1st Patient Enrolled in Study of Electrical Stimulation in Treating Brain Injury

1st Patient Enrolled in Study of Electrical Stimulation in Treating Brain Injury

A first patient has been enrolled in a single-site trial to evaluate the potential of electrical stimulation, called  Electroceutical Therapy, in reducing brain injury, Endonovo Therapeutics, the therapy’s developer, announced.

Electroceutical Therapy is a non-invasive and wearable electronic device that uses pulsed electromagnetic fields (PEMF) to stimulate the central nervous system. The device repurposes the natural signals produced by the central nervous system to alleviate or mitigate symptoms of brain injury.

“We believe our technology, whose proven mechanism of action is the suppression of inflammation, has the potential to change the treatment of central nervous system disorders where neuroinflammation propagates injury such as ischemic stroke, Alzheimer’s disease, and multiple sclerosis,” Alan Collier, chief executive officer for Endonovo, said in a press release.

The study is taking place at the University of New Mexico, and will test the effects of PEMF on easing symptoms of brain injury and on biomarkers of inflammation in the blood and cerebrospinal fluid in patients with brain injury.

It plans to enroll 48 people with brain injuries who have or are fitted with an external ventricular drain to remove excess cerebrospinal fluid, the release states. These patients were enrolled in a previous study of the device’s safety and are now moving to test its effectiveness.

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The enrolled patient has severe traumatic brain injury.

Fluid samples will be collected at baseline and then every eight hours until the drain is removed. Biomarkers of inflammation and other measures, such as vital signs, blood flow, and tissue oxygenation, will be assessed.

“After completing two PEMF safety studies on volunteers and patients with brain injury currently submitted for publication, we have consented and studied our first severe traumatic brain injury patient for the PEMF study and collected brain fluid and serum samples for four days post-injury,” said Edwin Nemoto, PhD, from University of New Mexico Health Sciences Center, School of Medicine.

Endonovo  is focused on the treatment of central nervous system disorders, inflammatory conditions, and cardiovascular diseases. The company’s SofPulse Electroceutical System is approved for managing post-operative pain, swelling, and soft tissue injuries in both the U.S. and the EU.

Multiple sclerosis, a neurodegenerative, inflammatory disease, is characterized by the degradation of the myelin sheath surrounding nerve cells, resulting in brain and spinal cord injury.


    • Mark says:

      Nothing fake about this story or technology. If you are going to throw out a random comment, back it up with facts. If you do your research, you will see PEMF has proven results.

  1. Rejean says:

    OK Chris why do you say it’s fake. Do you have experience with this product to make your comment. Saying it’s fake is a very short comment that any one without any knowledge would make. I believe you have to back up your comments with serious backing up

  2. Rich says:

    If reflexology has been proven to initiate labor, is it unreasonable to consider whether a regimen of electro/chemical pulses could initiate healing in the brain.

  3. Robby Teer says:

    I had 2 herniated discs in my lower back previous to my MS diagnosis in 2012. While they did often hurt and bother me, they paled comparison to the EXTREME PAIN I developed in between my shoulder blades & back of my lower neck. My wife got me an “ALEVE DIRECT THERAPY” tens unit (sends electrical pulses up & through my spine), and it literally changed my life! I seriously don’t think I’d have made it 7 years into this disease chasing, running around, and caring for my 5 & 3 year old boys! I’ve also had nearly 70 infusions of Tysabri, which I will & do agree have “HELPED”. HOWEVER, it is by, for, & through my faith in Jesus Christ to which I account my good health. Sure, as all of us experience “BAD” days living with MS, so too do I, but nowhere NEAR to the extent to which I read about here in the forums, comments, & posts from others. I truly have been & am blessed. I urge you all, to give EMP(electromagnetic pulse) and/or TENS units a try for the pains & discomforts associated with MS. I can say that it has indeed helped this redneck, country boy from Alabama, and as Hank Williams Jr. said in one of his most famous songs, I REALLY DO have a shotgun, a rifle, and a 4-wheel drive! LOL! Therefore, y’all should know this ole’boys quite “SKEPTICAL” when it comes to “ALTERNATIVE” medicines, and being a man, I too have gotta be facing death itself BEFORE I finally give in and go to the doctor. That is, unless I wake up BLIND one morning like I did in September’12. That seemed to get me to the doctor rather quickly! HAHAHA!
    My point is, don’t knock it until you’ve tried it, because you may just be eating your words once you’ve tried it and it’s HELPED!

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