An interplay between genetic and environmental risk factors, including tobacco smoke exposure, affects brain development in early childhood, which could…
Articles by Lindsey Shapiro, PhD
Blood levels of neurofilament light chain (NfL) — a biomarker of nerve cell damage used in multiple sclerosis (MS)…
Roche signed a definitive agreement to acquire Poseida Therapeutics, a deal that includes Poseida’s portfolio of CAR T-cell therapy candidates…
Activation of a protein called DLK may drive the death of nerve cells that have been demyelinated, or lost their…
The number of people living with multiple sclerosis (MS) in Australia rose by more than 50% in the decade…
An independent data monitoring committee has recommended that the twin ENSURE Phase 3 trials testing vidofludimus calcium in people…
Helius Medical Technologies is opposing new decisions from the U.S. Centers for Medicare & Medicaid Services (CMS) that stipulate…
Transplanting genetically engineered oligodendrocyte progenitor cells (OPCs), which give rise to mature myelin-making cells, significantly boosted myelin repair in…
Sanofi has ended a Phase 2 clinical trial into oditrasertib, an investigational RIPK1 inhibitor therapy, in people with relapsing…
Combining the approved medication Tecfidera (dimethyl fumarate) with targeted therapy using a patient’s own immune cells may eventually be…
By studying pairs of identical twins, researchers have identified a population of immune cells whose early activation and migration into…
Acupuncture may be a promising complementary approach for easing fatigue and improving quality of life for people with multiple…
Sanofi’s tolebrutinib significantly delayed disability progression, by 31%, and increased the rates of disability improvement compared with a placebo…
Continuous treatment with Briumvi (ublituximab) over five years was associated with low rates of relapses and confirmed disability progression…
The pharmaceutical company Médunik Canada and Population Council, a nonprofit research organization, are teaming up to investigate the…
A clinical trial is evaluating whether combining a cognitive rehabilitation program with a virtual reality (VR)-based aerobic exercise regimen will…
A year of treatment with the experimental BTK inhibitor fenebrutinib was safe and nearly entirely suppressed signs of disease…
Researchers uncovered a mechanism by which regulatory T-cells (Tregs), immune cells that keep the immune system in check and prevent…
Obesity promotes molecular signatures associated with more inflammation and multiple sclerosis (MS) signaling pathways specifically in females, which may…
About a third of people with relapsing-remitting multiple sclerosis (RRMS) exhibit cognitive impairments, according to a review by Australian…
Multiple sclerosis (MS) patients exhibited greater resistance to the effects of insulin — the hormone responsible for keeping the…
Measures associated with how well individuals can modulate their backward walking speed could be used as a screening tool for…
Researchers have identified characteristics of regulatory T-cells (Tregs) — a family of immune cells that help keep harmful immune reactions…
A three month cognitive rehabilitation program, with or without aerobic exercise, increased tissue volume and activity in brain regions linked…
England’s National Institute for Health and Care Excellence (NICE) has updated its guidance on the use of Mavenclad (cladribine)…
A large clinical trial to test online programs for treating fatigue in people with multiple sclerosis (MS) will…
Resistance training by middle-aged people with multiple sclerosis (MS) was linked with significant improvements in muscle strength in a…
MS Australia released a report highlighting the critical need for faster multiple sclerosis (MS) diagnoses. While diagnostic delays…
Rehabilitation approaches involving virtual reality (VR) may have beneficial effects on cognitive function and anxiety in people with multiple…
Certain biomarkers in the cerebrospinal fluid (CSF) — the fluid surrounding the brain and spinal cord — around the time…