Gail Pickens-Barger is a doTERRA Elite Wellness Advocate who has been helping students to improve their fitness for 15 years. The yoga instructor is now also dedicated to serving the fitness goals of a particular population — patients with multiple sclerosis (MS). MS is a demyelinating disease in which the insulating layer (called myelin) that…
In a special feature published in the journal American Health & Drug Benefits, authors Stanton R. Mehr, President of SM Health Communications, and Marj P. Zimmerman, President of RxDirections, discuss the many unmet medical needs multiple sclerosis (MS) patients still face in dealing with the…
A new study investigated the influence of sleep disturbance, fatigue and disability on the quality of life (QOL) in multiple sclerosis (MS) patients. Health-related QOL measurements are important tools for assessing the impact of a disease on self-reported physical, mental, emotional, and social functioning. Most studies show that QOL is not related to…
Novoron Bioscience, Inc., a biotech company focused on developing therapies for disorders of the central nervous system, recently announced that it has received a $680,000 National Institutes of Health (NIH) grant to assess the potential of a new therapeutic approach to induce remyelination in multiple sclerosis (MS). MS is…
A new Canadian study, published in the International Journal of MS Care, has concluded that the majority of patients with concurrent multiple sclerosis (MS) and depression are receiving antidepressant treatment. Despite this, however, many of these patients continue to report depressive symptoms. MS and depression co-occurrence is…
Difficulties with cognitive function and fatigue are the main reasons patients with multiple sclerosis (MS) struggle to stay gainfully employed, a new study published in the December edition of the International Journal of MS Care has found. The study is titled “Factors Associated with Employment Status in Individuals with…
People caring for multiple sclerosis (MS) patients can have substantial physical and psychological health concerns, and their care can adversely impact their employment, according to research findings recently published in the International Journal of MS Care. The study is titled “Care Partners and Multiple Sclerosis,…
Multiple Sclerosis News Today has reported the latest therapies, clinical trial developments, and events in multiple sclerosis (MS) on a daily basis throughout the past year. As 2015 comes to an end, here are the year’s 10 articles most widely read by Multiple Sclerosis News Today readers, each with a brief summary of the developments…
GeNeuro, a company developing therapies for neurological and autoimmune disorders, recently announced the initiation of a Phase 2b clinical trial to assess its lead investigational antibody GNbAC1 in patients with relapsing-remitting multiple sclerosis (RRMS). The trial, called “CHANGE-MS,” plans to enroll 260 patients across 68 centers across the European Union and…
A team of researchers from the Netherlands have developed an interactive web-based program called MSmonitor that offers multiple sclerosis patients a way to manage and better integrate the multidisciplinary care they require. Pilot data from a study of its use is detailed in the article, “The interactive web-based program MSmonitor for…
Alkermes plc, a biopharmaceutical company focused on therapies for the treatment of central nervous system (CNS) disorders, announced that it has successfully met its 2015 goals for their product and late-stage pipeline drug portfolio, including ALKS 8700, a monomethyl fumarate (MMF) drug candidate for the treatment of multiple sclerosis…
Akaal Pharma, a developer of small molecule drugs for the treatment of inflammation and autoimmune diseases including multiple sclerosis (MS), recently announced highly positive preclinical trial results on the safety and efficacy of its drug candidate AKP-11 when compared to Gilenya (fingolimod, FTY-720), an oral MS drug approved by…
The National Multiple Sclerosis Society announced that a panel of experts led a comprehensive review of 142 published studies addressing rehabilitation in multiple sclerosis (MS), and found evidence suggesting that weekly in-home or outpatient physical therapy offers benefits — but, mostly, it found a lack of well-designed studies into…
Researchers in the United Kingdom recently discovered that a small molecule triggers the destruction of axons, a phenomenon observed in neurodegenerative diseases like multiple sclerosis (MS). The study is titled “Wallerian Degeneration Is Executed by an NMN-SARM1-Dependent Late Ca2+ Influx but Only Modestly Influenced by Mitochondria” and appears in the journal…
The Multiple Sclerosis Society of New Zealand (MSNZ) announced that PHARMAC has agreed with its request to finance two novel first-in-line therapies for relapsing-remitting forms of multiple sclerosis (MS), making them accessible to patients there. PHARMAC recently agreed to fund the two treatments, teriflunomide (Aubagio), supplied by Sanofi-Aventis NZ, and dimethyl fumarate (Tecfidera),…
