News Roche Turns to MS Research on Agreement with Versant Ventures Roche Turns to MS Research on Agreement with Versant Ventures by Patricia Silva, PhD | June 25, 2014 Share this article: Share article via email Copy article link The Swiss pharmaceutical companyĀ RocheĀ recently announced a partnership agreement with California-based Inception Sciences and venture capital firm Versant Ventures. The three companies will work together to form a new company, Inception 5, which will be dedicated mostly to the development of therapies for multiple sclerosis. Inception 5’s research will focus onĀ multiple molecular targets for remyelination, the process of repairing neural insulation. The company will also work towards building a remyelination screening platform, which will be led by investigators from the University of California. Myelin is a compound present in the neural sheaths which the immune system incorrectly identifies as a pathogen. Lesions on the myelin layer lead to aĀ wide and unpredictable range of neurological symptoms. However, the screening platform will enable clinicians to test how thousands of drugs spur oligodendrocytes to produce myelin. Versant Ventures, aĀ venture capital firm specializing in investments in game-changing biopharmaceutical and medical device opportunities, will provide the funding for the company, although the amount hasn’t been revealed. Roche, on the other hand, will finance the research based on a series of milestones. This agreement is part of Roche’s efforts to diversify its offer and research field beyond its expertise in cancer. The Basel-based firm had already begun other research projects for Alzheimer’s disease and schizophrenia, as well as other neurodegenerative disorders. [adrotate group=”4″] Roche will have the option of buying the partnership by the time the company delivers its first Investigational New Drug (IND) files, which involves a drug developer asking permission to the U.S. Food and Drug Administration to start testing the drug on humans. The name Inception 5 comes from Inception Science, which is a “small molecule pharmaceutical incubator” that was founded in 2011,Ā according to its website.Ā Versant Ventures uses the company to fund Inception spin-offs in collaboration with outside drug companies and the name Inception 5 suggest there were four prior. Print This Page About the Author Patricia Silva, PhD PatrĆcia holds a PhD in medical microbiology and infectious diseases from the Leiden University Medical Center, Netherlands, and completed a postdoctoral research fellowship at the Instituto de Medicina Molecular, Lisbon, Portugal. Her work in academia was mainly focused on molecular biology and the genetic traits of infectious agents such as viruses and parasites. PatrĆcia earned several travel awards to present her work at international scientific meetings. She is a published author of several peer-reviewed science articles. Tags myelin, remyelination, Roche
March 29, 2024 News by Margarida Maia, PhD Low estradiol hormone levels tied to worse brain damage in menopause