Posts by: Patricia Inacio, PhD

Patricia Inacio, PhD

Patricia holds her Ph.D. in Cell Biology from University Nova de Lisboa, and has served as an author on several research projects and fellowships, as well as major grant applications for European Agencies. She also served as a PhD student research assistant in the Laboratory of Doctor David A. Fidock, Department of Microbiology & Immunology, Columbia University, New York.

August 14, 2017August 15, 2017

Phase 1 Trial Recruitment Complete for Atara’s ATA188 T-cell Immunotherapy for Progressive MS

News

Atara Biotherapeutics recently published an update of the company’s quarterly financial results and operational highlights, including the advancement of its T-cell based immunotherapy strategies for multiple sclerosis and cancer. ... Read more

August 14, 2017August 15, 2017

Human Gut Microbes May Help Suppress MS, New Research Suggests

News

A bacteria present in the gut, called Prevotella histicola, prevented multiple sclerosis from developing in a preclinical mouse model, found researchers at the Mayo Clinic in Rochester, Minnesota, along ... Read more

August 11, 2017August 14, 2017

Children and Teens with Multiple Sclerosis Consume Less Iron, Study Reports

News

Children with multiple sclerosis consume less iron, which may affect their immune and nervous systems, according to a study. Most MS cases occur between the ages of 20 and 40, ... Read more

August 10, 2017August 11, 2017

Catching the Flu Can Trigger an MS Relapse by Activating Glial Cells, Study Suggests

News

Coming down with the flu can provoke relapses in multiple sclerosis patients by activating glial cells that surround and protect nerve cells. In a study in mice, scientists found ... Read more

August 10, 2017August 11, 2017

Botulinum Toxin Treats MS Spasticity, But Support and Rehab Seen as Crucial to Long-term Use

News

Spasticity in multiple sclerosis patients can be eased through a combination of botulinum toxin type A (BoNT-A) injections and rehabilitation. However, caregiver support is required to keep patients on ... Read more

August 9, 2017August 9, 2017

India’s Advancells Reports Successful Reversal of MS in Single Patient Using Stem Cell Therapy

News

Advancells says its stem cell-based therapy completely reversed multiple sclerosis (MS) in an Indian pilot trial with only one MS patient. The patient, Rahul Gupta, was diagnosed with MS seven ... Read more

August 2, 2017August 3, 2017

24 People in Phase 1 Trial Focusing on Psoriasis Have Received KY1005, Which Is Also an MS Therapy

News

Twenty-four people have now received the multiple sclerosis and psoriasis therapy KY1005 in a Phase 1 clinical trial, according to its developer, Kymab. The Cambridge, England, company creates human antibody ... Read more

July 24, 2017July 24, 2017

Study Draws Reverse Link Between Number of a Patient’s MRI Scans a Doctor Checks and Worsened-MS Declarations

News

A new study draws a reverse link between the number of MRI scans of multiple sclerosis patients who are on interferon-beta 1a and doctors declaring there is evidence of ... Read more

July 14, 2017July 15, 2017

High Levels of Pro-Inflammatory Immune Cells in Intestines May Promote MS Activity, Study Reports

News

People with multiple sclerosis have high levels of pro-inflammatory TH17 immune cells in their intestines that correlate with change in the micro-organism mix in their gut and the levels ... Read more

July 12, 2017July 13, 2017

Antidepressant Luvox Promotes Production of Neuron-protecting Sheath in Rats, Study Shows

News

A new study on rats indicates that the antidepressant Luvox promotes the production of the neuron-protecting coating that is deficient in multiple sclerosis. It also significantly decreased the severity ... Read more

June 20, 2017June 26, 2017

Cigarette Smoking Doesn’t Speed Up Disease Progression in PPMS, Canadian Study Suggests

News

Cigarette smoking is certainly no good for you, but it may not necessarily make your primary progressive multiple sclerosis (PPMS) worse, a new study finds. The study, “Smoking does ... Read more

June 16, 2017June 16, 2017

Air Pollution May Trigger Relapses in MS Patients, French Study Finds

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Air pollution, particularly tiny inhalable particles around 10 micrometers in diameter, is a likely trigger for relapses in multiple sclerosis patients, a French study reports. The study, “Air pollution by particulate matter PM10 may trigger ... Read more

June 14, 2017June 14, 2017

Stressful Environment Triggers Inflammatory Cells Linked to Autoimmune Diseases Like MS, Study Shows

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A stressful microenvironment, characterized by low metabolites and low oxygen levels, triggers the generation of immune cells directly implicated in a variety of inflammatory diseases, such as multiple sclerosis ... Read more

