AXIM Biotech has closed on a private funding round that will enable it to continue clinical trials for a variety of conditions, including its pharmaceutical candidate MedChew Rx, a patented cannabinoid release chewing gum for treating pain and spasticity in multiple sclerosis (MS).
According to a press release from SECFilings.com, a major business focus of AXIM is on the research, development and production of pharmaceutical, nutraceutical, and cosmetic products based on cannabinoids, particularly the development of novel and more effective therapeutic delivery methods for these and other compounds.
AXIM’s CanChew is the first patented controlled-release cannabinoid chewing gum, and is currently available as an over-the-counter supplement. CanChew chewing gum has a unique oral mucosal absorbance delivery system. Its active ingredient is the hemp-derived cannabinoid compound cannabidiol (CBD), which does not produce a “high” effect.
According to the CanChew website, the product is nonhabit forming, does not require a prescription, is available in all 50 states, is mint-flavored, and has no artificial sweeteners or preservatives.
The company says its pharmaceutical candidate MedChew Rx is the first patented cannabinoid release chewing gum for treating pain and spasticity in MS. MedChewRx combines the cannabinoids cannabidiol (CBD, 5 mg) and tetrahydrocannabinol (THC, 5 mg), both naturally extracted and synthetic, as its active ingredients. AXIM anticipates a release date as early as 2017.
Medical cannabis holds promise as a potential therapy for some specific, difficult-to-treat pain associated with disorders like MS and other conditions that cause nerve pain. AXIM hopes MedChew RX will be soon be approved for therapeutic use for MS by the U.S. Food and Drug Administration (FDA) and the European Medicines Agency (EMA).
In addition to treating nerve pain, AXIM’s researchers have proven that the act of chewing — known as mastication in the medical community — could also have benefits in treating neurological disorders. A growing body of research supports the theory that chewing could have therapeutic value in helping to prevent cognitive dysfunction by changing internal carotid arterial blood flow and thereby increasing cerebral circulation.
As a result, the act of chewing gum could stimulate regional increases in neuronal activity that could reap cognitive benefits. Mastication combined with the therapeutic action of MedChew Rx’s cannabinoid APIs (active pharmaceutical ingredients) is believed to offer greater effectiveness than that of existing medications. AXIM’s online Research Library provides links to selected research papers and articles on research into mastication as therapy and related topics.
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