The Institute for Clinical and Economic Review (ICER) has released a Draft Evidence Report evaluating the comparative clinical effectiveness and value of disease-modifying therapies (DMTs) for patients with relapsing-remitting and primary-progressive forms of multiple sclerosis (MS). Through Dec. 21, patients, the public, and other stakeholders can access the 82-page report and…
A molecule secreted by a parasite was seen to prevent autoimmune reactions in a mouse model of multiple sclerosis (MS). As this molecule, a protein factor or peptide, also worked to prevent diabetes, researchers suggest it might be developed into a potential treatment for autoimmune diseases. The study, “A parasite-derived 68-mer peptide ameliorates…
Researchers have found a way to harness inflammation with the help of ultraviolet (UV) light, making it possible to design an anti-inflammatory treatment that is more specific and causes fewer side effects. If this approach can be developed for clinical treatment, it likely will have a large impact on the lives of people with…
Royal Philips will introduce a new suite of magnetic resonance (MR)-based software applications at the upcoming Radiological Society of North America’s 102nd Scientific Meeting and Annual Assembly (RSNA 2016; #RSNA16) Nov. 27 to Dec. 2 in Chicago. Philips’ Ingenia family of digital MRI systems provides radiologists with a unique set…
Dr. Rebecca Coll, a young researcher at the University of Queensland Institute of Molecular Bioscience, won the 2016 Research Australia Discovery Award for her work in identifying promising anti-inflammatory compounds that are able to block the NLRP3 inflammasome — a key driver of inflammation. The discovery could greatly benefit patients with inflammatory diseases,…
The Multiple Sclerosis Foundation, which is celebrating its 30th anniversary this year, has launched a new website to make access to information and services easier, and a newly designed MS Focus magazine. MS Focus magazine is the foundation’s publication dedicated to common challenges, solutions, and stories of the…
Magenta Therapeutics has completed its first round of financing, raising $48.5 million to develop ways of bringing bone marrow stem cell transplants to more patients with autoimmune diseases, such as multiple sclerosis (MS), among other illnesses. The new company aims to develop the first complete platform that can overcome the challenges in stem cell transplants,…
Discovery MS, a nonprofit research initiative based at the David H. Murdock Research Institute (DHMRI) in North Carolina, had its official launch recently, and announced a series of research projects into multiple sclerosis (MS). The initiative uses private funding to advance research aiming to develop new prognostic and diagnostic tools for MS.
AXIM Biotechnologies announced that the United States Patent and Trademark Office (USPTO) will be issuing a patent covering all cannabinoids — both natural and synthetic — used in a chewing gum delivery system that may be included in its cannabinoid-containing, controlled-release chewing gum products. The USPTO has given the company a Notice of…
Quanterix and UmanDiagnostics are working to advance an assay capable of detecting neuron damage in a blood sample — a tool that could aid in the early diagnosis of multiple sclerosis (MS) and other neurodegenerative conditions. The collaboration brings Quanterix’ Simoa technology together with Uman’s antibodies against neurofilament light (Nf-L) — a…
Advances in brain imaging are making it possible to visualize early and ongoing events in multiple sclerosis (MS) — beginning with the first signs of inflammation caused by immune cells entering the brain. Should the new technique become available to physicians, it likely will not only allow for more precise diagnoses, but…
Chronic diseases like multiple sclerosis (MS) not only impact patients, they also inspire fear among healthy people who may be at risk of the disease. In a new study, researchers found that the availability of multiple sclerosis (MS) therapies provides “peace of mind” value to currently healthy individuals, particularly when…
Researchers in Russia found for a first time an association between variants in GAL, a gene that codes for the galanin protein, and multiple sclerosis (MS). Importantly, they also found that this association is sex specific. The study, “Single-nucleotide polymorphism rs948854 in human galanin gene and multiple sclerosis: a…
The British government announced on Oct. 31 that a new Personal Support Package will be available for people with health disabilities, such as multiple sclerosis (MS), ensuring they receive personalized health and employment support. A Green Paper – a government document for consultation – is available online to open…
In multiple sclerosis (MS) patients who do not respond to interferon-beta treatment, autoimmunity may depend on processes that differ from patients helped by this treatment— a finding that could lead both to better therapies and tests that predict a patient’s likely response. The study, “An interferon-β-resistant and NLRP3…