Dr. Jerry S. Wolinsky of the University of Texas in Houston, will give the first Kenneth P. Johnson Memorial Lecture at the opening day of the Americas Committee for the Treatment and Research in Multiple Sclerosis (ACTRIMS) Forum 2016 in New Orleans, focusing on distinctions between relapsing and progressive disease forms. ACTRIMS…
Dr. Bradley Bowser, a South Dakota State University (SDSU) researcher and assistant professor, is investigating whether the practice of exercise, either by itself or together with cognitive behavioral therapy, can effectively improve mobility and quality of life in patients with multiple sclerosis (MS). MS is a neurodegenerative condition that often induces…
A new study in the Journal of Cell Biology suggests that vitamin D activates a receptor involved in myelin regeneration in patients with multiple sclerosis (MS). The study, entitled “Vitamin D receptor–retinoid X receptor heterodimer signaling regulates oligodendrocyte progenitor cell differentiation,” and was led by researchers…
A research team from the University of Alberta, Canada, is exploring a new therapeutic way of reducing brain inflammation in multiple sclerosis (MS) patients with fewer side effects. The study, titled “Granzyme B-inhibitor serpina3n induces neuroprotection in vitro and in vivo,” appeared in the Journal of Neuroinflammation. Most available…
Juntendo University Hospital, the first medical school in Japan to adopt Western medicine, recently signed a research agreement with SyntheticMR to employ the company’s SyMRI technology in clinical research projects at the hospital involving patients with multiple sclerosis (MS) or brain tumor metastases. SyntheticMR is a Swedish company developing and commercializing software…
The holidays can be stressful on everyone, and especially on those with multiple sclerosis (MS). A health specialist is offering these eight suggestions to MS patients and their families as a way to enjoy this season, and to keep it as free as possible of disease flares or symptom worsening. Increased demands on daily routines, travel,…
Takeda Pharmaceutical, a pharmaceutical company based in Osaka, Japan, recently announced that a widely approved drug treatment for the prevention of relapses in multiple sclerosis (MS) is now available in Japan as well. Copaxone, (glatiramer acetate; 20 mg daily subcutaneous injection), developed by Teva Pharmaceuticals, is an immunomodulatory drug designed to act as…
Brickell Biotech, Inc., a pharmaceutical company developing novel therapies in the field of dermatology, recently announced it has exclusive worldwide rights over a series of new, retinoic acid-related orphan nuclear receptor gamma (RORy) inhibitors from the New York University (NYU) and Orca Pharmaceuticals. As part of the agreement, Brickell will be…
RedHill Biopharma, Ltd., recently announced the conclusion of the last dosing and patient follow-up visit for its Phase 2a proof-of-concept study to assess the efficacy and safety of the experimental drug RHB-104 as an add-on therapy to interferon beta-1a in patients with relapsing-remitting multiple sclerosis (RRMS).
The Multiple Sclerosis Society of Canada and the Multiple Sclerosis Scientific Research Foundation recently announced the funding of new research on pediatric multiple sclerosis (MS) and on the role played by the gut microbiome in brain and autoimmune diseases. Although only around 5% of all newly diagnosed MS cases…
Synthetic Biologics, which specializes in the development of therapies for pathogen-specific diseases, recently announced the publication of new and positive data on results from a Phase 2 clinical trial evaluating the company’s product Trimesta™ as a treatment for relapsing-remitting multiple sclerosis (RRMS) in women. Professor Rhonda Voskuhl, director of the Multiple Sclerosis Program…
The National Multiple Sclerosis Society awarded a $700,000 research grant to Dr. Bonnie Dittel, a senior investigator at the BloodCenter of Wisconsin (BCW) and adjunct professor at the Medical College of Wisconsin. The grant will help Dr. Dittel advance her research into how specific immune cells in the body can…
The National Multiple Sclerosis Society recently announced that a research team is recruiting 132 patients with a diagnosis of neuromyelitis optica spectrum disorders (NMOSD) for a Phase 3 clinical study comparing an experimental medicine with an inactive placebo. NMOSD is a rare disorder caused by immune system cells attacking…
Ms. Margaret Cadden, a Pennsylvania State University doctoral student in Clinical Psychology, has been selected by the American Psychological Foundation (APF) as the recipient of the 2015 APF Scott and Paul Pearsall Scholarship prize of $10,000. The scholarship will be used to research depression, stigma, and disease progression in individuals with varying…
Opexa Therapeutics announced that it has been named one of the “Top Projects to Watch” for the third consecutive year. A panel of independent experts recognized the biopharmaceutical company for its work in the development of personalized immunotherapies for autoimmune disorders, such as multiple sclerosis (MS) and neuromyelitis optica (NMO). Opexa was…
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