Rituximab Seen to Affect How B-cells Return After Treatment Stops
Rituximab, an investigational B-cell depletion therapy that target CD20 to treat people with multiple sclerosis (MS), has significant effects…
Articles by Steve Bryson, PhD
Altered Gut Microbiome, Metabolism Found in Japanese RRMS, SPMS Patients, Study Reveals
Alterations in gut bacteria and bacterial metabolism were found in Japanese people at different stages of multiple…
Immune T-cells Trigger Early MS Inflammation, Twin Study RevealsÂ
A comparison of immune cells isolated from identical twins — in which only one of each pair was…
Ocrevus Cancels RRMS Patient’s Immunity to Chickenpox Virus, Case Study Finds
Ocrevus (ocrelizumab) eliminated the immunity, acquired through vaccination, to the varicella-zoster virus — the virus…
Gsta4 Protein Promotes Myelin Repair, Prevents Symptoms in MS Rat Model
A protein known as Gsta4 is critical in the growth and activity of oligodendrocytes, a special type of…
Inflammation Drives Nerve Damage in Early MS, Imaging Study Shows
Inflammation drives the loss of brain volume and thinning of the eye’s retina in the first five years…
Immune Cell Protein CD36 Shows Potential as Therapeutic Target, Study Suggests
For the first time, scientists have shown that a protein known as CD36 on the surface of some…
Smoking and Epstein-Barr Virus Combine to Raise MS Risk, Study Says
Cigarette smoking and an Epstein–Barr virus infection together represent a significant risk factor for multiple sclerosis (MS), suggesting…
Protein Linked to Inflammation in MS Also Helps to Control It, Study Finds
The pro-inflammatory signaling protein interleukin (IL)-17A, which is associated with nerve damage in multiple sclerosis…
HLA-DPB1 Gene Variants May Influence MS Onset and Relapse Risk
A variant of the HLA-DPB1 gene — called HLA-DPB1*04…
Special Exercise App Wins Favor in Progressive MS Study, But Little More
A multimedia smartphone application designed to precisely inform about exercise and track physical activity led primary…
Anxiety and Depression Linked to RRMS Relapse Risk, Study Finds
Comorbidities such as anxiety and depression are associated with a significantly increased risk of relapse in people with…
More Research Needed Into How Exercise, Rehab Aid Cognition in MS
Cognitive problems are common in people with multiple sclerosis (MS) but inadequately addressed by disease-modifying therapies, while cognitive rehabilitation and…
Immune Cells Reprogrammed in Mice May Lead to Potential MS Treatment, Study Suggests
After repeated exposure to a fragment of the myelin protein — the target of autoimmune attack in multiple…
Higher Risk of Vascular Disease Among MS Patients in the UK, Population-based Study Reveals
People in the United Kingdom (U.K.) with multiple sclerosis (MS) have an increased risk of vascular disease affecting the…
Immune Cell microRNAs Are Potential MS Biomarkers, Study Suggests
Altered levels of molecules important for cell regulation — called microRNAs — have been found in specific immune…
FDA Approves Bafiertam, Tecfidera Bioequivalent, for Relapsing MS
The U.S. Food and Drug Administration (FDA) has given final approval to …
Inflammation, Blood Fats Linked to Cardiovascular Disease in MS
Scientists have identified a link between systemic inflammation and fat (lipid) metabolism that may underlie the increased risk…
Gray Matter Lesions Affect Cognition in Japanese MS Patients as Well, Study Says
People in Japan with lesions in the cerebral cortex due to multiple sclerosis (MS) were found to have…
Age, Gender, Blood Glucose Affect Immune Cells’ Response to Tecfidera in RRMS Patients, Study Reports
Immune cells from patients with relapsing-remitting multiple sclerosis (RRMS) respond differently to Tecfidera…
Gilenya Works to Treat RRMS by Specifically Targeting B-cells and T-helper Cells, Study Finds
Treating people with relapsing-remitting multiple sclerosis (RRMS) for one year with the immune-modulating…
Ethnic Differences in MS Evident in Antibody-secreting Cells in Blood, US Study Suggests
People with multiple sclerosis (MS) who self-identify black African or Latin American have a higher number of…
Specific Changes in Vitamin D Receptor Protein Linked to MS Risk, Study Suggests
A risk of multiple sclerosis rises in people with specific variations in a protein, called…
Gut Microbiome Changes Evident in Newly Diagnosed MS Patients, Study Says
A DNA analysis to identify changes in the gut microbiome in people newly diagnosed with multiple…
Blocking Molecule Prevents B-cells from Entering Brain and Promoting MS Progression, Study Reports
Stopping the migration of immune B-cells through the blood-brain barrier by blocking ALCAM, a molecule linked to the…
UV-B Light Prevents MS Symptoms in Mice Independently of Vitamin D, Study Finds
Exposure to UV-B light prevented multiple sclerosis (MS)-like symptoms in a mouse model regardless of the presence…
Altered Fear Response, Changes in Brain Chemistry Seen in Mice with Poor Gut Microbiota
Depleting microbes in the gut of mice led to an altered fear response, changes in gene expression in…
SPMS Triggers and Treatments Among Focus of Expert Panel in Video Series by AJMC
Multiple sclerosis (MS) experts discuss disease causes and current treatment options in a new video…
MS Relationships Improved by Togetherness and Communication, Study Suggests
Relationships between multiple sclerosis patients and their intimate partners were enhanced when the couple worked together to make lifestyle changes, and to develop skills to improve communication, a study shows.Â
Rewind Therapeutics Receives Research Grant to Develop New Remyelination Medicines for MS
The development of new medicines to treat myelin-related neurological diseases, such as multiple sclerosis…