Can Vitamin D Supplements Prevent MS or Keep Symptoms from Worsening?

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Vitamin D supplements and MS

There has been a great deal of talk and conjecture about the relationship between multiple sclerosis (MS) and vitamin D, often linked to living in an area lacking sunshine. Indeed, when I lived in the United Kingdom, which is notorious — or should be — for seemingly endless gray skies and rain, my MS specialist nurse recommended that I take a vitamin D supplement.

I never did but went one better: My wife Lisa and I moved to Andalucía in the south of Spain. There we have enough sunshine to satisfy all my vitamin D needs.

So what do we know about MS and vitamin D?

“A study conducted by researchers at the U.K.’s University of Oxford and another conducted at the New Jersey Medical School have both suggested that maintaining adequate levels of vitamin D may have a protective effect and lower the risk of developing multiple sclerosis (MS),” said Dr. Jerry Swanson, a neurologist at the Mayo Clinic in Rochester, Minnesota.

“Another study, conducted at Maastricht University in the Netherlands, and others, suggest that for people who already have MS, vitamin D may lessen the frequency and severity of their symptoms.

“But more research is needed to assess these findings,” Swanson said.

Vitamin D Has a Positive Effect

We know that when people have MS, their immune system attacks the myelin coating that protects the nerve cells.

“Research suggests that a connection between vitamin D and MS could be tied to the positive effects vitamin D has on the immune system,” Swanson said.

“The link between vitamin D and MS is strengthened by the association between sunlight and the risk of MS. The farther away from the equator a person lives, the higher the risk of MS. Sunlight is the body’s most efficient source for vitamin D — suggesting that exposure to sunlight may offer protection from MS,” he added.

Just what my MS nurse was saying when he urged me to take a supplement.

I am not going to go into the levels of supplements that people with MS might take to feel some benefit. That is a medical matter and is something to discuss with your doctor.

One word of caution, though. Swanson warns that very large doses of vitamin D over an extended period can result in toxicity. Signs and symptoms include nausea, vomiting, constipation, poor appetite, weakness, and weight loss. In addition, vitamin D toxicity can lead to elevated levels of calcium in your blood, which can result in kidney stones.

Dr. Jerry W. Swanson is a board-certified neurologist at Mayo Clinic in Rochester, Minnesota. He is also board certified in headache medicine and is a professor of neurology at College of Medicine, Mayo Clinic. He has a special interest in medical education.

Swanson, native of Lacon, Illinois, was appointed to the Mayo Clinic staff in 1982 and works in the Department of Neurology with more than 90 other physicians. He formerly chaired the department’s Division of Headache and continues to work with headache sub-specialists around the world. He has published and lectured widely on headache disorders. He also serves as assistant dean for assessment at Mayo Medical School.

Note: Multiple Sclerosis News Today is strictly a news and information website about the disease. It does not provide medical advice, diagnosis, or treatment. This content is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. Never disregard professional medical advice or delay in seeking it because of something you have read on this website.


Marilyn Roberts avatar

Marilyn Roberts

Please give more info/findings about Rituxin as yesterday was my 2nd initial dose! Thanks!



Sun exposure for all patients ? Even those with outbreaks in the cervical spine or the thorax ?


Vitamin D supplements may be the answer for thoe who can't take the sun. They should consult their doctors first, though.


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