Tamoxifen (brand name, Nolvadex), a widely used treatment for breast cancer, can also be used to treat myelin loss in patients with multiple sclerosis (MS), a new study suggests. The finding, by a team of researchers at the University of Cambridge, U.K., was published in a study titled “…
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A study exploring the difficulties parents experience when their child develops multiple sclerosis (MS) found that more support and education — from healthcare and school staff, as well as by parents themselves — is key to easing the burden of a child or teenager with this disease. The study, “Parents’…
The Conrad N. Hilton Foundation announced that nominations are now being accepted for the Marilyn Hilton Award for Innovation in Multiple Sclerosis Research. The award aims to stimulate new and potentially groundbreaking research into progressive multiple sclerosis (MS), and the Foundation expects to distribute to $4 million in grants over five years, supporting the…
Paralyzed Veterans of America recently held its annual health conference, called 2016 Summit + EXPO, focused on the latest research and discoveries in patient care for diseases that span multiple sclerosis and spinal cord injury or disease to amyotrophic lateral sclerosis. This year was the sixth such summit, held Aug. 30–Sept. 1 in Orlando, Florida,…
To reach tissues infected with foreign agents, neutrophils, the body’s first line of defense, need to travel through vessel walls — and do so by switching on a class of adhesion receptors, called integrins, that bind to other adhesion molecules at the surface of the capillary walls. Now, in a recent paper published…
More than 900 people biked through the Mauricie region of Quebec, Canada, late last month, raising money for the Quebec Division of the Multiple Sclerosis Society of Canada (MSSC) and awareness for multiple sclerosis (MS) all-around. The 27th Medavie Blue Cross MS Bike, the largest cycling-related fundraising event in North America, was an outstanding success — surpassing…
Multiple sclerosis patients are at risk of developing lymphopenia, or abnormally low levels of immune defense white blood cells, called lymphocytes, according to a study that investigated lymphocyte counts in people with relapsing MS both before and after the start of treatment. The study, “Lymphopenia in treatment-naive relapsing multiple…
Previous studies have pointed toward certain lifestyle factors such as nutrition, sedentary behavior, and stress as possible key determinants in multiple sclerosis (MS) progression but few studies have been dedicated to learning more about the impact of lifestyle risk factors on patient disability and disease progression. A recent study supports the…
RegeneRx Biopharmaceuticals announced that it has received an Intent to Grant notice from the European Patent Office (EPO) regarding a patent for its proprietary molecule Thymosin beta 4 (Tβ4), a potential therapy for multiple sclerosis (MS) designed to promote remyelination. The patent will cover the use of Tβ4 in a composition for treating or reducing…
The European Patent Office has released a Notice of Intention to Grant a new patent to support RHB-104 as a therapy for relapsing-remitting multiple sclerosis (RRMS). RHB-104 is being developed by RedHill Biopharma. Patents covering the use of RHB-104 exist in over 25 countries, including the U.S., Australia, Canada, Japan, and in…
The U.S. Food and Drug Administration (FDA) has designated TG-1101 (ublituximab), a glycoengineered anti-CD20 monoclonal antibody by TG Therapeutics, an orphan drug to advance its development. The drug is a potential treatment for neuromyelitis optica (NMO) and neuromyelitis optica spectrum disorder (NMOSD), two relapsing-remitting autoimmune diseases with similarities to multiple sclerosis. Currently, there are…
Here’s my Pick of the Week’s News, as published by Multiple Sclerosis News Today. Umbilical Cord Blood-derived Cell Therapy Promotes Remyelination in Mice Now this is different, using umbilical cord stem cells. A cell therapy product derived from human umbilical cord blood cells may be…
The Government of New Brunswick added Lemtrada (alemtuzumab), by Sanofi Genzyme, to the New Brunswick Prescription Drug Program (NBPDP) through special authorization for eligible patients with relapsing-remitting multiple sclerosis (RRMS). New Brunswick joins other Canadian provinces, including Ontario, Saskatchewan, Quebec, and Manitoba, in making this treatment available to RRMS patients, ages 18 and older, who have had…
Patients with secondary progressive multiple sclerosis (SPMS) who were treated with BAF312 (siponimod), a sphingosine-1-phosphate (S1P) inhibitor, in a Phase 3 clinical trial showed a significantly reduced risk for disability progression compared to placebo, Novartis recently announced. BAF312 is a selective modulator of specific types of the S1P receptor. This receptor is…
The Quebec Division of the Multiple Sclerosis Society of Canada (MSSC) announced that this year’s 27th Medavie Blue Cross MS Bike, a fundraising bike ride on roads alongside St. Lawrence River, will take place Aug. 27 and 28 in the Mauricie region. A total of 900 cyclists are set to participate in…
