Biogen Idec, one of the first true biotech companies specializing in products indicated for neurodegenerative diseases, hematologic conditions, and autoimmune disorders, is preparing to present over 90 poster presentations during this week’s 6th Joint ACTRIMS-ECTRIMS Meeting. The event is scheduled to take place from Wednesday, September 10th through Saturday the…
treatment
Those attending this week’s ACTRIMS-ECTRIMS convention set to take place on the 10th of September until the 13th in Boston, can expect Swiss pharmaceutical company Novartis to present promising findings on Gilenya (fingolimod) — the company’s leading oral formulation for relapsing-remitting multiple sclerosis (RRMS). In previously completed studies and clinical trials,…
A new study, entitled, “Intestinal barrier dysfunction develops at the onset of experimental autoimmune encephalomyelitis, and can be induced by adoptive transfer of auto-reactive T cells” conducted at University of Lund, Sweden, published on PlosOne by the research group of Dr. Shahram Lavasani in collaboration with…
A novel therapeutic from GeNeuro to treat multiple sclerosis showed promising results in a one-year, open-label extension phase 2a clinical trial. GeNeuro tested its first-in-class GNbAC1 monoclonal antibody in ten multiple sclerosis patients, nine of whom have primary or secondary progressive multiple sclerosis. “We are very excited by the…
Researchers from the University of Bristol have found a way of convert the function of cells into protecting the body instead of destroying healthy tissue, in what could be an important breakthrough for the treatment of debilitating autoimmune diseases in which the immune system mistakenly attacks the body, like…
Novartis has announced that it will present new analyses and redefined treatment goals for multiple sclerosis (MS) at the 2014 Joint Americas and European Committees for Treatment and Research in Multiple Sclerosis Meeting (ACTRIMS-ECTRIMS), which is taking place in Boston, between September 10 and 13. Novartis claims to have…
In-vitro laboratory experiments using stem cells have long-since been the subject of debate between scientists and naturalists, but when it comes to developing effective methods to grow human cells and tissue for use in a potentially life-saving procedure or restoration of bodily function, researchers are increasingly more confident that…
The U.S. Food and Drug Administration (FDA) accepted the abbreviated new drug application (ANDA) for filing of a Glatiramer Acetate Injection for the treatment of patients with relapsing forms of multiple sclerosis (MS).
As researchers continue to develop a clearer understanding of the underlying causes of multiple sclerosis (MS), it is becoming increasingly apparent that the future of treating the disease is likely to center on neural protection and a reversal of the demyelination process that strips away the critical insulation…
Low dose naltrexone (LDN) may be on its way to becoming a new therapeutic agent for multiple sclerosis. Evidence for its efficacy in attenuating multiple sclerosis symptoms is scarce, but results of a phase 3 clinical trial, “A Randomized Placebo-Controlled, Crossover-Design Study of the Effects…
The Pharmaceutical Management Agency (PHARMAC) is considering a funding proposal that includes five treatments for multiple sclerosis (MS), namely two key MS drugs, Biogen‘s Tysabri and Novartis‘ Gilenya, that are not currently funded. PHARMAC is the New Zealand Crown agency that decides, on behalf of District…
Fingolimod is a disease modifying therapy (DMT) used to treat relapsing remitting multiple sclerosis (RRMS) patients as well as patients who continue to present with relapses despite treatment with beta interferon drugs, and is the first oral medication to be approved by the U.S. Food and Drug…
Biogen Idec, a biotechnology company focused on developing innovative therapies for the treatment of neurodegenerative diseases, hematologic conditions and autoimmune disorders, has announced that the U.S. Food and Drug Administration (FDA) has approved PLEGRIDYTM (peginterferon beta-1a), a new treatment for people with relapsing forms of multiple sclerosis…
Welsh health minister Mark Drakeford has announced that Wales has become the first UK country to authorize a cannabis-based medicine under its National Health Service. Sativex, a proprietary oral spray cannabinoid medicine that has been licensed in the UK to treat muscle spasms and stiffness in people…
Regulus Therapeutics, Inc., a San Diego-based biopharmaceutical company that specializes in the research and development of experimental drugs that target microRNAs, recently announced that it has signed a contract to work together with Biogen Idec. Under Regulus’ microMarkers™ project, the two companies will be collaborating on research efforts to…
