April 15, 2021 News by Steve Bryson, PhD Ocrevus Use Linked to PML in Man, 78, With PPMS, Case Report Says A 78-year-old man withĀ multiple sclerosis (MS) developed the brain infection progressive multifocal leukoencephalopathy (PML) after two years of treatment with Ocrevus (ocrelizumab), a recent case report detailed. Treatment was discontinued and, as the patient’s symptoms worsened, he was moved to off-label…
May 25, 2017 News by Patricia Silva, PhD PML Found in Ocrevus-Treated Patient Who Had Used Tysabri for 3 Previous Years A multiple sclerosis (MS) patient treated in Germany withĀ Ocrevus (ocrelizumab)Ā has developed the dreaded brain infection progressive multifocal leukoencephalopathy (PML).Ā But it is not clear whether the recently approvedĀ Genentech/Roche-developed treatmentĀ is the cause. The patient took the last dose of a three-year course of Tysabri (natalizumab)Ā in February. Tysabri is…