Posts by: Alice Melão

Alice Melão

June 13, 2019June 13, 2019

DELIVER-MS Trial Recruiting RRMS Patients to Help Improve Treatment Decision-making

News

A clinical trial based at the Cleveland Clinic and the University of Nottingham, U.K., is recruiting patients with relapsing-remitting multiple sclerosis (RRMS) to compare two treatment strategies, the National ... Read more

April 30, 2019April 30, 2019

Stem Cells in Mouse Hair Seen to Aid Growth of ‘Dense’ Myelin Sheaths Around Nerve Cells, Study Reports

News

A subset of stem cells in hair follicles, called melanocytes, appear to do more than just give rise to mature melanocytes, cells that help to determine hair color. Those ... Read more

April 26, 2019April 30, 2019

Active Form of Vitamin D Can Regulate Immune Responses in Diseases, Including MS, Study Shows

News

An active form of vitamin D can modulate the activity of immune cells and prevent autoimmune reactions known to be involved in several human diseases such as multiple sclerosis ... Read more

April 16, 2019April 16, 2019

Life Partners of RRMS Patients Experience High Strain Even in Early Disease Stages, Study Finds

News

Cognitive and neuropsychiatric problems caused by relapsing-remitting multiple sclerosis (RRMS) — such as memory and processing issues, depression, and irritability — are the main source of strain among life ... Read more

April 2, 2019April 2, 2019

Analysis of TWEAK Protein Levels May Help Identify Active Inflammation in MS Patients, Study Suggests

News

High blood levels of a signaling protein known as TWEAK are associated with active neuroinflammation in patients with multiple sclerosis (MS), a study shows. This finding suggests that TWEAK ... Read more

March 27, 2019March 27, 2019

$1.5 Million Earmarked to Attract Neurologists, Improve Speciality Care in El Paso County

News

Texas Tech University Health Sciences Center (TTUHSC) El Paso has received a $750,000 gift to establish an endowed chair in the department of neurology. TTUHSC will match that donation to provide ... Read more

February 28, 2019February 28, 2019

National MS Society Grants $50,000 to Kessler Researchers to Study Processing Speed in MS

News

Kessler Foundation researchers Ekaterina Dobryakova, PhD, and Pei-Pei Liu, PhD, have been awarded a $50,000 grant by the National Multiple Sclerosis (MS) Society to study the speed at which MS ... Read more

February 27, 2019March 7, 2019

FDA Will Review New Drug Application of Diroximel Fumarate for Relapsing Forms of MS

News

The U.S. Food and Drug Administration (FDA) has agreed to review Alkermes’ request to approve diroximel fumarate (BIIB098) as a treatment for relapsing forms of multiple sclerosis (MS), the ... Read more

February 12, 2019February 12, 2019

Direct Nerve Stimulation Using MyoRegulator System Seen to Reduce Spasticity in Mice with Spinal Injury

News

Treatment with PathMaker Neurosystems’ anodal trans‐spinal direct current stimulation (tsDCS), a non-invasive direct nerve stimulation tool called MyoRegulator, was found to effectively ease spasticity in mice with spinal cord injury, a ... Read more

February 1, 2019February 7, 2019

Study Shows Benefits of Low Temperature Exercise for MS Patients

News

Reducing body temperature during physical exercise can help rewire the brain and improve motor control in patients with multiple sclerosis (MS), a new research study at Canada’s Memorial University shows. ... Read more

January 31, 2019January 31, 2019

MS Patients Sought to Test Alternative Chronic Pain Treatment Methods

News

A clinical trial funded by the National Multiple Sclerosis Society is recruiting adult patients with multiple sclerosis (MS) to test two non-pharmacological strategies to manage MS-related chronic pain. The ... Read more

January 21, 2019January 28, 2019

Herbicide Called Linuron Seen to Trigger Inflammatory Signals Linked to MS in Study

News

The herbicide linuron, commonly used with other herbicides, insecticides and fungicides to control the growth of grass and weeds, may be an important environmental risk factor in the development ... Read more

January 15, 2019March 11, 2019

UK Experts Propose New Guidelines to Treat Women with MS Before, During, After Pregnancy

Aubagio, News

Multiple sclerosis (MS) experts in the United Kingdom have proposed consensus guidelines for the management and treatment of pregnant women with the disease, and couples affected by MS who ... Read more

January 11, 2019January 11, 2019

WeHealth, PathMaker Collaborating to Develop MyoRegulator as Noninvasive Treatment for Spasticity

