March 22, 2024 News by Marisa Wexler, MS MS lesions grow from center outward, new mapping study shows In multiple sclerosis (MS), lesions ā areas of abnormal tissue in the nervous system ā start as a core of a few inflammatory immune cells, with inflammatory damage then spreading outward from these cells to form a lesion. That’s according to a new study from Sweden, in which researchers…
March 12, 2024 News by Marisa Wexler, MS MS lesions may start as small clumps of microglia in patient’s brain In multiple sclerosis (MS), lesions in the brain may start with small clusters of immune cells called microglia, a new study reveals. Scientists are working to understand exactly how these small clusters may develop into MS lesions, which they hope could uncover new targets for treating the disease.
November 27, 2023 News by Marisa Wexler, MS FDA clears AI tool for detecting disease activity on MRI scans Pixyl.Neuro, a next-generation software that uses artificial intelligence (AI) in analyzing MRI scans to help detect and monitor multiple sclerosis (MS) disease activity, has received 510(k) clearance from the U.S. Food and Drug Administration (FDA) for clinical use. 510(k) clearance is required for medical devices used in the…
August 29, 2023 News by Marisa Wexler, MS Memory problems in MS tied to lesions in brain’s ‘memory circuit’ The presence of lesions, or regions of damage, in a brain circuit tied to memory in stroke patients also associate with memory problems in multiple sclerosis (MS), a study shows. Findings may help to determine which lesions are likely to cause memory issues in people with the neurodegenerative condition,…
November 10, 2022 News by Marisa Wexler, MS Measuring Growth of Lesions in MS Better Predicts Disability Progression Measuring how lesions get bigger over time in multiple sclerosis (MS) can predict long-term disability progression more accurately than other lesion-based assessments, a new study reports. “Enlargement of T2 [total] lesions, and specifically of its volume, … is more strongly associated with long-term disability progression compared to other…
May 26, 2022 News by Marisa Wexler, MS Lesions in 3 Brain Regions Can Help Distinguish MS From Like Disorders People with multiple sclerosis (MS) are more likely to have lesions in three regions of the brain ā the anterior temporal horn, periventricular region, and cerebellar hemisphere ā compared with people with other inflammatory brain diseases, a study reports. Looking for lesions in these parts of the brain may…
September 26, 2019 Columns by Tamara Sellman Need to Know: What Is an MS Mimic? Editor’s note: “Need to Knowā is a series inspired by common forum questions and comments from readers. Have a comment or question about MS? Visit our forum. This week’s question is inspired by the forum topicĀ “Is it an MS Diagnosis or is it something else? ” from July…
September 14, 2018 News by Ana Pena PhD Phagocytes, Key Immune Cells, Seen to Switch from Promoting to Repairing MS Lesions in Study Phagocytes, diverse cells of the innate immune system, are known to bothĀ promote and prevent inflammation, depending on whether they are programed to damage tissue or to repair it. A study in mouse model of multiple sclerosis (MS)Ā now reports that this programming is not fixed, and that pro-inflammatory…
March 26, 2018 Columns by Debi Wilson My Unique Primary Progressive MS Diagnosis I have lived with the diagnosis of primary progressive multiple sclerosis (PPMS)Ā for almost eight years. For many years prior to that diagnosis, I was confused by what could be causing my abnormal gait, extreme fatigue, blurred vision,Ā and trouble concentrating. During that time, I completed many diagnostic tests, dealt…
April 21, 2016 News by Margarida Azevedo, MSc Mayo Clinic Neurologist, Creator of MS Lesion Tissue Bank, Receives 2016 John Dystel Prize for MS Research Dr. Claudia Lucchinetti, chair of the Department of Neurology at the Mayo Clinic and the Eugene and Marcia Applebaum Professor of Neurosciences, hasĀ received the 2016 John Dystel Prize for Multiple Sclerosis Research, an honor jointly awarded by the National Multiple Sclerosis Society and the American Academy of Neurology…
February 10, 2016 News by Patricia Silva, PhD MS Study Finds Lipid Antibodies Reflect Changes in Brain Volume and Lesions Brigham and Womenās HospitalĀ researchers reported that antibodies directed at lipids are associated with magnetic resonance imaging (MRI) measures of brain degenerationĀ in patients with multiple sclerosis (MS), and may potentially serve asĀ biomarkers for monitoring disease status. While the hyperintense brain lesions detected by MRI are crucial for diagnosis and therapeutic…
December 10, 2015 News by Patricia Inacio, PhD Potential MS Biomarker Seen in Adipose Tissue Secretion In a new study titled āAdipsin Is Associated with Multiple Sclerosis: A Follow-Up Study of Adipokines,ā researchers report a correlation between an adipokine called adipsin and the pathogenesis of multiple sclerosis (MS). The study was published in the Multiple Sclerosis International journal. Obese adolescents…