February 21, 2017 News by Patricia Silva, PhD Stem Cell Transplants of Greatest Benefit to RMS Patients at Earlier Disease Stages, Study Says Stem cell transplants are most effectiveĀ if doneĀ in young multiple sclerosis (MS) patients in early disease stages, who have not gone through several rounds of other treatments, according to a large study that followed transplant patients for more than five years. Study results alsoĀ found that people with relapsing MS are much…
February 20, 2017 News by Patricia Silva, PhD Ozanimod Reduces Multiple Sclerosis Relapse Rate, Phase 3 Trial Shows A Phase 3 clinical trial evaluating the safety and effectiveness of ozanimod (RPC-1063) in patients withĀ relapsing multiple sclerosis (RMS)Ā shows treatment reduced the disease’s annualized relapse rate (ARR), researchers reported. The Phase 3 SUNBEAM trial (NCT02294058)Ā testedĀ ozanimod, anĀ oral, selective sphingosine 1-phosphate 1 (S1PR1) and 5 (S1PR5) receptor modulator designed to…
February 17, 2017 News by Patricia Silva, PhD Fitness Trainer and MS Patient, Dolly Stokes, Launch BFitLifestyles Website with Husband Dolly Stokes, a fitness trainer andĀ multiple sclerosis (MS)Ā patient,Ā and her husband, Jeff Stokes, have launched the website for their fitness and wellness company,Ā BFitLifestyles, providing information on how to live an active and healthy life. The Stokes, owners of three fitness-related companies in Fairhope, Alabama ā DollyBFitness, BFitLifestyles, and Stokes…
February 17, 2017 News by Patricia Silva, PhD BpiFrance Awards PathMaker Grant to Develop MyoRegulator, Device to Treat Spasticity The French economic promotionĀ agencyĀ BpifranceĀ has awarded Boston-basedĀ PathMaker NeurosystemsĀ a grant to finance theĀ development of itsĀ MyoRegulator, a noninvasiveĀ neurotherapy technology to treatĀ conditions linked toĀ neural pathway disruption, includingĀ neuromotor spasticity in patients with multiple sclerosis (MS). Through the Programme d’Investissements d’Avenir (PIA-1), an investment program offered by Bpifrance, the Ā grant ā whose…
February 16, 2017 News by Patricia Silva, PhD AARDA Launches Registry to Help Link MS Patients, Researchers The world’s first registry for patients with multiple sclerosis (MS)Ā and other autoimmune diseases (ADs) has gone online, to honorĀ National Autoimmune Disease Awareness Month in March. The Autoimmune Research Network (ARNet) is a creation of the Michigan-based American Autoimmune Related Diseases Association (AARDA),Ā which isĀ collaborating with the National Coalition of…
February 15, 2017 News by Patricia Silva, PhD FDA OKs Bioness’ Electrical-stimulation Rehabilitation Device for Gait Impairment The U.S. Food and Drug Administration (FDA) has authorized the use ofĀ Bionessā L300 Go System electrical-stimulation rehabilitation device for multiple sclerosis (MS)Ā patients and others with walking impairment. It is the first electrical stimulation deviceĀ to offer 3D motion detection of gait and muscle activation, the company says. The L300…
February 14, 2017 News by Patricia Silva, PhD New Compound, ST266, May Prevent Optic Neuritis Linked to Multiple Sclerosis Researchers have tested a new compound called ST266 in a mouse model of multiple sclerosis (MS) and found that itsĀ anti-inflammatory properties prevent the loss of cells related toĀ optic neuritis ā a condition that leads to vision loss. The study, āIntranasal Delivery of aĀ Novel Amnion Cell Secretome Prevents…
February 14, 2017 News by Patricia Silva, PhD Cladribine Tablets Reduce Brain Atrophy in MS Patients, Merck Study Finds EMD SorenoĀ has recently published Phase 3 clinical data showing that CladribineĀ tablets reduced the annualized rate of brain volume loss (BVL, brain atrophy) compared toĀ placebo in patients with relapsing-remitting multiple sclerosis (RRMS). The study, āReduced brain atrophy rates are associated with lower risk of disability progression…
February 13, 2017 News by Patricia Silva, PhD Tongue Stimulation Could Give MS Patients Better Rehabilitation Outcomes, Study Suggests Multiple sclerosis (MS) patients given gentleĀ electrical stimulation to their tongues during physical and cognitive rehabilitation training benefited more than those who did not have the stimulation,Ā a small pilot study demonstrated. Those who received the weak stimulation had significant improvements in balance and better scores than controls in cognition and other…
February 13, 2017 News by Patricia Silva, PhD LiveWiseMS: A New Online Resource for People Living with MS AĀ new online resource, LiveWiseMS.org, aims toĀ raise awareness about multiple sclerosis (MS) and provide patients and caregivers information about the disease’sĀ symptoms and conditions.Ā The platform, developed by the International Organization of Multiple Sclerosis Nurses (IOMSN), hopes toĀ promote healthy living and improve quality of life for MS patients and their families.
