symptoms

A research team recently showed that key enzymes of energy metabolism pathways are differentially expressed in active and inactive multiple sclerosis (MS) lesions, and may contribute to axonal degeneration in MS. The study, titled “Differential expression of glucose-metabolizing enzymes in multiple sclerosis lesions,” was published in the…

In a new study, researchers from the University of Toronto, Canada, uncovered the process behind the formation and maintenance of tertiary lymphoid tissues (TLTs), structures found in the meninges in the brains of multiple sclerosis (MS) patients. Their findings, reported in the article “Integration of Th17- and Lymphotoxin-Derived Signals Initiates…

In a new study titled “Adipsin Is Associated with Multiple Sclerosis: A Follow-Up Study of Adipokines,” researchers report a correlation between an adipokine called adipsin and the pathogenesis of multiple sclerosis (MS). The study was published in the Multiple Sclerosis International journal. Obese adolescents…

The Multiple Sclerosis Society (MS Society) in the U.K. recently announced  awards targeted towards new MS research. In total, 16 projects carefully selected by both a panel of experts and patients living with MS will share MS Society 2015 funding grants amounting to £1,979,879. All projects fulfilled the requirements of high scientific…

Several studies have shown that exercise can improve movement in multiple sclerosis (MS), but new research indicates that it specifically may also  improve reaction time, a measurement of cognitive impairment. The study, titled “Acute effects of varying intensities of treadmill walking exercise on inhibitory control in persons with…

A smartphone platform may eventually enable large-scale studies of patients with multiple sclerosis (MS) or other neurologic diseases, according to the findings of a recent study published in the journal Neurology, Neuroimmunology & Neuroinflammation. Smartphones, highly portable and popular, provide a significant opportunity to incorporate information across…

In a new study entitled “Transcription factor Nr4a1 couples sympathetic and inflammatory cues in CNS-recruited macrophages to limit neuroinflammation,” a team of scientists discovered the mechanism by which autoreactive T cells are capable of penetrating a patient’s brain and induce multiple sclerosis. The study was recently published in the advance online issue…

Barcelona, Spain-based, global pharma firm Almirall presented new clinical evidence at the 31st Congress of the European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS) — held in Barcelona October 7–10, 2015 — supporting the efficacy of its Sativex product, currently the only pharmaceutical medicine derived from cannabinoids…

Results from a recent study published in the journal Immunity indicate that dietary fat has an influence in the duration and severity of autoimmune flare-ups in a mouse model of multiple sclerosis. The team of researchers also showed that adjusting the length of the fatty acids consumed by…

Flex Pharma, Inc., a biotechnology company focused on therapies for muscle cramps and spasms associated with neuromuscular conditions, recently announced that it will present new data on its therapeutic agent FLX-787 at the 2015 Annual Meeting of the Society for Neuroscience, currently taking place in Chicago (October 17–21).

In a recent study published in the International Journal of MS Care, a team of researchers determined that among patients with multiple sclerosis (MS), fatigue was the most common symptom associated with the decision to leave work or reduce the employment status. According to the researchers, comprehensive…

A recently published study in the journal PLOS One reported a new tool to assess risk knowledge in multiple sclerosis (MS) patients. The study was conducted by an international team led by researchers at the University Medical Center Eppendorf in Hamburg, Germany, and is entitled “…

Adamas Pharmaceuticals, Inc., a pharmaceutical company focused on chronic conditions that affect the central nervous system, recently announced results from two non-clinical studies showing that the company’s product candidate ADS-5102 can be potentially applied as a treatment for multiple sclerosis (MS) symptoms. MS is a chronic, progressive neurodegenerative autoimmune…

Genzyme recently announced a novel worldwide initiative called vs.MS, whose goal is to increase awareness of the psychical and emotional toll of relapsing multiple sclerosis (RMS) on patients and their caregivers. To enhance the comprehension of the full burden of RMS, Genzyme conducted a large-scale survey of more than 1,500 individuals…

An international research team recently reported that the web-based MSdialog app is being adopted by both multiple sclerosis (MS) patients and healthcare providers. The study is entitled “Patient and Physician Perspectives on MSdialog, an Electronic PRO Diary in Multiple Sclerosis” and was published in the journal…

