News

June 25, 2019June 25, 2019

New Jersey Health Foundation Awards $70,000 to Kessler Foundation Researchers Studying MS and Stroke

News

Two researchers at Kessler Foundation were awarded grants of $35,000 each by the New Jersey Health Foundation to pursue their investigations into new ways to improve rehabilitative care for ... Read more

June 25, 2019June 25, 2019

FDA Approves Botox to Treat Upper Limb Spasticity in Children Aged 2 to 17

News

The U.S. Food and Drug Administration (FDA) has approved the use of Botox (onabotulinumtoxinA), marketed by Allergan, for the treatment of children ages 2 to 17 with upper limb ... Read more

June 24, 2019June 24, 2019

Health Care Needs ‘Particularly High’ in Children and Teens with MS, Study Finds

News

The burden in treating children with multiple sclerosis (MS) in terms of hospitalizations and doctor visits is extremely high, especially in the first year after diagnosis, a study from ... Read more

June 24, 2019June 24, 2019

Blocking Sortilin Protein May Be Potential Treatment for Chronic Nerve Pain, Mouse Study Suggests

News

Inhibiting the function of a protein called sortilin — an important regulator of nerve damage-induced pain in mice — may represent a potentially effective strategy for treating chronic pain ... Read more

June 21, 2019June 21, 2019

Bracco Diagnostics Notes Doctors’ Support in Developing Varibar for Assessing Dysphagia

News

As part of National Dysphagia Awareness Month this June, Bracco Diagnostics is acknowledging speech language pathologists for their support in developing Varibar (barium sulfate) products — imaging agents used to assess swallowing disorders, a ... Read more

June 21, 2019June 21, 2019

Cyxone Launches Phase 1 Trial Assessing T20K for MS

News

Cyxone launched the first-in-human Phase 1 clinical trial assessing the effects of T20K, its new therapeutic candidate for the treatment of multiple sclerosis (MS), in healthy volunteers. The announcement came ... Read more

June 20, 2019June 20, 2019

Potential Mechanism Behind Effectiveness of B-cell Depletion Therapy in MS Uncovered

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The loss of immune B-cells, and the resulting changes in the profile of immune T-cells, is a major mechanism of action for the beneficial effects seen with ublituximab treatment ... Read more

June 20, 2019June 20, 2019

Childhood MS Linked to Greater Cognitive Impairment in Adulthood, Study Finds

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People with pediatric-onset multiple sclerosis (POMS) have a greater decline in cognitive function, and are more likely to experience cognitive impairment in adulthood, than those whose disease began when ... Read more

June 19, 2019June 19, 2019

Lemtrada Lowers Levels of Nerve Damage Biomarker Better Than Rebif, Trial Data Show

News

Treatment with Sanofi Genzyme’s Lemtrada (alemtuzumab) for up to two years lowers the levels of serum neurofilament light chain (sNfL), a proposed biomarker of nerve damage, in relapsing-remitting multiple sclerosis (RRMS) patients ... Read more

June 19, 2019June 19, 2019

Duet, an Innovative Device and App, Wins Lyfebulb-Celgene 2019 MS Innovation Challenge

News

Kinza Kasher from LeoPlus USA was selected from a list of 10 finalists to receive the $25,000 grant for “Addressing Unmet Needs in MS: An Innovation Challenge,” Lyfebulb and ... Read more

June 18, 2019June 18, 2019

Immune System Activation Induced by Filgrastim Likely Beneficial for Patients with Tysabri-associated PML, Study Says

News

Immune system activation induced by filgrastim may be beneficial for patients with progressive multifocal leukoencephalopathy associated with the use of Tysabri (natalizumab), without worsening multiple sclerosis (MS) progression, a ... Read more

June 18, 2019June 18, 2019

Neurological Disease’s Progression Slows with Lowering of Iron Load in Brain, Study Finds

News

Deferiprone, a compound that lowers iron levels in the bloodstream by binding to iron molecules, can slow progression of a severe neurodegenerative disorder called pantothenate kinase-associated neurodegeneration (PKAN), a study ... Read more

June 17, 2019June 18, 2019

Relative Cancer Risk is Higher in MS Patients Who Switch Disease-modifying Treatments More Frequently, Study Finds

News

The relative risk of developing cancer was found to be higher in multiple sclerosis patients who more frequently switched between disease-modifying treatments, according to a study. In addition, researchers found ... Read more