February 10, 2017 News by Patricia Silva, PhD Regular Massage Therapy Eases Pain and Fatigue of MS, Small Study Reports Regular massage therapy given peopleĀ withĀ multiple sclerosis (MS)Ā significantly reduced their pain and fatigue, and helped to ease spasticity, a small pilot studyĀ reports. The results further support previousĀ findingsĀ as to the benefits of massage in treatingĀ MS symptoms and improving patients’ quality of life. The study, āImpact of Massage Therapy on Fatigue,…
February 9, 2017 News by Patricia Silva, PhD Shoe Insoles Meant to Make Walking Easier for MS Patients to Be Tested in Australia A specialty shoe insole that mayĀ helpĀ multiple sclerosis (MS) patients walk and go about their daily lives with more assurance and ease was developedĀ by an Australian-led research team, which is now seeking 176 patientsĀ to test the insoleĀ in a three-month trial. The study is led by Anna Hatton, a physiotherapy professor…
February 8, 2017 News by Patricia Silva, PhD First Multiple Sclerosis Blood Biomarker Discovered; Test May Soon Be Available Scientists have discovered the first blood biomarkerĀ for multiple sclerosis (MS) āĀ a chemical identifier in the blood. The discovery should lead to a simple blood test that makes it quicker and easier to follow the course of MS, a debilitating disease of the central nervous system affecting aroundĀ 2.3 million people…
February 7, 2017 Columns by Patricia Silva, PhD Removing Barriers to Accessibility Requires Planning, Persistence Lost in the delights of the library; 10 minutes over meter limit Yes, they chalk-marked the tires and I got a ticket. I was furious. Once again,…
February 7, 2017 News by Patricia Silva, PhD 95% of MS Patients Open to Marijuana Treatment, 73% Have Tried It Ninety-five percent ofĀ multiple sclerosis (MS)Ā patients believe medical marijuana should be a treatment option, according to aĀ GeneFoĀ online survey. The survey also showed that almost 73 percent had tried it, even though about half said they hadn’t received information from a doctor about its benefits and risks. A National…
February 3, 2017 News by Patricia Silva, PhD How MS Patients Judge Their Treatments Differs from Doctors’ Views, Study Reports Considerable differences exist in how multiple sclerosis patients, healthcare providers and insurance companies assess the value of current MS treatments, according to a literature review study by the data analysis firmĀ Real Endpoints. ForĀ the study, a team of clinicians and researchers looked at more thanĀ 300 research articles, covering topics like…
February 3, 2017 News by Patricia Silva, PhD Clinical Trial Supports Stem Cell Transplants to Treat RMS Patients with High Disease Activity A newly concluded clinical trialĀ gives scientificĀ evidence of the benefits that a stem cell transplantĀ holds forĀ multiple sclerosis (MS) patients who fail to respond toĀ medicationsĀ ā withĀ researchers calling the procedureĀ a reasonable option for thoseĀ with high disease activity. Five years after the treatment ā high-dose immunosuppressive therapy followed byĀ autologous hematopoietic cell transplant ā furtherĀ disease…
February 3, 2017 News by Patricia Silva, PhD New tDCS Devices May Boost Cognition in MS ā But Don’t Use One at Home Without Guidance Multiple sclerosis (MS) patients who received transcranial direct current stimulation (tDCS) while playing brain-training video games improved their learning and understanding skillsĀ to a greater extent than those who only brain-trained. Researchers atĀ NYU Langone’s Multiple Sclerosis Comprehensive Care Center underscored that while more research is needed to explore the procedure’s…
February 1, 2017 News by Patricia Silva, PhD Nasal Solution Made of ‘Molecular Soup’ Protects Eye Neurons in MS Mice with Optic Neuritis A treatment delivered as a nasal solution helped toĀ preserveĀ eye neurons and improve eyesight in a mouse model of multiple sclerosis (MS), a recent study demonstrated ā suggesting that it may be possible to deliver drugs that target the brain in this noninvasive way. But nasal administration is not the only…
January 31, 2017 News by Patricia Silva, PhD Patient Opinions on Zinbryta Seen to Match Phase 3 Trial Data, Supporting Questionnaire Use More relapsing multiple sclerosis (MS) patients treated withĀ Zinbryta (daclizumab)Ā said they feltĀ itsĀ health benefitsĀ than did thoseĀ givenĀ Avonex (interferon beta-1a) ā demonstrating that patient-reported outcomes do mirror objective measures of improved health in a clinical trial ofĀ the two drugs. Patient-reported changesĀ in both physical and psychological health contribute to a more comprehensive picture of…
