symptoms

As we age, the risk that small blood vessels will start leaking into brain tissue increases, raising our risk of dementia, stroke, and Parkinson’s disease. New research reveals that people with multiple sclerosis (MS) also have these so-called cerebral microbleeds, and links them to increased physical and cognitive disability. When Robert Zivadinov, a professor of…

Flex Pharma, Inc., announced the start of a Phase 2 clinical trial assessing the safety and efficacy of FLX-787 in multiple sclerosis (MS) patients who suffer from cramps, spasms, and/or spasticity as a result of the disease. The trial is being run in conjunction with Neuroscience Trials Australia. Flex Pharma’s FLX-787 is a single molecule,…

Optic neuritis is one of the symptoms of which those of us who live with multiple sclerosis on a daily basis know can set us apart from others. We are fully, and often painfully, aware that everyone is different. We all experience a different array of symptoms to similarly different…

Novel molecular imaging compounds that detect neuroinflammation in the brain of multiple sclerosis (MS) patients have been developed by researchers at the Washington University School of Medicine in Missouri, and may help to uncover the triggers of such inflammation and to better evaluate new disease treatments. The study, “Development and…

One June 3, a workshop titled “Metabolism in MS and Related Conditions” was presented at the 2016 Annual Meeting of the Consortium of Multiple Sclerosis Centers (CMSC), held June 1-4 in National Harbor, Maryland. One of the speakers was Dr. David Sheikh-Hamad, professor of medicine-nephrology at Baylor College of…

Researchers at Texas Woman’s University identified tai chi as a beneficial therapy for multiple sclerosis (MS) patients with impaired balance, as it can improve their endurance and strength and decrease fatigue. The results of the study, “The Benefit of Tai Chi for Balance and Gait in People with…

Researchers from Mount Sinai Rehabilitation Hospital found that patients with multiple sclerosis (MS) who complain of speech limitations or difficulty in swallowing cannot produce specific phonemes, which may be a helpful way of objectively quantifying these symptoms in MS patients. The findings were recently reported in an oral presentation titled “Rate of…

Most research in multiple sclerosis (MS) has focused on the impact of the disease on the lower extremities. To balance this, researchers at Mount Sinai Rehabilitation Hospital in Connecticut thoroughly characterized upper arm and hand functions in MS patients, finding that disease duration and disability level differently affected various…

Mayis Al Dughmi, of the Physical Therapy and Rehabilitation Science at the University of Kansas Medical Center, recently presented her findings on the relationship between fatigue, measured using the Neurological Fatigue Index (NFI-MS), and sleep quality and attentiveness in patients with multiple sclerosis (MS). The findings indicate that cognitive…

Multiple sclerosis (MS) patients using an interactive, self-guided fatigue management resource, developed by researchers from the University of Alberta in Canada, reported lower fatigue and improved cognition after three months, showing that fatigue self-management tools can contribute to the treatment of this common MS symptom. The pilot study, “…

Sexual dysfunction correlates with depression and bladder dysfunction in Hispanic patients with multiple sclerosis (MS), according to the results of a recent study presented at the 2016 Annual Meeting of the Consortium of Multiple Sclerosis Centers (CMSC). The study, “Sexual Dysfunction and Its Correlation to Depression and Bladder Dysfunction in…

Identifying multiple sclerosis (MS) patients who suffer from dysphagia — swallowing difficulties — early on allows the prevention of aspiration pneumonia, a leading cause of death in MS. Researchers at Baylor College of Medicine in Texas developed a screening tool to detect dysphagia and presented encouraging preliminary data on…

Poor sleep quality may be associated with impaired memory and decreased functional abilities in multiple sclerosis (MS) patients, according to the study “Impact of Sleep Quality on Cognitive and Physical Function in Individuals with Multiple Sclerosis.” The study was presented during the Whitaker Research Track Session II at the…

By the time I went through various tests that led to being diagnosed with multiple sclerosis 14 years ago, epilepsy had already been part of my life since the age of 19. No one mentioned any link. The neurologist’s words still ring in my ears. Having already told me that MS was the diagnosis,…

There has been a great deal of talk and conjecture about the relationship between multiple sclerosis (MS) and vitamin D, often linked to living in an area lacking sunshine. Indeed, when I lived in the United Kingdom, which is notorious — or should be — for seemingly endless gray skies and…

