, Study Suggests

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Smoking increases the relapse rate in patients with relapsing-remitting multiple sclerosis being treated with Tysabri , an observational study suggests. Multiple sclerosis is a multifactorial disease ... Read more

August 7, 2018August 14, 2018

Vitamin D3 Insufficiency Increases MS Susceptibility in a Gene and Sex-dependent Manner

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Vitamin D3 insufficiency increases multiple sclerosis (MS) susceptibility in a gene and sex-dependent manner, a mouse study suggests. The study with that finding, “Sex-Specific Gene-by-Vitamin D Interactions ... Read more

August 6, 2018August 6, 2018

Loss of Specific microRNA Seen to Lessen Disease Severity and Myelin Loss in MS Mouse Model

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Removing a specific microRNA molecule — miR-150 – eased disease severity, inflammation, and loss of myelin in a mouse model of multiple sclerosis (MS), researchers report. ... Read more

August 6, 2018August 6, 2018

Glatect, Alternative to Copaxone, Added to Public Health Plans of 5 Canadian Provinces

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Pendopharm’s Glatect (glatiramer acetate injection), a lower cost alternative to Teva’s Copaxone, has been added to the public health plans of five Canadian provinces for patients with ... Read more

August 3, 2018August 7, 2018

Blood Levels of IgG3 Antibodies May Predict Faster Shift to MS in Clinically Isolated Syndrome Patients, Study Says

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Higher-than-usual levels of specific antibodies in the blood of patients with clinically isolated syndrome (CIS) may predict a faster progression to multiple sclerosis, an Australian study reports. The specific ... Read more

August 3, 2018August 3, 2018

Remington College Opens Partnership with National MS Society by Raising $4,000 to Advance Goals

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Remington College initiated its partnership with the National Multiple Sclerosis Society  by raising more than $4,000 to support the society and its efforts to advance research into ... Read more

August 2, 2018August 6, 2018

Multiple Sclerosis Patients Identify Symptoms that Worsen Quality of Life

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Loss of health-related quality of life is caused mostly by balance problems, muscle stiffness, and depression in people with relapsing-remitting multiple sclerosis (RRMS), and for those with ... Read more

August 2, 2018August 7, 2018

Potential B-cell Targeting Oral MS Treatment, PRN2246, Shows Ability to Reach Brain in Phase 1 Study

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Results from a first-in-human study assessing the safety and early activity of PRN2246 confirmed that the oral compound can reach into the brain and spinal cord. This ... Read more

August 1, 2018August 7, 2018

Pregnancy Worsens Symptoms in MS Patients, Study Finds

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Pregnancy, including successful delivery or miscarriage, worsens symptoms of multiple sclerosis (MS), as well as onset of the disease, a retrospective study shows. Researchers found the same ... Read more

August 1, 2018August 9, 2018

Ozanimod Effectively Lowers Relapse Rates in MS Patients, Data from 2-Year Extension Study Show

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Being treated with ozanimod consistently reduced disease activity in people with relapsing-remitting multiple sclerosis (RRMS), according to results of a two-year extension of a Phase 2 trial. ... Read more

July 31, 2018July 31, 2018

FDA to Review EMD Serono’s New Request for Approval of Cladribine for Treating Relapsing MS

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Seven years after it first denied the request, the U.S. Food and Drug Administration accepted for review EMD Serono’s resubmitted New Drug Application (NDA) for cladribine ... Read more

July 31, 2018August 3, 2018

Researchers Succeed at Generating Oligodendrocytes, Key to Myelin Renewal, in Tissue Created in Lab

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Researchers at Case Western Reserve University School of Medicine have developed a cutting-edge laboratory technique able to turn human stem cells – special cells able to grow into any ... Read more

July 30, 2018August 1, 2018

New Therapy Candidates Could Provide Basis for Regenerative Medicines to Treat MS, Study Suggests

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Therapy candidates that block enzymes responsible for making cholesterol can promote myelin regeneration, a discovery that could lead to new regenerative medicines capable of treating multiple ... Read more

July 30, 2018July 30, 2018

African-Americans Show Better Adherence and Satisfaction with Gilenya Than Injectable DMTs, Phase 4 Study Finds

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African-Americans with relapsing–remitting multiple sclerosis (RRMS) show higher adherence and greater satisfaction when treated with oral Gilenya (fingolimod, by Novartis) than with injectable therapies, according to a ... Read more

July 27, 2018July 31, 2018

Cladribine Added to Interferon-beta Seen to Lower Relapses in Active MS, But Safety Questioned

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Cladribine tablets added to interferon-beta treatment significantly reduced the probability of relapses over 96 weeks in people with active relapsing multiple sclerosis , a Phase 2 ... Read more

July 27, 2018July 30, 2018

Oral DMTs Still Common 1st Therapy for New MS Patients but Ocrevus Having Impact, Market Report Says

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Oral disease-modifying therapies (DMTs) are the most common first choice of treatment for people newly diagnosed with multiple sclerosis (MS) in the United States, an analysis ... Read more

July 26, 2018July 27, 2018

Machine Learning Platform Can Accurately Predict Onset of MS, Maker Says

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IQuity, a data analytics company, announced the launch of an analytics platform that uses machine learning to predict, identify, and monitor chronic disease within large populations ... Read more

July 26, 2018July 31, 2018

Brain Changes in CIS Patients May Be to Blame for Depression, Reduced Quality of Life, Study Suggests

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Changes in the brains of patients with clinically isolated syndrome (CIS), the first clinical presentation of multiple sclerosis (MS), may be partly responsible for depressive symptoms ... Read more

July 25, 2018July 27, 2018

Despite Increased Lesions, No Brain Atrophy Seen in RRMS Patients After Childbirth, Study Reports

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In women with relapsing-remitting multiple sclerosis (RRMS), there is a significant increase in brain lesion volume after pregnancy, but it is not accompanied by a loss of ... Read more

July 25, 2018July 26, 2018

Immune Response Promotes Remyelination in MS Mouse Model

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Activation of the immune response mediated by cells called microglia favors remyelination and myelin repair in multiple sclerosis (MS), according to a new Canadian study using ... Read more

July 24, 2018July 24, 2018

Cerebrospinal Fluid Neurofilament Predicts CIS and RRMS Progression, Study Contends

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Cerebrospinal fluid levels of neurofilament light chain, a protein associated with nerve cell damage, can predict disease progression in people with clinical isolated syndrome (CIS) and ... Read more

July 24, 2018July 25, 2018

Enzyme Key to Myelin Renewal and Nerve Cell Health Possibly Identified in Study

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A better understanding of the processes behind a continual and healthy renewal of myelin — the fatty, protective substance wrapping nerve cell fibers — may now ... Read more

July 23, 2018July 27, 2018

Shorter Washout Period Lessens Relapse Risk When Switching from Tysabri to Gilenya in RRMS, Study Finds

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Shortening the washout period to four weeks when switching from Biogen’s Tysabri to Novartis’ Gilenya is safe and reduces the chances of experiencing a disease flare ... Read more

July 23, 2018July 23, 2018

Hypertension More Common in MS Patients Than General Public, Study Reports

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People with multiple sclerosis are 48 percent more likely to have high blood pressure compared to the general population — and to people with other demyelinating ... Read more

July 20, 2018July 20, 2018

Tysabri Treatment Lessens Sexual Dysfunction in MS Patients, Study Finds

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Treatment with Tysabri (natalizumab) can help lessen sexual dysfunction in patients with multiple sclerosis (MS), a new study shows. The study, “Patient perceived changes in sexual dysfunction ... Read more