January 31, 2017 News by Patricia Silva, PhD Tennessee Neurologist to Lead $8.4M MS Research Program at University of Saskatchewan TheĀ University of Saskatchewan‘s incoming Chair in Multiple Sclerosis Clinical Research will haveĀ a research endowment worth $8.4 million to help himĀ search for a cure forĀ multiple sclerosis (MS). The school has recruited Michael Levin, MD, an experienced MS researcher, to lead the program for a seven-year term that will begin…
January 26, 2017 News by Patricia Silva, PhD Flex Pharma Shifts Focus to Programs Targeting MS, Other Neurological Diseases Flex PharmaĀ said it plans toĀ prioritize developing its clinical programs in neurological diseases, including multiple sclerosis (MS), amyotrophic lateral sclerosis (ALS), and peripheral neuropathies like Charcot-Marie Tooth (CMT). One or two proof-of-concept, Phase 2 clinical trials are planned for this year in the United States to evaluate Flex Pharmaās…
January 26, 2017 News by Patricia Silva, PhD Genes That Influence Physical Traits May Be Reason MS More Common in Women The key to why more women than men develop multiple sclerosis (MS) may be genes that influence physical traits, such as weight, height, and body shape, according to a new study. Researchers caution that the findings need to be verified, but they said processes leading to disease may differ between…
January 25, 2017 News by Patricia Silva, PhD PathMaker, French Institute to Team on MyoRegulator Neuro-stimulation Clinical Trials PathMaker Neurosystems and the Brain and Spine InstituteĀ (ICM) in Paris will collaborate on human clinical trials to secure CE Mark clearance for PathMakerās MyoRegulatorĀ PM-2200, a noninvasiveĀ neurotherapy technology to treatĀ conditions linked toĀ neural pathway disruption, including multiple sclerosis (MS). CE Mark āĀ whichĀ stands for “ConformitĆ© EuropĆ©enne,” or European Conformity…
January 24, 2017 News by Patricia Silva, PhD University of Maryland and VA to Investigate Tregs as Possible MS Treatment The VA Maryland Health Care System (VAMHCS) and the University of Maryland Fischell Department of BioengineeringĀ areĀ collaborating in a research initiative that aims to increase our understanding of multiple sclerosis (MS). The project is being led by Christopher M. Jewell, PhD, an assistant professor in bioengineering. Jewell will…
January 23, 2017 News by Patricia Silva, PhD MS Researcher at Cleveland Clinic Awarded $7M to Pursue Ways of Stopping Myelin Damage TwoĀ Cleveland Clinic researchers were awarded multi-year grants by the National Institutes of Health (NIH), underĀ itsĀ Outstanding Investigator Award,Ā to find new treatments for multiple sclerosis (MS) and other complex diseases. Bruce Trapp, PhD, an expert in myelin biology and MS, will receive about $7 million over eight years under the…
January 23, 2017 News by Patricia Silva, PhD Astrocytes Can Turn Aggressive and Kill Neurons, Potentially Groundbreaking Study Says In what may be one of the most significant discoveries in neurodegenerative disease, researchersĀ have found that brain cells, called astrocytes, contribute to killing neurons and myelin-forming oligodendrocyte cells, which may drive neurodegenerative diseases such as multiple sclerosis (MS). Experiments indicate an aggressive astrocyte type kills cells by secreting a yet-unidentified…
January 20, 2017 News by Patricia Silva, PhD MS Patients with Spasticity Needed for Study of Extended-release Baclofen Capsules A new clinical trial evaluating the effectiveness of extended-release baclofen capsules in relieving spasticity related to multiple sclerosis (MS) isĀ calling for 135 people with any form of the disease. The study, taking place in six U.S. states, is sponsored by Sun Pharma, the drug’s developer. Baclofen, an approved MS…
January 19, 2017 News by Patricia Silva, PhD Siemens Healthineers and Biogen to Enhance MRI’s Ability to Help MS Patients Siemens Healthineers and BiogenĀ will collaborate to develop new magnetic resonance imaging (MRI) applications that can quantify key markers of multiple sclerosis (MS). āBy bringing together the shared expertise of both Siemens Healthineers and Biogen in imaging and neurology, respectively, we seek to develop new measurement tools that…
January 19, 2017 News by Patricia Silva, PhD Reports on MS Treatment Market Show Growing Shift to Oral Therapies The multiple sclerosis (MS) market shiftedĀ during 2016, with oral disease-modifying therapies (DMTs) capturing a greater share and Sanofi-Genzyme’s Aubagio (teriflunomide) being poised for growth, according to a press releaseĀ fromĀ Spherix Global Insights. The conclusions were included in the company’sĀ āRealTime Dynamix: Multiple Sclerosis,ā a quarterly report based…