I’m sure I’m not alone when I say that I’m glad to be done with cold and dreary weather. Bring on the sunshine! But my excitement is tempered a bit because, like many people with MS, I find the heat exhausting; it saps my energy and makes it even harder…

A bicycle specially designed to mimic the symptoms of multiple sclerosis (MS) now has its own owner’s manual, and the group behind the bike’s creation is inviting anyone interested to build their own experience of the spasticity and physical discomforts so well-known to people with the disease. The manual, which…

Children and adolescents with multiple sclerosis (MS) differ from others in the composition of their gut flora, with higher levels of inflammation-causing bacteria and lower levels of anti-inflammatory bacteria, according to a study from  the University of British Columbia, Canada. The findings, supporting previous hypotheses that the composition of the gut microbial community could influence the development…

A new study suggests a strong association in multiple sclerosis (MS) patients between high levels of fatigue and mental health, quality of life (QoL), and the ability to move about and participate in daily activities, although disability is not related to fatigue levels.  These findings are of importance and highlight the…

Rebound symptoms after stopping fingolimod (Gilenya) treatment affect a “clinically relevant” number of multiple sclerosis (MS) patients, a study by University of California, San Francisco, researchers reported. The study called attention to the need for determining the best method of sequencing or stopping MS treatments, and highlighted the need to identify factors…

Exercises like yoga and aquatic programs can help ease some symptoms of multiple sclerosis (MS), especially fatigue, depression and paresthesia, researchers report in a study published in the journal Medicine & Science in Sports & Exercise, and titled “Exercising Impacts on Fatigue, Depression, and Paresthesia in Female Patients with Multiple…

Researchers at Purdue University have developed a method of identifying subtle oscillations in a person’s posture that mirror an excessive delay in neuromuscular responses, indicating a neurologic deficit. The oscillations, which differ from the normal tendency of a standing person to sway, may aid in diagnosing neuromuscular disorders such as multiple sclerosis (MS).

In a study published in the International Neurology Journal, researchers showed that cognitive deficits, such as memory problems, in a rat model of multiple sclerosis (MS) are mirrored by changes in synaptic transmission and plasticity in the hippocampus, a brain region crucial for memory processing. The findings…

Researchers at the School of Medicine of the University of California (UC), Riverside, found that TNF-alpha, a factor known for its pro-inflammatory actions, also triggers processes that end inflammation by inducing a type of immune surveillance cell, called M-cells. By advancing our understanding of immune processes, the finding may lead to…

The Consortium of Multiple Sclerosis Centers (CMSC) 2016 Annual Meeting will open with the John F. Kurtzke Memorial Lecture, “Do Relapses Really Matter?”, by the renowned multiple sclerosis (MS) expert Dr. Fred D. Lublin of Mount Sinai Medical Center. The June 1 lecture offers a fresh view on recent evidence into the impact…

Urinary tract symptoms affect a large proportion of patients with multiple sclerosis (MS), yet their extent and type is not well-known. A study reported that among a cohort of people with the disease, almost 70 percent had urinary tract problems, adding to the extent of their disability. The study,…

Researchers reported that patients with myelitis who later develop multiple sclerosis (MS) might be distinguished from others with myelitis by a number of characteristics, like the location and size of spinal cord lesions, a finding that might help clinicians diagnose MS and initiate treatment at an early stage. Myelitis, an…

Scientists at the Pediatric MS Center at NYU Langone, New York, reported that U.S. adolescents with multiple sclerosis (MS) receiving interferon-beta 1a therapy had a higher body mass index (BMI), more relapses, and were managed differently compared to patients of similar age in seven other countries. The study, “Subcutaneous…

New research from Argentina explores the idea that controlling symptoms of type 2 diabetes (metabolic syndrome) can also beneficially impact multiple sclerosis (MS) disease progression. The study,“Immunologic Effects of Metformin and Pioglitazone Treatment on Metabolic Syndrome and Multiple Sclerosis,“ appeared March 7 in the journal…

Damage to the cerebellum in people with multiple sclerosis (MS) is due more to the death of actual nerve cells than the destruction of white matter connections, a new study out of Italy suggests. The article, which challenges previous ideas about how brain damage in MS occurs, is titled “MRI-detectable cortical lesions in the…