gene expression

Interferon beta corrects gene processing disrupted in MS: Study

Alternative splicing, a biological process that allows a single gene to code for multiple proteins, is extensively disrupted in immune cells isolated from untreated multiple sclerosis (MS) patients, and long-term treatment with interferon beta-based therapies largely corrects the defects, a study found. ā€œAlternative splicing is a potential biomarker warning…

Some RRMS and SPMS Patients Share a Similar Gene Expression in Response to IFN Treatment

In a new study entitled ā€œTranscriptional response to interferon beta-1a treatment in patients with secondary progressive multiple sclerosis,ā€ a team of researchers discovered a subgroup of secondary progressive multiple sclerosis patients (SPMS) exhibiting the same gene expression response to interferon (IFN) treatment as patients with relapsing-remitting MS…