Inflammatory lesions within the brain, called paramagnetic rim lesions, visible on imaging scans may improve the accuracy of a multiple sclerosis (MS) diagnosis, especially when used in combination with other imaging-based biomarkers, a study reported.
If corroborated in larger future studies, these white matter lesions may serve as an early diagnostic biomarker.
The study, “Paramagnetic Rim Lesions Are Specific To Multiple Sclerosis: An International Multicenter 3T MRI Study,” was published in the journal Annals of Neurology.
Accurate and early diagnosis is critical in MS, where certain treatments can offer profound health benefits. But misdiagnoses can run as high as 20%, according to some estimates.
Two potential biomarkers that can be measured non-invasively by MRI are brain lesions caused by inflammation, called central vein sign (CVS) and paramagnetic rim lesions (PRL).
An international team of researchers reviewed MRI records covering 329 people with MS and 83 people with non-MS neuroinflammation, looking for how frequently PRL occurred between the two.
We are sorry that this post was not useful for you!
Let us improve this post!
Tell us how we can improve this post?