November 19, 2014 News by Patricia Inacio, PhD Experimental Multiple Sclerosis Drug Effectively Induces Remyelination in Pre-clinical Study In a poster session at the Annual meeting of the Society for Neuroscience in Washington,Ā ENDECE Neural presented pre-clinical results showing their lead drug ā NDC-1308 ā induces remyelination in mouse models of demyelination disease, such as Multiple Sclerosis. Loss of myelin is the main characteristic of a group…
November 12, 2014 News by Patricia Inacio, PhD Use of Del-1 Protein Reduces Multiple Sclerosis Severity in Mouse Study In a study entitled āDevelopmental endothelial locus-1 is a homeostatic factor in the central nervous system limiting neuroinflammation and demyelinationā the authors report to have found a new protein, Del-1, that reduces the severity of multiple sclerosis disease in a mouse model of the disease. The…
November 11, 2014 News by Patricia Inacio, PhD Obesity Linked To Multiple Sclerosis? A team of researchers at the Tel Aviv University report the role of obesity as a major risk factor triggering and maintaining autoimmune diseases, such as Crohn’s Disease and multiple sclerosis. The study was published in Autoimmunity Reviews. In autoimmune diseases, the immune system reacts against the body…
November 4, 2014 News by Patricia Inacio, PhD MRIs are Revealing Multiple Sclerosis in Patients, Even Before Symptoms Begin A study entitled āLongitudinal Follow-up of a Cohort of Patients with Incidental Abnormal Magnetic Resonance Imaging Findings at Presentation and Their Risk of Developing Multiple Sclerosisā published in the International Journal of MS Care reports that asymptomatic patients accompanied by Magnetic Resonance Images suggestive of…
October 31, 2014 News by Patricia Inacio, PhD Neuroprotective Qualities of Masitinib Drug in Stroke Encouraging For MS Indication An encouraging experimental drug that is being developed for Multiple Sclerosis continues to show promise in being able to offer neuroprotective benefits — an effect that could slow and eventually cure MS.Ā Masitinib,Ā which is being developed by AB Science forĀ numerous neurological indications, including Alzheimer’s disease, progressive multiple sclerosis, and amyotrophic…
October 29, 2014 News by Patricia Inacio, PhD Experimental Multiple Sclerosis Drug Clears Key FDA Hurdle, To Be Tested in U.S. A new human clinical trial testing the drug ATL1102 to treat Multiple Sclerosis was approved by FDA, carrying the promise of new therapeutics to affected patients. Antisense Therapeutics Limited (ANP) announced recently in a press release the FDA’s positive decision to approve their request to submit an Investigational…
October 27, 2014 News by Patricia Inacio, PhD IGF-1 Could Suppress Immune System in Multiple Sclerosis, Other Autoimmune Disease Among autoimmune diseases, Multiple Sclerosis is one of the most progressive and debilitating, affecting between 300,000 and 400,000 people in the United States alone. The cause of the disease remains elusive to researchers, making it extremely difficult to research and develop effective therapies for treating symptoms and reversing neural…
October 23, 2014 News by Patricia Inacio, PhD Study Finds No Link Between Vaccines and Multiple Sclerosis A new study entitled, āVaccines and the Risk of Multiple Sclerosis and Other Central Nervous System Demyelinating Diseasesā published in theĀ JAMA Neurology journal, reports that no association was observed between vaccinations and an increased risk for Multiple Sclerosis or other central nervous system…
October 22, 2014 News by Patricia Inacio, PhD High Level of Multiple Sclerosis Diagnoses Observed Among Patients with Inflammatory Eye Disease The first and largest study on the association between Multiple Sclerosis (MS) and Uveitis was recently presented at the 18th annual meeting of the American Academy of Ophthalmology.Ā The meeting was held at the McCormick Place in Chicago between October 17-21, 2014. Uveitis is a disorder characterized by inflammation of…
October 21, 2014 News by Patricia Inacio, PhD Multiple Sclerosis Patients May Benefit From Use of Dorsiflexion Assist Orthotic, According To Research Much of the research and development focus for treating Multiple Sclerosis revolves around pharmaceuticals. However, the development and use of novel medical devices are also becoming a factor in treating the disease as well. A new study entitled āA dorsiflexion assist orthosis reduces the physiological cost…
October 10, 2014 News by Patricia Inacio, PhD Why NAD+ Could Become a New Multiple Sclerosis Therapy A new study entitled āNAD+ protects against EAE by regulating CD4+ T-cell differentiationā published in October issue of Nature Communications reports that NAD+ can be a future therapeutic drug to treat Multiple Sclerosis. Multiple sclerosis (MS) is a type of autoimmune disease where the inner…
October 8, 2014 News by Patricia Inacio, PhD Multiple Sclerosis Risk, Protective Factors Explored in New Research Researchers recently uncovered some curious new insights into environmental factors that may rise or lower the risk of developing Multiple Sclerosis. A new study entitled āEnvironmental exposures and the risk of multiple sclerosis investigated in a Norwegian caseācontrol studyā published in October issue of…
October 6, 2014 News by Patricia Inacio, PhD Researchers Find Link Between Multiple Sclerosis & IBD A new study entitled āIntestinal Barrier Dysfunction Develops at the Onset of Experimental Autoimmune Encephalomyelitis, and Can Be Induced by Adoptive Transfer of Auto-Reactive T Cellsā published in September issue of PloS One, reports that disruption of intestinal homeostasis supports Experimental Autoimmune Encephalomyelitis, the prototypic…
October 3, 2014 News by Patricia Inacio, PhD 159 New Multiple Sclerosis Genetic Variations Discovered By Researchers Approximately 110 multiple genetic variationsĀ were previously identified by genome-wide association studies (GWAS) to be associated with Multiple Sclerosis (MS). Now, that number has increased, with more than 159 genetic variants identified, thanks to new research presented by Philip De Jager, M.D., of Brigham and Womenās Hospital, Harvard Medical…
October 2, 2014 News by Patricia Inacio, PhD Multiple Sclerosis Patients Could Benefit From Placenta-based Cell Therapy Recent research reveals that placenta-based cell therapy is both safe and effective for treating both Relapsing-Remitting and progressive forms of MS. A new study entitled āHuman Placenta-Derived Cells (PDA-001) for the Treatment of Adults With Multiple Sclerosis: A Randomized, Placebo-Controlled, Multiple-Dose Studyā and published in August…
October 1, 2014 News by Patricia Inacio, PhD Why MS Patients Should Know What Glatiramer Acetate Therapy Is A new study, entitled āThe Effect of Glatiramer Acetate Therapy on Functional Properties of B Cells From Patients With Relapsing-Remitting Multiple Sclerosisā published online inĀ JAMA Neurology,Ā reports the effect of Glatiramer acetate therapy on B cells in relapsing-remitting multiple sclerosis (MS) patients. This first-of-its-kind study could…