June 9, 2017June 9, 2017

New Way of Growing Astrocytes from Stem Cells May Aid Research into Brain Disorders Like MS

News

Researchers at The Salk Institute have developed a way to grow vital brain cells called astrocytes from stem cells, a potential breakthrough for basic and clinical research into several diseases, including ... Read more

May 31, 2017May 31, 2017

#CMSC17 – Lemtrada’s 2 Year Therapy in RRMS Sustains Efficacy for Over 6 Years Without Additional Treatment

News

Taking Lemtrada (alemtuzumab) for two years inhibited magnetic resonance imaging (MRI) disease activity in patients with relapsing-remitting multiple sclerosis (RRMS) for more than six years, the CARE-MS I clinical trial extension ... Read more

May 30, 2017May 30, 2017

#CMSC17 – Physical Activity Halts Depression in Young MS Patients, Canadian Study Shows

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Young multiple sclerosis (MS) patients who engage in physical activity can relieve symptoms of depression, concludes a Canadian study supported by the National Multiple Sclerosis Society. Researchers presented their study, “Longitudinal ... Read more

May 30, 2017May 30, 2017

#CMSC17 – Ocrevus Lowers MS Relapse Rates Even Further in Extension Study

News

Multiple sclerosis patients who benefited from Ocrevus (ocrelizumab) in two Phase 3 clinical trials continued to benefit when they extended their treatment, researchers reported. In fact, their annual relapse rates have ... Read more

May 30, 2017May 30, 2017

#CMSC17 – Celgene’s Investigational Therapy Ozanimod Safe, Effective in Treating RMS, Clinical Trial Finds

News

Long-term treatment for up to 12o weeks, with the investigational drug Ozanimod (RPC-1063), found to be effective and safe in patients with relapsing multiple sclerosis (RMS) who participated in the ... Read more

May 26, 2017May 26, 2017

#CMSC17 – Tysabri Improves Mental Outlook for Patients with Secondary Progressive Multiple Sclerosis

News

Long-term therapy with Tysabri (natalizumab) significantly improved the mental state of people with secondary progressive multiple sclerosis (SPMS), according to results of a Biogen-supported study with patients taking the drug for ... Read more

May 26, 2017May 26, 2017

#CMSC17 – MS Mobile Apps Link Clinicians and Patients, Improving Disease Management, Study Says

News

The use of multiple sclerosis (MS) mobile apps by patients and their clinicians encourages shared decision-making and helps patients improve their outcomes, finds a study presented at the 2017 Annual ... Read more

May 26, 2017May 26, 2017

#CMSC17 – Single Session of Ball-throwing Exercise Improves Balance Control in MS, Study Shows

News

Patients with relapsing-remitting multiple sclerosis (RRMS) regain part of their balance control after a single training session of ball-throwing exercises, finds a study supported by the National Multiple Sclerosis ... Read more

May 10, 2017May 10, 2017

Increased Risk of Autoimmune Diseases Linked to Malaria-resisting Gene Variation

News

A variation in a gene that likely promoted resistance to malaria in Sardinia may have increased the risk of people there developing autoimmune diseases such as multiple sclerosis (MS) ... Read more

May 4, 2017May 4, 2017

Cytomegalovirus Infection Worsens Multiple Sclerosis, Study in Mice Shows

News

A cytomegalovirus infection triggers an increase in inflammatory and cytotoxic immune cells in mice with multiple sclerosis (MS), which leads to enhanced inflammation and loss of nerve-protecting myelin. The study, ... Read more

April 20, 2017April 20, 2017

Teva to Discuss MS and Huntington’s Therapies at Premier Neurology Conference

News

Teva Pharmaceutical Industries will discuss two of its multiple sclerosis therapies, one that reduces relapses and one that appears to protect nerve structure, at a premier neurology conference in ... Read more

April 19, 2017April 19, 2017

Sanofi Genzyme to Discuss Three Multiple Sclerosis Therapies at Boston Event

News

Sanofi Genzyme will discuss three of its multiple sclerosis therapies at the American Academy of Neurology annual meeting in Boston, April 22-28. The presentations will cover two approved treatments for relapsing MS ... Read more

April 10, 2017April 10, 2017

Ampyra Aided Walking in PPMS and RMS Patients Over Long Term, Neurologist Says in Interview

News

Ampyra (dalfampridine) shows long-term efficacy in improving walking ability in people with multiple sclerosis, according to a study evaluating the treatment’s use in progressive and relapsing MS patients over two years. ... Read more

