microRNAs

Loss of Specific microRNA Seen to Lessen Disease Severity and Myelin Loss in MS Mouse Model

Removing a specific microRNA molecule ā€” miR-150 ā€“ eased disease severity, inflammation, and loss of myelin in a mouse model of multiple sclerosis (MS), researchers report. Their study, ā€œSilencing miR-150 Ameliorates Experimental Autoimmune Encephalomyelitis,ā€ was published in the journal Frontiers in Neuroscience. Micro RNAs (miRNAs) are…

MS Susceptibility May be Influenced by Female-Specific Variations in MicroRNAs-Coding Genes

In a new study entitled ā€œVariants of MicroRNA Genes: Gender-Specific Associations with Multiple Sclerosis Risk and Severity,ā€ researchersĀ identified variations in genes coding for microRNAs that influence patients’ susceptibility to develop multiple sclerosis, as well as the disease course. Most importantly, these variations were gender specific, identified only…