Helius opposes Medicare, Medicaid coverage amounts for PoNS device
Helius Medical Technologies is opposing new decisions from the U.S. Centers for Medicare & Medicaid Services (CMS) that stipulate…
Articles by Lindsey Shapiro, PhD
Genetic modifications to myelin-making cells boost myelin repair
Transplanting genetically engineered oligodendrocyte progenitor cells (OPCs), which give rise to mature myelin-making cells, significantly boosted myelin repair in…
Phase 2 trial of oditrasertib in MS patients stopped after goals not met
Sanofi has ended a Phase 2 clinical trial into oditrasertib, an investigational RIPK1 inhibitor therapy, in people with relapsing…
Tecfidera with immune tolerizing cell therapy shows promise for MS
Combining the approved medication Tecfidera (dimethyl fumarate) with targeted therapy using a patient’s own immune cells may eventually be…
New twin study implicates certain T-cells in early MS inflammation
By studying pairs of identical twins, researchers have identified a population of immune cells whose early activation and migration into…
Acupuncture may have benefits for reducing MS fatigue, per small study
Acupuncture may be a promising complementary approach for easing fatigue and improving quality of life for people with multiple…
ECTRIMS 2024: Tolebrutinib may target smoldering inflammation
Sanofi’s tolebrutinib significantly delayed disability progression, by 31%, and increased the rates of disability improvement compared with a placebo…
ECTRIMS 2024: MS relapse rates fall with 5 years on Briumvi
Continuous treatment with Briumvi (ublituximab) over five years was associated with low rates of relapses and confirmed disability progression…
New collaboration will evaluate segesterone acetate as MS therapy
The pharmaceutical company Médunik Canada and Population Council, a nonprofit research organization, are teaming up to investigate the…
Trial tests cognitive rehab with VR-based exercise to boost memory
A clinical trial is evaluating whether combining a cognitive rehabilitation program with a virtual reality (VR)-based aerobic exercise regimen will…
1-year fenebrutinib curbs nearly all disease activity in relapsing MS trial
A year of treatment with the experimental BTK inhibitor fenebrutinib was safe and nearly entirely suppressed signs of disease…
Researchers identify mechanisms of dysfunctional Tregs in MS
Researchers uncovered a mechanism by which regulatory T-cells (Tregs), immune cells that keep the immune system in check and prevent…
Study may explain link between obesity, higher MS risk in women
Obesity promotes molecular signatures associated with more inflammation and multiple sclerosis (MS) signaling pathways specifically in females, which may…
Cognitive impairments affect about a third of RRMS patients: Analysis
About a third of people with relapsing-remitting multiple sclerosis (RRMS) exhibit cognitive impairments, according to a review by Australian…
MS patients show greater resistance to insulin effects, analysis finds
Multiple sclerosis (MS) patients exhibited greater resistance to the effects of insulin — the hormone responsible for keeping the…
Backward walking speed may be screening tool for mobility in MS
Measures associated with how well individuals can modulate their backward walking speed could be used as a screening tool for…
Immune cell behavior could inform MS treatment strategies: Study
Researchers have identified characteristics of regulatory T-cells (Tregs) — a family of immune cells that help keep harmful immune reactions…
Cognitive rehab tied to MRI changes in cognition-linked brain regions
A three month cognitive rehabilitation program, with or without aerobic exercise, increased tissue volume and activity in brain regions linked…
Updated guidance eases Mavenclad MRI requirements in England
England’s National Institute for Health and Care Excellence (NICE) has updated its guidance on the use of Mavenclad (cladribine)…
Large US trial to test online programs for treating MS fatigue
A large clinical trial to test online programs for treating fatigue in people with multiple sclerosis (MS) will…
Resistance training exercises may benefit middle-aged MS patients
Resistance training by middle-aged people with multiple sclerosis (MS) was linked with significant improvements in muscle strength in a…
MS Australia report highlights need for faster diagnosis of MS
MS Australia released a report highlighting the critical need for faster multiple sclerosis (MS) diagnoses. While diagnostic delays…
Virtual reality therapy for cognition, mood needs more study: Review
Rehabilitation approaches involving virtual reality (VR) may have beneficial effects on cognitive function and anxiety in people with multiple…
CSF biomarkers at time of diagnosis may aid in MS prognosis: Study
Certain biomarkers in the cerebrospinal fluid (CSF) — the fluid surrounding the brain and spinal cord — around the time…
Specialized PET scan shows chronic inflammation tied to MS progression
A specialized imaging approach was able to detect signs of persistent inflammation in the brains of people with multiple…
Autoantibodies seen in blood years before MS diagnosis: Study
Researchers have identified a distinct profile of self-reactive antibodies that appear in the blood years before the first clinical signs…
AAN 2024: Earlier Ocrevus lowers MS progression risk over 10 years
Ocrevus (ocrelizumab) continued to prevent disability progression among people with relapsing and progressive forms of multiple sclerosis (MS)…
AAN 2024: Long-term data support early Kesimpta start in relapsing MS
For people recently diagnosed with multiple sclerosis (MS), first-line treatment with Kesimpta (ofatumumab) was associated with a lower…
AAN 2024: Ocrevus benefits Black, Hispanic patients same as whites
Ocrevus (ocrelizumab) had similar benefits in Black and Hispanic multiple sclerosis (MS) patients as earlier clinical trials with…
Improved fatty acid profiles tied to cognitive gains with two MS diets
The Swank and Wahls diets, which are used by people with multiple sclerosis (MS), were associated with improvements in…