News

Kinase Inhibitor, Masitinib, Spotted for Potential to Treat Neurological Disorders Like PPMS

AB ScienceĀ recently reported the publication of four peer-reviewed and independent research papers that add to the growing recognition of masitinib, the companyā€™s lead compound, as a promising treatment for neurological and neurodegenerative diseases, including progressive multiple sclerosis (MS), Alzheimerā€™s disease (AD), and amyotrophic lateral sclerosis (ALS). Tyrosine kinase inhibitors (TKIs)…

European Regulatory Agency Finds Gilenya Not of Added Benefit to Certain RRMS Patients

A newĀ assessment by a European regulatory agency failed to findĀ fingolimod ofĀ added benefitĀ to comparator therapiesĀ for peopleĀ with highly active relapsing-remittingĀ multiple sclerosis (RRMS) who have failed to respond toĀ treatment with at least one other disease-modifying drug. Fingolimod (Gilenya), developed as a therapy for multiple sclerosis, has undergone three early benefit assessments since its…

Can Playing Video Games Reduce MS-induced ‘Brain Fog’?

Video games targeting cognitive abilities may improve brain function in patients with multiple sclerosis (MS), a new study found. Results, published in the journal Radiology, showed that these games strengthen connections between neurons in the thalamus, a brain region crucial for information processing. The findings alsoĀ add to…

#MySupportHero Program Celebrates MS Caregivers in All Walks of Life

To celebrate the many family, friends, healthcare professionals, and advocacy communities offeringĀ vitalĀ support to people living with multiple sclerosis (MS)Ā day after day,Ā MSWorld and Biogen have created the #MySupportHero program. The social media campaignĀ runs through March, MS Awareness Month, to allowĀ people with MS toĀ thank all those who encourage and…

Damage to Nerve Synapses in MS Mouse Model Found to Be Unrelated to Myelin Destruction

ResearchersĀ found that nerve cell connections in the brain, called synapses, wereĀ damaged in aĀ mouse model ofĀ multiple sclerosis (MS) through a process wholly unrelated toĀ myelin destruction. As the damaged mice synapses studied were inĀ regions crucial for memory processing, findingĀ ways of protecting these neurons would be a crucial step toward developing a…

Kessler Foundation MS Researcher Awarded $70,000 Fellowship to Investigate Cognitive Function

Silvana L. Costa, PhD fromĀ the Kessler Foundation,Ā wasĀ recently awarded a Switzer Research Fellowship by the National Institute on Disability, Independent Living and Rehabilitation Research (NIDILRR). Dr. Costa is a Hearst Fellow in Neuropsychology & Neuroscience Research at Kessler, where she investigates cognitive deficits in multiple sclerosis (MS). The Merit Fellowship,…

Science Foundation Awards to Further Work into Rehabilitative Robotics, Online Tools at Northwestern University

Two scientists atĀ Northwestern University,Ā Anne Marie Piper and Brenna Argall, recently received the Faculty Early Career Development (CAREER) Award from theĀ National Science FoundationĀ (NSF). The work of Dr. Argall, in particular, might be relevant for peopleĀ with disabilities caused by diseases such as multiple sclerosis or brain trauma resulting from accidents…

National MS Society Names Childrenā€™s Health of North Texas a Comprehensive MS Care Center

Childrenā€™s HealthĀ of North TexasĀ has been designatedĀ Ā a Center for Comprehensive MS CareĀ by the National Multiple Sclerosis Society, making it the only pediatric healthcare system in the northern part of the state with such a recognition. The Comprehensive MS Care designation acknowledgesĀ an institutionĀ that delivers quality, full patient care in a…

Therapeutic Target for Stabilizing Histamine, an Inflammatory Agent in MS, Identified in Fruit Fly Study

Researchers at the University of Massachusetts Medical School, workingĀ in the fruit fly model,Ā identified an organic cation transporter, CarT (carcinine transporter), that is crucial to the recycling of histamine in the brain and the maintenance of healthy vision. Histamine is a neurotransmitter involved in chronic inflammation and pathogenesis in multiple…

MS Progression Apparently Not Affected by Number of Pregnancies, Study Reports

New long-term research indicates that having multiple children does not lessen or otherwise impact disability in women with multiple sclerosis (MS).Ā The study, titled “Offspring Number Does Not Influence Reaching the Disabilityā€™s Milestones in Multiple Sclerosis: A Seven-Year Follow-Up Study,“Ā was published in The International Journal…

MS Gait Analysis Identifies 2 New and Highly Sensitive Markers of Disability and Fatigue

Researchers analyzingĀ gait in people with multiple sclerosis (MS) usingĀ wearable inertial sensors have established two newĀ and highlyĀ sensitive observer-independent measures of disability that strongly correlate with fatigue and patient-perceived health status. Their article, titled ā€œDisability and Fatigue Can Be Objectively Measured in Multiple Sclerosis,ā€ was published in the journal PLOS…

Biogen’s ‘1MSg Campaign’ Encourages MS Patients to Better Manage Their Disease, Engage with Specialists

BiogenĀ is launching an initiative developed with the assistance of clinical experts ā€” the 1MSg campaignĀ ā€”Ā to educate and encourage multiple sclerosis (MS) patients to make disease management decisions that are well-informed andĀ basedĀ onĀ the latest scientific research. The campaignā€™s motto is ā€œTake control, known your choices,ā€ and one of its main…

Relapsing MS Treatment Showing Efficacy in Phase 2 Extension Study, Celgene Reports at ACTRIMS 2016

Celgene CorporationĀ announced theĀ results from anĀ extension studyĀ of theĀ RADIANCE Phase 2 clinical trial evaluating ozanimod in patients with relapsing multiple sclerosis (MS). The results were also presented at the recentĀ Americas Committee for Treatment and Research in Multiple Sclerosis (ACTRIMS) Forum 2016Ā in New Orleans, Louisiana. Ozanimod is a small…