A new study recently published in the journal PLOS One revealed that multiple sclerosis (MS) patients have a microbial imbalance (dysbiosis) in their gut microbiota that is most likely linked to the disease pathogenesis. The study is entitled “Dysbiosis in the Gut Microbiota of…

Melatonin, the same hormone that helps people fall asleep by regulating the body’s internal clock, may be helpful in treating multiple sclerosis, according to a study from Raúl Carrea Institute for Neurological Research in Buenos Aires. Neurologists Dr. Mauricio Farez and Dr. Francisco Quintana noticed that when melatonin levels are…

A new study entitled “Effect of Smoking Cessation on Multiple Sclerosis Prognosis” recently revealed that smoking by patients with multiple sclerosis (MS) post diagnosis accelerates their disease progression course. The study was published in the journal JAMA Neurology and was led by researchers at the…

In a new study entitled “Neutrophil trails guide influenza-specific CD8+ T cells in the airways,” researchers uncovered a key mechanism mediated by neutrophils that guides immune system cells to the site of an injury or infection. Moreover, this mechanism is crucial for immune cells to function properly…

Researchers at the University of Athens Medical School in Greece have found that people with early stage multiple sclerosis (MS) and overactive bladder (OAB) have reductions in brain serotonin and a stress-related hormone, cortisol. Serotonin is a chemical that helps nerve cells to communicate. The study, titled “Neurochemical and…

In a recent study published in the Journal of Neuroimaging, a team of researchers from the UCLA have reported the first evidence that obstructive sleep apnea contributes to a breakdown of the blood–brain barrier, which plays an important role in protecting brain tissue. The findings are significant for…

In a new review entitled “Fatigue in multiple sclerosis: a look at the role of poor sleep” author Lauren Strober, PhD explores the link between secondary fatigue and sleep disturbance in multiple sclerosis patients. The study was published in the journal Frontiers in Neurology.

Multiple sclerosis patients prescribed Gilenya (fingolimod) are now being informed about a handful of documented cases where the therapy was found to have led to a rare brain infection, according to the US Food and Drug Administration. The FDA has released a public warning indicating that cases of progressive multifocal leukoencephalopathy (PML) have been…

The major challenge patients with multiple sclerosis face is nearly constant muscle weakness and fatigue caused by progressive nerve and neurological damage. It is well established that these symptoms dramatically affect quality of life in MS patients, making it more difficult to work, partake in hobbies, and enjoy family and social interactions.

The ability to assess risk may decline as multiple sclerosis disease status progresses over time, as determined by a recent study from University of Alberta in Canada. Principal investigator Esther Fujiwara, PhD, and lead author of the study, Ashley Radomski, used the game of dice task (GDT) to challenge patients…

A new study led by researchers at the Center for BrainHealth at the University of Texas at Dallas and The University of Texas Southwestern Medical Center recently revealed that multiple sclerosis (MS) patients experience cognitive deficits due to a decreased connectivity between functional networks in the brain. The…

In a recent study published in the journal Nature Communications, LMU clinicians have clarified the lifespan of antibody-producing cells and have also identified a novel biomarker that could be used to monitor autoimmune conditions such as multiple sclerosis and lupus erythematous. The humoral immune response is mediated by cells…

With 26 states plus the District of Columbia now allowing medical marijuana use, according to a recent North American Research Committee on Multiple Sclerosis (NARCOMS) survey, many people with multiple sclerosis are considering the herb as a therapeutic option. NARCOMS is a research program that allows people with Multiple Sclerosis…

In a recent review published in the journal Seminars in Arthritis and Rheumatism, German researchers explored the complexity of interwoven pathways of osteopenia, and how it relates to diseases such as MS. Osteopenia is a bone condition characterized by a decreased density of bone, which leads to bone…

Researchers in the Department of Immunology at St. Jude Children’s Research Hospital in Memphis were able to identify a faulty “brake” in immune cells which may be involved in the inflammation triggering multiple sclerosis (MS). This brake is believed to be able to control inflammation, offering the potential for the development of new…