News

WeHealth by Servier and PathMaker Neurosystems have established a new partnership to develop and commercialize the first neuromodulation technology for noninvasive treatment of spasticity, the companies announced. The agreement establishes ... Read more

January 11, 2019January 14, 2019

Mavenclad Approved for Reimbursement as RRMS Treatment in Australia

News

Australia was one of the first countries to approve the use of Mavenclad (cladribine tablets, 10 mg) to treat patients with highly active relapsing-remitting multiple sclerosis (RRMS). Now, the country’s ... Read more

January 9, 2019January 9, 2019

Five Finalists Vie for $1 Million Prize in Mobility Unlimited Challenge

News

Five finalists remain in the running for the $1 million prize being offered in the Mobility Unlimited Challenge, a global competition to promote the development of innovative solutions for personal ... Read more

January 7, 2019January 7, 2019

More Effort Needed to Recruit Minorities to Phase 3 Clinical Trials, MS Expert Says

News

Because multiple sclerosis (MS) presentation and progression course can be very different between people of African ancestry and Caucasians, the recruitment of minorities to Phase 3 clinical trials is ... Read more

December 20, 2018December 20, 2018

Cannabis-based Sublingual Tablet to Enter Trials in Israel as Possible Spasticity Treatment, OWCP Says

News

OWC Pharmaceutical Research is planning new clinical studies to evaluate the activity and safety of its cannabinoid-enriched sublingual soluble tablet. The company announced that an Institutional Review Board (IRB) in ... Read more

December 18, 2018December 18, 2018

FDA Asked to Approve Diroximel Fumarate as Oral Treatment for Relapsing MS

News

Alkermes filed a request for the approval of diroximel fumarate (BIIB098) to treat relapsing forms of multiple sclerosis (MS) with the U.S. Food and Drug Administration (FDA). If approved, diroximel fumarate ... Read more

December 12, 2018December 12, 2018

Ocrevus Now Available Through NHS Scotland to Treat RRMS

News

Ocrevus (ocrelizumab, by Genentech) is now available through the National Health System (NHS) of Scotland to treat patients with relapsing-remitting multiple sclerosis (RRMS). The decision by the Scottish Medicines ... Read more

December 11, 2018December 11, 2018

WUSTL Team Receives $6.3 Million Grant to Develop PET Scan Tracers

News

The Washington University School of Medicine in St. Louis (WUSTL) will create a new research center to investigate and advance the development of tracers for positron emission tomography (PET) scans. ... Read more

November 30, 2018December 13, 2018

Gilenya Now Approved in Europe to Treat Children, Adolescents with RRMS

News

Gilenya (fingolimod) was approved by the European Commission as a treatment for children and adolescents, ages 10 to 17, with relapsing-remitting multiple sclerosis (RRMS), Novartis announced. The therapy is ... Read more

November 28, 2018December 4, 2018

Artificial Intelligence May Help Reduce Dosage of Gadolinium in MRIs, Researchers Suggest

News

Artificial intelligence can help reduce the amount of gadolinium used as a contrast agent in MRI (magnetic resonance imaging) scans, preventing the agent’s potential toxicity when accumulated in body ... Read more

November 21, 2018November 21, 2018

Phase 2 Trial of NurOwn Stem Cell Therapy in Progressive MS Planned for US, BrainStorm Announces

News

BrainStorm Cell Therapeutics is planning to launch a Phase 2 clinical trial in the United States to evaluate the safety and activity of its lead cell therapy candidate, NurOwn, in ... Read more

November 20, 2018March 20, 2019

FDA Approves Generic Version of Aubagio to Treat Relapsing MS, Glenmark Pharma Says

Aubagio, News

The U.S. Food and Drug Administration (FDA) has approved a generic version of  Aubagio (teriflunomide) tablets at the 7 mg and 14 mg  doses marketed by Sanofi, according to the ... Read more

November 1, 2018November 6, 2018

Protein Produced by Common Gut Bacteria Can Trigger Autoimmunity, Study Suggests

News

Bacteria that reside in human gut may trigger autoimmune reactions by producing human-like proteins that mimic a naturally occurring and crucial cell protein. Researchers at Queen’s University Belfast in ... Read more

October 29, 2018October 29, 2018

Mavenclad Named ‘Rapid Uptake Product’ in UK with Goal of Speeding Its Availability in NHS

News

Mavenclad (cladribine tablets, 10 mg) was one of the seven medicinal and medical technology products selected by the Accelerated Access Collaborative (AAC) as a “rapid uptake product” — a ... Read more

