Phase 1/2 trial will test cell therapy rese-cel in relapsing, progressive MS
Cabaletta Bio is getting set to launch a clinical trial testing its cell therapy resecabtagene autoleucel (rese-cel) in people…
Articles by Marisa Wexler, MS
Menopause may accelerate the progression of MS: Study
For women with multiple sclerosis (MS), disability starts to worsen significantly faster after menopause, according to a new study.
OCS-05 shows safety, aids vision with optic neuritis in Phase 2 trial
OCS-05, an experimental medication that Oculis is developing to treat acute optic neuritis, a common symptom of multiple…
IRX4204 promotes myelin repair, improves gait in MS mouse model
IRX4204, a compound that Io Therapeutics is developing to treat neurological diseases, facilitated myelin repair and improved walking…
Long-term Tecfidera slows MS disability progression in large trial
Treatment with Tecfidera (dimethyl fumarate) significantly reduces relapse rates for people with multiple sclerosis (MS), and most MS…
Health issues seen in MS children in 5 years before diagnosis: Study
In the five years leading up to a multiple sclerosis (MS) diagnosis, children and adolescents often…
MS treatments don’t raise miscarriage, birth defect risk: Study
Most treatments for multiple sclerosis (MS) don’t increase the risk of major problems when used during pregnancy, an analysis…
Top 10 MS news stories of 2024
The team at Multiple Sclerosis News Today has brought our audience the latest news about treatments, scientific research, and…
Paramagnetic rim lesions linked to MS disability progression
A specific type of brain lesion called a paramagnetic rim lesion, or PRL, is associated with worse disability over time…
Brain damage in MS children linked to lower socioeconomic status
Children with multiple sclerosis (MS) who come from poorer families or other disadvantageous circumstances tend to have more inflammation…
High cholesterol linked to MS cognitive impairment in study
Higher cholesterol levels are associated with worse cognitive impairments in people with multiple sclerosis (MS), a study reported. The…
Noninvasive brain stimulation could boost MS physical therapy benefits
Adding noninvasive brain stimulation to physical therapy may help people with multiple sclerosis (MS) improve their balance and walking…
MS medication Fampyra may help people with poor working memory
Fampyra (fampridine), an oral medication that’s approved to improve walking ability in adults with multiple sclerosis (MS), may…
Study IDs 2 enzymes that mediate toxic effects of saturated fats in MS
Two enzymes in brain cells are responsible for mediating the toxic effects of certain fat molecules in multiple sclerosis…
Keto diet modifies gut bacteria in mice, protecting against MS
A ketogenic diet — a very low-carbohydrate, high-fat eating plan called a keto diet for short — was able…
Hope Biosciences’ stem cell therapy shows promise in small Phase 2 trial
A mesenchymal stem cell therapy led to significant improvements in quality-of-life scores for people with multiple sclerosis (MS) in…
Scientists create platform for devices that wrap around nerve fibers
A new technology is designed to be a “wearable” device for neurons, wrapping around individual nerve fibers with a goal…
EC slaps Teva with €463M fine over misuse of Copaxone patents
The European Commission (EC) fined Teva Pharmaceuticals €462.6 million — more that $502 million — after an investigation…
Brain blood vessels key to new MS treatments, researchers argue
Developing a more comprehensive understanding of the interactions between the brain, blood vessels, and the immune system holds great promise…
Cholesterol medications might be able to be repurposed for MS: Study
Increased production of cholesterol by stem cells in the brain contributes to neurological damage in multiple sclerosis (MS), according…
Ancient viral genes in human DNA linked to MS in study
Abnormal activity of ancient viral genes may play a role in the development of multiple sclerosis (MS) and other…
Comorbidities raise risk of disease activity, disability progression
People with multiple sclerosis (MS) who have multiple comorbidities, or co-occurring health problems, are more likely to experience disease…
Modafinil and talk therapy are both useful for easing MS fatigue: Study
Treatment with modafinil, a medication used to reduce excessive sleepiness, and cognitive behavioral therapy (CBT) can both provide clinically meaningful…
Adult myelin-making cells display unique marker affecting activity
A specific epigenetic marker, or a chemical modification in DNA that alters gene activity, may explain why adult oligodendrocyte progenitor…
Moderate alcohol consumption tied to slower RRMS disability pace
People with relapsing-remitting multiple sclerosis (RRMS) who drink low to moderate amounts of alcohol have significantly less disability progression…
MS and gut microbiome pattern similar across US, Asia: Analysis
People with multiple sclerosis show subtle alterations in gut bacteria that seem to be consistent across populations in the…
PIPE-307 shows potential to repair myelin in MS mouse model
PIPE-307, an experimental oral therapy that’s currently in Phase 2 testing for relapsing-remitting multiple sclerosis (RRMS), was shown to…
Machine learning may help predict disability progression in MS: Study
A machine learning algorithm may be able to accurately predict whether or not people with multiple sclerosis (MS) will…
Protein connexin 43 shows potential as treatment target for MS
Blocking the activity of a protein called connexin 43 (Cx43) may be an effective strategy to treat multiple sclerosis…
Foralumab wins FDA fast track designation for nonactive SPMS
Tiziana Life Sciences has received fast track designation from the U.S. Food and Drug Administration (FDA) for its intranasal…