Patients with multiple sclerosis (MS) report moderate scores in mental and physical health, as measured by three, well-established quality-of-life scales, according to an analysis of published literature.
The study, “Global, regional and national quality of life in patients with multiple sclerosis: a global systematic review and meta-analysis,” was published in the journal BMJ Supportive & Palliative Care.
As the symptoms of MS can vary in severity from patient to patient, researchers at the Iran University of Medical Sciences sought to analyze the health-related quality of life of MS patients globally.
To do so, the researchers conducted a systematic review and meta-analysis of articles referencing health-related quality of life in MS patients, published from January 2000 to April 2020.
In total, 54 published articles were selected. All studies measured quality of life with one of three scales — the 36-item Short Form Survey (SF-36), the MS Quality of Life-54 (MSQoL-54), or the MS International Quality of Life questionnaire (MusiQoL).
The SF-36 is a 36-question survey issued to the general public to evaluate health-related quality of life. Based on the answers, participants receive a score from zero to 100, with zero indicating the worst possible health status and 100 indicating the best health.
The MSQoL-54 is a modified version of the SF-36, featuring the original 36 general questions and an additional 18 questions that are specific to the symptoms of MS. The resulting scores also range from zero to 100.
Finally, the MusiQoL survey is specifically designed to evaluate quality of life in MS patients, with 31 items that focus on the multiple dimensions of the disease and scores also ranging from zero to 100.
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