October 25, 2018October 31, 2018

Stem Cells from MS, Parkinson’s Patients Voyaging to Space Station to Study Disease Impact on Brain in Microgravity

News

Stem cells from patients with Parkinson’s disease and primary progressive multiple sclerosis (PPMS) are soon to voyage into space, and be brought aboard the International Space Station so cell-to-cell interactions in ... Read more

October 19, 2018October 23, 2018

Enzyme Produced by Gut Bacteria Linked to T-cell Attacks on Myelin in Study

News

An enzyme produced by bacteria in the gut was seen to activate immune cells linked to the development and progression of multiple sclerosis, a finding that may pave the way for ... Read more

October 18, 2018October 25, 2018

#ECTRIMS2018 – Role of Brain Atrophy in MS Progression Poorly Understood by Patients, MSAA Survey Finds

News

Although brain atrophy — the loss of brain volume — is an increasingly important measure in multiple sclerosis trials and treatment outcomes, MS patients have a limited understanding of ... Read more

October 15, 2018October 15, 2018

#ECTRIMS2018 – Additional Analysis on Ozanimod Demonstrate Its Potential to Treat Relapsing MS

News

Additional analysis of clinical data from Celgene’s investigational agent ozanimod continues to demonstrate its potential to benefit patients with relapsing multiple sclerosis (MS). Findings from the Phase 3 SUNBEAM ... Read more

October 12, 2018October 12, 2018

#ECTRIMS2018 – MS Patients More Prone to Health Problems Before, After Diagnosis, Study Suggests

News

Patients with multiple sclerosis (MS) are more likely to experience health problems before they receive their formal diagnosis, as well as to experience serious non-MS-related complications after diagnosis, a ... Read more

October 10, 2018October 10, 2018

#ECTRIMS2018 — Merck KGaA to Present Latest Data on MS Portfolio

News

Merck KGaA will present the latest advances made on several of its therapies aiming to treat multiple sclerosis (MS) at the 34th Congress of the European Committee for Treatment ... Read more

October 10, 2018October 17, 2018

FDA, EMA Agree to Review Novartis Therapy Siponimod to Treat SPMS

News

Novartis is seeking U.S. and European approval of its investigational oral agent siponimod to treat adults with secondary progressive multiple sclerosis (SPMS). The U.S. Food and Drug Administration (FDA) has ... Read more

October 8, 2018October 8, 2018

UVA Scientist Awarded $5.6M by NIH to Further Study Lymph System and Brain Connection

News

Jonathan Kipnis, the researcher who discovered that lymphatic vessels are important mediators of the underlying molecular mechanism of multiple sclerosis (MS), has received the prestigious Director’s Pioneer Award from ... Read more

September 26, 2018September 26, 2018

Nyrada Identifies Novel IRAK4 Inhibitors that May Prevent Neuroinflammation

News

Nyrada, a subsidiary company of Noxopharm, discovered a set of novel compounds that can cross the blood-brain barrier and blood-nerve barriers, and inhibit a master regulator of chronic inflammation ... Read more

September 21, 2018September 26, 2018

Ocrevus Climbing as First-line DMT for RRMS Among Neurologists Surveyed in Spherix Report

News

Eighteen months after its entrance into the U.S. market, Genentech’s Ocrevus (ocrelizumab) has become the monoclonal antibody of choice to treat patients with multiple sclerosis (MS), according to a survey ... Read more

September 5, 2018September 5, 2018

Mavenclad Approved to Treat Highly Active Relapsing MS Patients in Ireland

News

Adults in Ireland with highly active relapsing multiple sclerosis (MS) now can be treated with Mavenclad (cladribine tablets, 10 mg), the first short-course oral treatment approved for this disease. ... Read more

August 8, 2018August 8, 2018

Quanterix’s Simoa Assay May Make Neurofilament Light Chain Useful Blood Biomarker of MS and Its Likely Progression

News

Quanterix’s ultra-sensitive Simoa assay has the potential to open new uses for the brain biomarker known as neurofilament light chain, including the possibility to detect early evidence of neurological ... Read more

August 2, 2018August 7, 2018

Potential B-cell Targeting Oral MS Treatment, PRN2246, Shows Ability to Reach Brain in Phase 1 Study

News

Results from a first-in-human study assessing the safety and early activity of PRN2246 confirmed that the oral compound can reach into the brain and spinal cord. This finding adds new ... Read more