The National Multiple Sclerosis Society announced that it has dedicated more than $1 million to support a clinical study at the University of Iowa that will compare two types of diet and their effectiveness in easing fatigue in people with multiple sclerosis (MS). “The National MS Society is committed to identifying wellness solutions to…
Health Canada has approved Teva Canada Innovation‘s three-time weekly 40 mg/mL injection of Copaxone (glatiramer acetate) that allows less frequent dosing for patients with relapsing-remitting multiple sclerosis (RRMS). The approval was grounded primarily on data resulting from the Phase 3 Glatiramer Acetate Low-Frequency Administration (GALA) study, the largest Copaxone clinical…
An innovation in multiple sclerosis (MS) research has been launched by the iConquerMS initiative — a longitudinal, prospective study called “REAL MS,” an acronym for “Research Engagement About Life with Multiple Sclerosis,” with a goal of accelerating research into personalized treatments for MS patients. This type of study collects repeat…
Multiple sclerosis seems to be less severe in people with higher levels of the minor adult hemoglobin variant A2 (HbA2) in their blood, according to a team of Turkish researchers. This could be due to this variant having a higher protective effect on the red blood cell membrane. The authors speculate that HbA2 could therefore be playing a role in reducing long-term neural injury in MS.
People with relapsing multiple sclerosis who use a device called RebiSmart (Merck Serono) to self-inject medications like Rebif (interferon [IFN] beta-1a) are more likely to take their therapies on a regular schedule and adhere to that schedule, resulting in fewer relapses than those not using the device, according to a retrospective study by researchers…
In the two years following my diagnosis, I had many bouts of chest pain, breathing difficulties, and sharp stomach pains. I worried that some other terrible illness was right around the corner. Four EKGs, three ultrasounds, two pulmonary function tests, and one colonoscopy later I had a surprisingly good bill…
A new video series for multiple sclerosis patients in the U.S. looks to help them better understand the complex legal and planning issues they face. The series, put together by the National Academy of Elder Law Attorneys (NAELA) and Stetson University College of Law, in consultation with the National Multiple Sclerosis Society, is…
General practitioners (GPs) in England lack confidence in initially assessing and referring onward people with neurological symptoms, especially those with multiple sclerosis, and believe they could benefit from better training in identifying and managing neurological patients. One result, according to a report published by the Neurological Alliance, titled “Neurology and primary care: improving the…
Here’s my Pick of the Week’s News, as published in Multiple Sclerosis News Today. Blood Test Seen to Distinguish MS from Other Neurological Conditions A faster way to tell the difference between neurological diseases could mean earlier access to treatment for MS patients. Researchers at Michigan State…
A&W Food Services of Canada is celebrating its “Burgers to Beat MS” day on Thursday, Aug. 25, and for an 8th year will donate $1 for each Teen Burger sold at any of its 860 restaurants nationwide to the Multiple Sclerosis Society of Canada (MSSC). Through such campaigns, A&W has raised over $8 million since 2009…
A cell therapy product derived from human umbilical cord blood cells may be a promising treatment approach for patients with demyelinating diseases, such as multiple sclerosis (MS) or leukodystrophy, according to a recent study developed at the Duke University Medical Center. The study, “A cord blood monocyte–derived cell…
Researchers at Michigan State University suggest that a blood test can distinguish patients with multiple sclerosis (MS) from people with other neurological conditions, according to a recent study published in EBioMedicine. Results from the study, “An In Vitro Diagnostic for Multiple Sclerosis Based on C-peptide Binding to Erythrocytes,”…
Relapsing multiple sclerosis patients who begin taking Betaferon/Betaseron (interferon beta-1b) immediately after the first MS-related neurologic symptoms appear may realize slower disease progression than those who delay treatment, according to a study evaluating the therapy’s effects over a decade in patients enrolled in a Phase 3 clinical trial. The study, “The 11-year long-term follow-up…
There are several key questions that a participant will want answered before enrolling in a clinical trial. Many are listed here, but patients should feel free to ask study coordinators any additional questions they may have so their concerns are well addressed before the trial starts. It is important for a study participant to learn as…
Researchers from Colorado State University propose a new model of fatigue in multiple sclerosis (MS), designed to overcome the lack of a unified definition of fatigue that can be objectively tested using experimental approaches. With this model, the authors behind the article, “Fatigue in Multiple Sclerosis: Misconceptions…