MedChew RX Shows Stability and Potential for Effectiveness in Early Tests, Company Reports
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AXIM Biotech announced that tests done on its cannabinoid-based chewing gum — MedChew Rx — showed both product stability and effective release of medicinal molecules, with a high percentage of its pharmaceutical ingredients available.
These test results may be of importance, as the company is planning to bring MedChew Rx into clinical trials as a treatment for pain and spasticity in multiple sclerosis (MS) patients.
A press release did not detail these tests, but the company previously reported that it was working with universities in the U.S. and Europe to evaluate its products. In addition to MedChew Rx, its pipeline products include CanChew+, a potential treatment for irritable bowel syndrome.
MedChew Rx is based on the combination of two cannabis components — delta-9-tetrahydrocannabinol (THC) and cannabidiol (CBD) — both of which are known to degrade over time. For this reason, measures of the gum’s stability, as well as the availability of its active ingredients, were conducted.
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The gum was seen to be stable throughout the test, and a dissolution study revealed that more than 90 percent of its active pharmaceutical ingredient was released and available to potentially offer benefit.
“Data from these studies is an essential component in manufacturing as well as regulatory submissions and we are pleased to see such positive results for our MedChew Rx program,” George E. Anastassov, MD, chief executive officer of AXIM Biotech, said in the release.
“While we knew our controlled-release chewing gum delivery system would deliver the molecules with increased bioavailability to the body, we needed to ensure that the molecules would remain stable and available in this format,” Anastassov added. “Not only did we see this, but we measured an industry-leading stability in THC, which is a notoriously unstable molecule.”
Plans for a first clinical trial of MedChew as a potential MS treated of pain and spasticity were approved by Dutch regulators in early 2018. Results from this stability and dissolution study will be valuable for the entire MedChew Rx pharmaceutical development program, testing MedChew to provide symptomatic relief to MS patients.
In addition, “this data will be essential to monitor quality and batch-to-batch consistency of our products after we have received regulatory approval and are selling on the market,” Anastassov said.
The company announced earlier this year that it had patented a new technology to extract high quality, pharmaceutical-grade THC to be used in its formulations.
Sherry Drinkwine-Letteney
I am interested in hearing more about this and if there are human studies being done, I'd be interested in taking part. I have secondary MS.
Elaine Kaplan
I am very interested in this product. I have RRMS and would love to be part of a trial
Mary Gerdt
I really hope this approach will be validated by Lawmakers, Insurance companies, Medicare, VA, Medicaid.
And my insurance would cover.
Sharon Dudley
I would love to try this. Hopefully it would give me some relief
Magda
I would also like to try this please.
I have fibromyalgia.
María Patricia Barbosa de Trujillo
I need More information abouth this product,shippingprice to Colombia,. Thanks
Patricia Beck
Hi I am interested in hearing more about this please. I have fibro and herniated discs. Also arthritis.
Laura De tejeria
Hi I am very interested. I have fibro and arthritis. I have pain in my body I don't can walk and work I need help.
Thanks.
Aníbal Tavares
Where we can buy this medicine?
Is there a site where we can find to buy? Store?
Brooke Darby
When will this be available to purchase? I’m interested to purchase for arthritis and fibromyalgia
Charmaine Marigliano
I have fibromyalgia, arthritis and degenerative disc disease and would like to try this gum. Were can I buy?
Paloma Pérez Sanz
I'd love to try the chewing gum, I have fibromyalgia. Can you tell me when will it be available, please? Thank you for your help.
Amarylis Vazquez
From where I can get it. I have fibromyalgia and arthritis. It's already approve to sale it in USA and it's true, where can I buy it?
Brigitte Reynaert
I am living in Spain and would immediately buy it, of possible! Where could I find it?
Eloísa
I’m interested on the product, but I’m from Perú, how can I get it?
Rosalia Moreno
Oh my God, where I can buy this medicine? I need a better life, free of pain. I have fibromyalgia and arthritis. Thank you for your help.
Emma Zuniga
I have fibromyalgia and arthritis ,I need a better life,free of pain Please.ThanKs you for your help.I can buy this medicine?
Lisette Santiago
I have fibromyalgia and would like to participate in the test study.please contact me please.
Debbie cairns
Would be interested in trying this I suffer with fibromyalgia me/cfs arthritis lupus diabetes crohn's disease lymphodema and a prolapse bulging disc impinging on nerve roots. I suffer chronic pain 24/7 an am on high level medication so far not helping I would cry out for some relief.
cbrissy
I am looking to buy med cbd gum for fibro. thanks
Amalia Arcodia
I have herniated discs and fibromyalgia. I live in Italy, is it possible to buy here or have it shipped here?
Tina
I would love to try this. I have fibromyalgia and this pain is unbearable!
Lawrence Fehrenbacher
I would really like to try this product for my neuropathy pain. I live in Ohio were medical marijuana is legal. Is there anyway to get it here to OHIO?
Susan Kirby
How do we order this gums?