June 17, 2019June 17, 2019

Human Blood-brain Barrier in a Chip, Created in the Lab, May Help Design New Therapies, Study Shows

News

By tweaking stem cells in a laboratory, researchers were able to generate a model of the human blood-brain barrier (BBB) in a chip. The BBB is a highly selective ... Read more

June 14, 2019June 17, 2019

New AI Method Detects Brain Changes in Response to Treatment in RRMS Patients

News

A new artificial intelligence (AI)-based model is better than conventional methods for detecting brain changes in response to treatment with Tysabri (natalizumab) in patients with relapsing-remitting multiple sclerosis (RRMS), ... Read more

June 14, 2019June 14, 2019

‘Pregnancy Compensation Hypothesis’ May Explain Greater MS Risk for Women

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A mismatch — between the ancestral immune function changes induced by the placenta and fewer modern-day pregnancies — may help explain the greater risk for multiple sclerosis (MS) and ... Read more

June 13, 2019June 13, 2019

Elevated Blood Pressure May Predict Brain Bleeding in RRMS Patients Treated with Lemtrada, Study Suggests

News

New research suggests that rising blood pressure might be predictive of intracranial hemorrhage — bleeding in the brain, a serious and sometimes fatal condition — in people with multiple ... Read more

June 13, 2019June 13, 2019

DELIVER-MS Trial Recruiting RRMS Patients to Help Improve Treatment Decision-making

News

A clinical trial based at the Cleveland Clinic and the University of Nottingham, U.K., is recruiting patients with relapsing-remitting multiple sclerosis (RRMS) to compare two treatment strategies, the National ... Read more

June 12, 2019June 12, 2019

Biotech Startup Receives Funding to Pursue Cell-based Therapies for Neurological Disorders

News

Startup company Oscine Therapeutics has received an investment from Sana Biotechnology to support the research and development of cell-based therapies for a variety of neurological disorders, including multiple sclerosis ... Read more

June 12, 2019June 14, 2019

Muralist Lydia Emily Uses Art to Publicize Hardships of Life with MS

News

Perched atop a lift at the intersection of Main and Third streets in downtown Los Angeles, artist Lydia Emily cheerfully answered questions from a reporter 2,500 miles away via cellphone ... Read more

June 11, 2019June 12, 2019

Aubagio Targets Highly Metabolic Auto-reactive T-Cells, Study Shows

News

Aubagio (teriflunomide), an approved medicine for relapsing forms of multiple sclerosis (MS), specifically targets highly metabolic and more autoreactive T-cells, analysis of the Phase 3 TERI-DYNAMIC clinical trial data shows. The ... Read more

June 11, 2019June 11, 2019

Study Identifies Possible Genetic Causes of MS

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Scientists are zeroing in on mutations in a few genes that appear to be major risk factors for developing multiple sclerosis (MS). The results of their research suggest there ... Read more

June 10, 2019

Stem Cell Therapy Based on Exosomes May Treat MS, Study in Mice Suggests

News

Exosomes — tiny vesicles secreted by cells — collected from bone marrow stem cells and injected into a mouse model of multiple sclerosis (MS) helped to treat the disease, ... Read more

June 7, 2019June 10, 2019

FDA and EMA to Review Ozanimod as Possible Oral Therapy for Relapsing MS

News

The U.S. Food and Drug Administration (FDA) and the European Medicines Agency (EMA) both agreed to review for possible approval ozanimod, Celgene‘s investigational oral therapy for relapsing forms of multiple ... Read more

June 7, 2019June 7, 2019

Obesity, Altered Fat Levels May Worsen Severity of RRMS, Study Found

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Obesity, altered lipid (fat) levels, and elevated leptin — an hormone produced by fat cells — may contribute to neuroinflammation, and worse disease severity in people with relapsing-remitting multiple ... Read more

June 6, 2019June 6, 2019

Vitamin D’s Role in MS Likely More Result of Environment Than Genes, Study Suggests

News

A study found no genetic risk factors associated with vitamin D in families with a history of multiple sclerosis (MS), suggesting that the link between vitamin D deficiency and MS ... Read more

June 6, 2019June 6, 2019

Roche, Sutter Health Testing Floodlight Mobile App That Monitors Patients’ MS

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Sutter Health, a California-based healthcare group, has partnered with the biotechnology company Roche to test a new mobile app that aims to improve monitoring of symptoms in people who ... Read more

