Urinary Tract Symptoms Found to Affect 70% of MS Patients in Study and Contribute to Disability
Urinary tract symptoms affect a large proportion of patients with multiple sclerosis (MS), yet their extent and type is not…
Articles by Patricia Silva, PhD
MedDay Raises $38.5M to Finance Phase 3 Trial Targeting Progressive MS
MedDay SAS recently announced that it has raised €34 million, about $38.5 million, in a Series B financing round. The…
Natalizumab (Tysabri) Targets Molecule Crucial for Type of B-Cell to Accumulate in the Brain
Mice with experimental autoimmune encephalomyelitis (EAE), an animal model of multiple sclerosis (MS), were found to have milder symptoms if…
National MS Society Invests $25.3M to Support 60 New Research Projects, Train Clinicians
The National Multiple Sclerosis Society announced that it has invested $25.3 million to support nearly 60 new research projects aiming to better…
MS Patients Asked to Take Part in Survey of Risk/Benefit Considerations in Choosing Treatments
The National Multiple Sclerosis Society is funding a new survey to understand how people living with multiple sclerosis (MS)…
Doctors Study Possible Link Between Dimethyl Fumarate (Tecfidera) and Shingles
A case report of a woman with relapsing-remitting multiple sclerosis (RRMS) who developed shingles while being treated with dimethyl fumarate…
Colorado Neurological Institute to Host ‘Spotlight on Hope’ Gala and Fundraiser on April 15
The Colorado Neurological Institute (CNI), a non-profit research and neurological care organization, will host the “Spotlight on Hope” gala and fundraising event on…
MS-associated Myelitis Can Be Identified Early Through MRI Scans, Study Reports
Researchers reported that patients with myelitis who later develop multiple sclerosis (MS) might be distinguished from others with myelitis by…
New Clinical Trial Data on Experimental MS Therapeutic Vaccine, Xemys, Released
PJSC Pharmsynthez, a pharmaceutical company based in Russia, recently announced completed follow-up findings and data analysis from a Phase…
Young MS Patients in the US More Likely to Be Overweight and Suffer More Relapses Than Peers Elsewhere, Study Finds
Scientists at the Pediatric MS Center at NYU Langone, New York, reported that U.S. adolescents with multiple sclerosis (MS) receiving interferon-beta…
MS Therapy Tecfidera Might Exert its Actions by Increasing Specific B-cells
Editor’s note: The term B-cells is, in fact, a collective term for a group of cells having rather different properties.
Signaling Molecule Seen to Induce CNS Remyelination in Mice with Spinal Injuries
Neuregulin-1 is a signaling molecule of interest in the context of synaptic plasticity — the ability of our nerve cells to…
Alemtuzumab (Lemtrada) Seen to Slow Disease Progression by Targeting Key Brain Systems
Several clinical trials have shown that alemtuzumab (Lemtrada) effectively reduces relapse rates in patients with multiple sclerosis (MS), and improves disability…
National MS Society Welcomes Novartis as Premier Sponsor, for 5th Year, of Walk MS
The National Multiple Sclerosis Society is welcoming Novartis Pharmaceuticals, for a fifth consecutive year, as a leading national sponsor of…
MS Relapses During Natalizumab Therapy Traced to Drug’s Greater Impact on Regulatory T-cells
Natalizumab (Tysabri) harnesses multiple sclerosis (MS) activity by targeting CD49, a molecule on the surface of immune cells. Now, researchers…
MS Survey Reviews How Patients Perceive Diet, Exercise and Drug Treatments
A survey, summarizing the views of 2,600 multiple sclerosis (MS) patients, showed how people manage their disease in real life…
Rosacea Appears to Be Linked to Multiple Sclerosis in Women, Study Reports
Rosacea is an inflammatory skin condition affecting mostly fair-skinned individuals. A study from the University of Copenhagen, Denmark, recently…
Potential Progressive MS Treatment, Ibudilast, Approved for Fast Track Development by FDA
MediciNova, Inc., announced that MN-166 (ibudilast) has been approved for “fast track” development by the U.S. Food and Drug Administration (FDA) as…
High Lactate Levels in MS Patients Tied to Disease Progression, Mitochondrial Dysfunction
Scientists in recent years have wondered whether a link exists between high lactate levels resulting from mitochondrial dysfunction and multiple sclerosis (MS) progression.
Ethnic Study of East Londoners with MS Highlights Role of Environment in Disease Onset
According to new research published in the Multiple Sclerosis Journal, environmental factors appear to play a much greater…
CONy16: Pros and Cons of MS Drugs Targeting Immune Cells Other Than B-cells Debated
Clinical trials have shown that ocrelizumab — an antibody targeting B-cells — is effective in multiple sclerosis (MS). As a…
CONy16: Should RRMS Disease-Modifying Drugs Be Used to Treat Secondary Progressive MS?
A major dilemma facing clinicians is whether to continue treatment with disease-modifying drugs, effective in relapsing-remitting multiple sclerosis (RRMS), as the disease…
CONy16: Sanofi Genzyme Symposium on MS Therapies Targeting T and B Cells; Exclusive Interview with Lead Researcher
Sanofi Genzyme, one of the companies participating in the four-day 10th World Congress on Controversies in Neurology (CONy) in Lisbon, Portugal, that concluded on…
CONy16: Debate Weighs MS Therapy Risks of Infections Like PML in Terms of Benefits Offered
Certain therapies used to treat multiple sclerosis (MS) have been associated with opportunistic infections of the central nervous system, including progressive…
#CONy16: Can Vitamin D Be Considered a Disease Modifier for Multiple Sclerosis?
Vitamin D is crucial for our general health and it is known that it modulates immune responses. While large studies have…
#CONy16: Scientists Debate MRI’s Role in MS Treatment Changes; Exclusive Interview with Prof. Xavier Montalban
The precision of magnetic resonance imaging (MRI) measurement has improved over the years, and now scans can identify brain damage…
Blood Biomarkers of Multiple Sclerosis May Predict a Person’s Response to Treatment
Blood biomarkers in individual multiple sclerosis patients may help clinicians determine which treatments would be of most benefit to that person, according to researchers at Oklahoma…
Virtual Reality Balance Training in RRMS Patients Shows Benefits in Small Study
Interventions to improve balance in patients with multiple sclerosis (MS) have produced varying results, but a small clinical trial showed…
Immune Cells in Brain Seen to Promote Cognitive Impairment In MS Mouse Model
Microglial cells in the hippocampus, a brain region crucial for memory processing, may contribute to brain damage associated with cognitive impairment…
People with MS, Especially Men, Likely to Have Other Chronic Health Conditions
People newly diagnosed with multiple sclerosis (MS) tend to also suffer from other chronic health problems, particularly depression, according to…