Researchers at McGill University Health Centre (MUHC) in Canada developed a new tool to diagnose cachexia — also called wasting syndrome. It’s characterized by weight loss, muscle atrophy, fatigue, weakness, and a significant loss of appetite in someone who is not trying to lose weight, mainly in cancer patients. The tool may also…
A cost-effectiveness analysis of reimbursement recommendations for four relatively new multiple sclerosis (MS) treatments made by agencies in four countries — Australia, Canada, Sweden, and the U.K. — found overwhelming support (88 percent) for either full or restricted reimbursement for each therapy. The analysis, performed by the Decision Resources Group, is…
Medical Marijuana announced that Axim Biotechnologies, a cannabinoid-based product developer in which it owns a strategic interest, has released a product pipeline chart highlighting development timelines for its cannabinoid-based therapeutics, including those for multiple sclerosis (MS) patients. The chart illustrates the stage each drug is in, from preclinical testing to, eventually, applications for regulatory…
The National Disability Institute manages the website www.ablenrc.org that has good information. I watched all the “webinars” and found them informative. A new one is going to be broadcast Nov. 15, 1:00-2:30 CST (event number 660 742 928), and likely will be archived with the rest of the webinars…
A large international research effort concluded that the geographical area where a person lives affects how early they will start showing symptoms of multiple sclerosis (MS), and that people living in the more northern regions having the earliest disease onset. The age at which a person fell ill also was…
Dr. Daniel Reich, a researcher with the National Institutes of Health (NIH), has been recognized for his pioneering work on brain imaging to advance both the treatment of people with multiple sclerosis (MS) and scientific understanding of the disease. Reich, a neurologist, neuro-radiologist and neuroscientist, was awarded the 2016 Barancik Prize for Innovation in MS…
ABLE Accounts and Amendments In my previous column, I introduced the exciting new program for people with disabilities, called the ABLE Act (Achieving a Better Life Experience Act). The final bill, signed into law in 2014, deviated substantially from the original proposal and that needs to…
Immunization with molecules present specifically in myelin may be a new approach to treating multiple sclerosis (MS), according to a recent study that found that the mouse version of such molecules could stop ongoing disease processes in an MS mouse model. The study, “Targeting Non-classical Myelin Epitopes to Treat…
The Multiple Sclerosis Foundation, celebrating its 30th anniversary of serving the multiple sclerosis (MS) community, will host the Bourbon and Blues black tie gala on Saturday, Dec. 3, at the Ritz-Carlton in Fort Lauderdale, Florida. Cocktail hour will start at 6:30 p.m., and 8:00 p.m. brings the…
GNS Healthcare is presenting a data-driven causal machine learning solution, called Efficacy to Effectiveness, designed to predict how potential therapies will actually perform in distinct populations. The data, being released today at ISPOR 2016, used pre-launch data from a study comparing Gilenya (fingolimod) and other multiple sclerosis (MS) therapies to build and validate causal models…
Helius Medical Technologies‘s Portable Neuromodulation Stimulator (PoNS), a device being developed to treat neuroplasticity in people with multiple sclerosis (MS) and other neurological diseases, has been recommended for ISO 13485 certification, an international standard of quality management for medical devices, after a positive evaluation by Lloyd’s Register Quality Assurance Limited (LRQA). This…
AXIM Biotechnologies announced it has secured financing from private sources to continue its testing of medical cannabinoid products as potential treatments for multiple indications, including pain and spasticity in people with multiple sclerosis (MS). Specifically, AXIM is testing pharmaceutical delivery systems and active ingredients for its medical marijuana line. “This financing provides us with…
Getting more African-Americans and other minority groups to take part in clinical research into treatments for multiple sclerosis (MS), and identifying and tackling continuing disparities in efforts that affect patient care, will be the focus of a project led by the nonprofit group Accelerated Cure Project for Multiple Sclerosis (ACP) and supported…
Selexis has entered into a commercial arrangement with ImmuNext, providing that company with access to research cell banks from its SURE technology Platform (a best-in-class cell line development technology). ImmuNext will use the cell banks in further developing its anti-CD40 ligand antibody, a potential therapeutic agent for chronic autoimmune disorders such as multiple sclerosis…
Columbia Care announced the launch of its line of pills for medical marijuana — calling it the first controlled-dose, pharmaceutical-quality and solid-fill medical cannabinoid capsule available to people with prescriptions for medical marijuana use in the U.S. The New York State Department of Health recently approved the capsule line, in…
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