June 5, 2019June 5, 2019

Blocking a Chemical Modification May Help Halt Inflammation in MS, Mouse Study Suggests

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The pro-inflammatory protein interleukin-17 (IL-17) drives inflammation by promoting a chemical modification, called phosphorylation, in the RNA molecule of the regnase-1 enzyme, a mouse study shows. These findings support ... Read more

June 5, 2019June 5, 2019

12-part Video Series, ‘Understanding Multiple Sclerosis,’ Available Online

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In partnership with @Point of Care, the Multiple Sclerosis Association of America (MSAA) is offering a comprehensive educational video series about multiple sclerosis (MS). The concise, 12-part series — ... Read more

June 4, 2019June 11, 2019

Vumerity’s Safety, Effectiveness Bolstered by New Data from EVOLVE-MS-1 Trial

News

Vumerity (diroximel fumarate), taken as a 462 milligram (mg) tablet twice daily, significantly decreases disease activity in patients with relapsing-remitting multiple sclerosis (RRMS), and leads to low rates of gastrointestinal side ... Read more

June 4, 2019June 4, 2019

AxoSim Licenses Mini-Brain Technology, Which May Speed Therapy Discovery for Neurological Diseases

News

AxoSim has acquired exclusive rights to lab-grown brain miniatures, coined “Mini-Brain,” a technology developed at Johns Hopkins University that uses stem cells to create models of the human brain in ... Read more

June 3, 2019June 3, 2019

Mavenclad May Surpass Gilenya as DMT of Choice for Treatment of MS in Canada

News

Mavenclad (cladribine) may surpass Gilenya (fingolimod) in the category of oral disease-modifying therapy (DMT) of choice for the treatment of multiple sclerosis (MS) in Canada, according to a press ... Read more

June 3, 2019June 3, 2019

EMD Serono and ‘MS Inside Out’ Campaign Join Global Effort to Make MS More ‘Visible’

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EMD Serono is supporting World MS Day, an initiative created by the Multiple Sclerosis International Federation (MSIF) to promote solidarity and raise awareness about multiple sclerosis (MS) worldwide, by joining efforts ... Read more

May 31, 2019May 31, 2019

Abnormal Activation of Neutrophils a Potential Therapeutic Target in MS, Mouse Study Suggests

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Targeting the excessive activation of immune cells called neutrophils, and the associated oxidative stress, may be a therapeutic strategy in patients with multiple sclerosis (MS), according to a mouse ... Read more

May 31, 2019May 31, 2019

Cyxone Nears First-in-human Trial for Investigational Preventive MS Treatment T20K

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Cyxone submitted an application to the Netherlands research ethics committee to start the first clinical trial in humans testing T20K, its investigational preventive treatment for multiple sclerosis (MS). Approval by ... Read more

May 30, 2019May 30, 2019

MS International Federation Urges Participation in Visibility Campaign on World MS Day

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The Multiple Sclerosis International Federation (MSIF) is encouraging family members, caregivers, and patients affected by multiple sclerosis (MS) to participate in World MS Day today. Created by MSIF and its ... Read more

May 30, 2019May 30, 2019

Canadians Wrap Up MS Awareness Month with ‘Acts of Greatness’ Campaign

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The Multiple Sclerosis (MS) Society of Canada closed its celebration of multiple sclerosis (MS) Awareness Month by launching the Acts of Greatness campaign that aims to raise $75 million ... Read more

May 29, 2019May 29, 2019

Celgene and MS Association of America Collaborating to Boost Knowledge on Brain Health in MS

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Biopharmaceutical company Celgene has teamed up with the Multiple Sclerosis Association of America (MSAA) to launch a new initiative called MS MindShift: A New View of MS, aimed at ... Read more

May 29, 2019May 29, 2019

Corrona Expands MS Patient Registry to Include Genentech

News

Corrona has expanded its collaborative multiple sclerosis (MS) U.S. patient registry to include Genentech, the first pharmaceutical company to participate. Established in 2017, the Corrona MS Registry is a real-world U.S.-based ... Read more

May 28, 2019May 28, 2019

IPMSSG Issues Guidelines on Participation of MS Youngsters in Clinical Trials

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The International Pediatric Multiple Sclerosis Study Group (IPMSSG) has updated its guidelines regarding the participation of children and adolescents with multiple sclerosis (MS) in clinical trials. The new series ... Read more