April 10, 2017April 10, 2017

Transcript of Interview on Ampyra Research, MS Walking Ability and Long-Term Use

News

Multiple Sclerosis News Today interviewed Dr. Linard Filli,  an MS researcher at the University Hospital Zurich involved in clinical studies of prolonged release Ampyra (dalfampridine), on walking ability in MS patients, and ... Read more

April 7, 2017April 7, 2017

Exposure to Antibiotics Early in Life May Increase Risk for MS and Other Inflammatory Diseases, Study Suggests

News

The use of antibiotics in childhood, which alters the microbiome — or natural bacteria flora in the gut — may increase the risk of multiple sclerosis (MS), inflammatory bowel disease ... Read more

April 5, 2017April 5, 2017

UMD Team Reverses Paralysis in MS Mouse Model Using Novel Immunotherapy Strategy

News

Scientists at the University of Maryland have developed an experimental treatment to control the immune system and recover movement in a paralyzed mouse model of multiple sclerosis (MS). The team ... Read more

April 3, 2017April 3, 2017

Scientists Accelerate Stem Cells’ Production of Brain Cells to Just Days, Study Reports

News

British scientists have accelerated from weeks to days the process by which stem cells generate brain cells, which could open the door to new treatment approaches for diseases such ... Read more

March 30, 2017March 30, 2017

MicroRNA Therapy Restored Myelin Production, Limb Function in MS Mouse Model

News

Using a small RNA molecule belonging to the family of microRNAs (miRs), scientists could restore myelin in nerve cells and improve limb function in mouse models of human multiple ... Read more

March 20, 2017March 20, 2017

EBI2 Receptor Facilitates T-cell Invasion of Brain in MS, Animal Study Shows

News

Scientists have identified a receptor that promotes the influx of damaging immune T-cells into the brain of a mouse model of human multiple sclerosis (MS). The study, “EBI2 is ... Read more

February 27, 2017February 27, 2017

#ACTRIMS2017 – Smoking Significantly Worsens Quality of Life for MS Patients, Study Shows

News

Multiple sclerosis (MS) patients who smoke have a significantly worse quality of life than non-smoking MS patients, concludes a new study. Researchers presented the study, “Smokers with MS have greater decrements ... Read more

February 27, 2017February 27, 2017

#ACTRIMS2017 – Study Reports Possible Link Between Viral Infections, Vitamin D, and Risk for MS

News

In a U.S. nationwide case study, a team of researchers found evidence for a potential link between viral infections during childhood, vitamin D deficiency, and the risk of developing multiple sclerosis (MS). The ... Read more

February 27, 2017February 27, 2017

#ACTRIMS2017 – 60-year Follow-up Study of MS Patients Looked at Risks, Causes of Death

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A 60-year follow-up study of nearly 1,400 Norwegian patients with multiple sclerosis (MS) analyzed their survival and risk of dying starting with the onset of the disease through its progression. ... Read more

February 27, 2017February 27, 2017

#ACTRIMS2017 – Ocrevus Significantly Decreases Disease Activity in MS Patients, Study Shows

News

Ocrevus (ocrelizumab), an investigational monoclonal antibody, significantly decreases disease activity in patients with multiple sclerosis (MS), and is associated with a higher proportion of patients reaching no evidence of ... Read more

February 24, 2017February 27, 2017

#ACTRIMS2017 – There is Increased Evidence Linking Viruses to MS Risk

News

Multiple sclerosis (MS) is thought to be caused by genetic factors, but environmental cues are increasingly recognized to have an impact on disease onset and development. One environmental factor ... Read more

February 24, 2017February 24, 2017

#ACTRIMS2017 – High Salt Diet Seen as Potential Risk Factor for MS in New Study

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New evidence strengthens the link between a diet high in salt and multiple sclerosis (MS) development, researchers show. The study, “Sodium Chloride Intake and MS,” was presented on Feb. 24 at ... Read more

February 23, 2017February 23, 2017

#ACTRIMS2017 – Lemtrada Maintains Durable Positive Effects in MS Without Additional Treatment

News

Two Phase 3 clinical trials investigating the long-term effects of Lemtrada (alemtuzumab) in multiple sclerosis (MS) patients showed the drug maintained improved outcomes, even in the absence of further ... Read more

February 23, 2017February 23, 2017

#ACTRIMS2017 – Early MS Evidence Found in Asymptomatic First-degree Relatives of Patients

News

First-degree relatives of multiple sclerosis (MS) patients may develop asymptomatic disease, suggesting the need to further evaluate family members to develop timely prevention strategies. The study, “Investigating early evidence of multiple ... Read more