A new stem cell transplant therapy may offer patients with multiple sclerosis (MS) an alternative treatment option. According to a recent report on KCBD by Kasie Davis, researchers are pointing to the success of an MS patient named Dan Tiel, who had been reduced to living in a wheelchair due to…
According to a study published in the Journal of Neurology Neurosurgery & Psychiatry, HIV infection is correlated to a significantly lower risk of developing multiple sclerosis (MS). The researchers analyzed a previous report by a team of Danish researchers whereby an HIV positive man with MS had his symptoms…
Findings of a number of scientific research articles, reviewed in a recent article from researchers at University of Bari and National Cancer Institute in Italy, describe a common response to injury in multiple sclerosis patients and animal models of experimental allergic encephalomyelitis (EAE). The response, known as…
UPDATE: Australian Authorities Warn About Unapproved MS Stem Cell Treatments After Death in Russia
Australian authorities are alerting Multiple Sclerosis patients to the risk of unproven stem cell treatments that are being performed both in the country and overseas, after the recent death of a woman in Russia undergoing a controversial treatment for the disease. The continued marketing campaigns to…
Scientists at The New York Stem Cell Foundation (NYSCF) Research Institute have made encouraging advances in the development of a viable cell replacement therapy for multiple sclerosis using a patient’s own cells, known as induced pluripotent stem cells (iPSCs). Since multiple sclerosis is a chronic demyelinating disease of unknown…
In spite of an eight week delay, New Zealand-based Innate Immunotherapeutics is still planning to enroll patients for its phase 2b clinical trial that will study the experimental drug MIS416 for secondary progressive MS. The clinical research organization (CRO) involved in the management of the trial informed the company about the…
The European Commission granted marketing authorization for the use of Plegridy, a drug developed by Biogen Idec as a treatment for adults with relapsing-remitting multiple sclerosis (RRMS), the most common form of multiple sclerosis (MS). The approval comes at a time when…
Complementary and alternative medicine (CAM) are no substitutes for the regular treatment of multiple sclerosis (MS), however, they are becoming more common among patients as a way of alleviating the symptoms of the disease. Massage therapy is an example of that. 36-year-old Jessica Rich is a patient who embraced…
The U.S. Food and Drug Administration (FDA) recently notified Concert Pharmaceuticals that the company had fulfilled all necessary preclinical toxicological tests for the oral therapy CTP-354 for the treatment of multiple sclerosis, spinal cord injury, and spasticity. The authorization to administer repeated doses of the compound, in excess of 6 mg per day,…
A Ph.D. student at the University of Southern California (USC) Viterbi Ming Hsieh Department of Electrical Engineering, Kun Yue, is developing a model of selected brain circuits to study multiple sclerosis (MS) in an effort to develop a nanotechnology based treatment for the disease. Yue believes that new technology can lead…
The UK’s National Institute for Health and Care Excellence (NICE) gave a positive final appraisal determination to the use of the Biogen Idec‘s drug Tecfidera (dimethyl fumarate) in adults for the treatment of relapsing-remitting multiple sclerosis (RRMS), having turned back on their preliminary negative recommendation. The oral…
Alkermes plc is looking to add one more treatment to the repertoire for multiple sclerosis drugs by initiating a Phase 1 clinical trial study of ALKS 8700. This novel molecule, developed by Alkermes, will be evaluated for safety, tolerability, and pharmacokinetics. “We expect the results of this study to…
Eight new drugs that are able to stimulate the nervous system were discovered by a research team at UC San Francisco recently. The team utilized a novel screening platform and examined the cellular effects of 1,000 chemical compounds. The scientists believe the discovery may impact the treatment of the tissue…
Startup biotech company ImStem Biotechnology is looking to raise additional funding for their upcoming clinical trials after publishing promising research on a unique stem-cell treatment used on mice with multiple sclerosis. The company has already received previous funding…
The Scottish Medicines Consortium (SMC) announced the approval of the drug Lemtrada, produced by Genzyme, for the treatment of adult patients with relapsing-remitting multiple sclerosis (RRMS) and active disease defined by clinical or imaging features, within the national health system (NHS) in Scotland. Lemtrada…