News New Multiple Sclerosis Society Funded Study Tests Whether Vibrating Insoles Improve Balance New Multiple Sclerosis Society Funded Study Tests Whether Vibrating Insoles Improve Balance by Patricia Inacio, PhD | December 16, 2014 Share this article: Share article via email Copy article link A new Multiple SclerosisĀ pilot studyĀ was awarded a $39,000 grant by the National Multiple Sclerosis Society to investigate how patients’ sensation in their feet while standing impacts balance and whetherĀ their ability to walk is improved through the use of vibrating insoles. Multiple Sclerosis is characterized by the destruction of the inner layer of nerve cells, mainly composed of myelin. This destruction is thought to occur either by patientsā own immune systems attacking the central nervous system, specifically myelin, or by cells failing to produce this component. Currently without any cure, MS affects over 2.3 million people throughout the world, leading to a diverse symptomatic disease, impacting visual, sensory, and motor capabilities. Ā As a consequence, MS patients exhibit major limitations, notably fatigue and balance impairments. In this study, a team of researchers at the University of Massachusetts AmherstĀ will evaluate the sensation in patientsā feet soles (analyzing two different areas) and compare their results with healthy subjects. The analysis will be performed while sitting and standing up to determine how this impacts patients’ balance. The project introduces a new focus, since the majority of previous reports only determine patientsā parameters while lying down. Introducing a new standing parameter will allow determining how weight bearing impacts MS patients’ balance. The authors are recruiting both patients with Multiple Sclerosis and healthy subjects aged between 21 and 65 years old. Notably, all the participants have to be able to walk and stand up without assistance. Participantsā ability to be enrolled in the study will be determine by different tests including, muscle strength and the 25-foot walk; additionally, patients will be analyzed for skin sensation (pressure and vibration), standing balance and posture evaluation. [adrotate group=”4″] With all parameters evaluated, the project will determine the effect of a vibrant sole to be administered in patientsā feet while vibrating at low, undetectable frequencies. This will be achieved by small devices ā “factors” ā introduced in patients’ shoe soles in the areas previously assessed as the most sensitive. Patients will then be evaluated in a blind test, consisting of five different postures in five-minute intervalsĀ before repetition, during which patients will not know whether the “factors” are being used. In a final phase of the study, these results will allow the researchers to test how these factors help Multiple Sclerosis patients in the presence of an unexpected balance challenge, such as standing on a platform that without notice moves 3 inches (8 cm). The researchers highlight that the study will uncover the potential use of vibrating shoe soles in patients with balance impairments. Stephanie Jones in the department of kinesiology at UMass Amherst commented, “There is a lot of evidence that the somatosensory system, that is the skin’s sensation and body awareness or proprioception, is affected in people with MS, who often report peripheral sensory loss, for example. This method exploits the phenomenon of stochastic resonance of the nervous system. It applies a kind of ‘noise’ that can enhance a person’s skin sensation. If we identify this mechanism of somatosensory impairment in MS, perhaps we can develop other interventions to try to do more.” Print This Page About the Author Patricia Inacio, PhD Patricia holds her PhD in cell biology from the University Nova de Lisboa, Portugal, and has served as an author on several research projects and fellowships, as well as major grant applications for European agencies. She also served as a PhD student research assistant in the Department of Microbiology & Immunology, Columbia University, New York, for which she was awarded a Luso-American Development Foundation (FLAD) fellowship. Tags National Multiple Sclerosis Society
April 23, 2024 News by Margarida Maia, PhD AAN 2024: Subcutaneous Ocrevus led to nearly no relapses after year
April 22, 2024 News by Margarida Maia, PhD Viatris launches low-dose Copaxone generic formulation in Canada
April 22, 2024 News by Marisa Wexler, MS AAN 2024: Briumvi found to ease disability in certain MS patients