Childhood stressors linked to future symptoms of pain, fatigue in MS
Experiencing certain stressors during childhood may predict the future presence and severity of fatigue, pain, and psychiatric conditions associated with…
Articles by Lindsey Shapiro, PhD
Protein that helps immune cells infiltrate MS brain ID’d in mice
In a surprise discovery, researchers found that deleting a protein called integrin alpha-3 blocked harmful immune cells from accessing the…
ECTRIMS 2023: Declining risk of SPMS conversion seen in registry
The risk of converting to secondary-progressive multiple sclerosis (SPMS) has declined in recent years for patients who have an…
ECTRIMS 2023: Sick days in years before diagnosis suggest MS prodrome
Multiple sclerosis (MS) patients had significantly more sickness-related work absences in the years leading up to their disease onset…
ECTRIMS 2023: Tolebrutinib found to show benefits for up to 3 years
Treatment with tolebrutinib for up to nearly three years was tied to low relapse rates, stable disability, and few…
ECTRIMS 2023: Obesity tied to disability progression, declines
Obese people with multiple sclerosis (MS) had faster disability accumulation, greater cognitive declines, and worse quality of life in…
ECTRIMS 2023: Early high-efficacy DMTs may help slow MS disability
People with relapsing-remitting multiple sclerosis (RRMS) who had an early start on high-efficacy disease-modifying therapies (DMTs) experience slower…
Remote therapy program found to ease depression for MS patients
A cognitive behavioral therapy (CBT) program delivered virtually — using self-paced remote modules — significantly eased depressive symptoms and improved…
Stem cell therapy found safe, effective in RRMS study
Nearly three-quarters of people with relapsing-remitting multiple sclerosis (RRMS) showed no signs of disease activity five years after receiving…
US study tracks distance Medicare patients travel to see neurologist
Nearly 1 in 5 people on Medicare — a U.S. federal insurance program for people ages 65 and older —…
Kessler Foundation researchers to explore improving cognition in MS
Researchers at the Kessler Foundation have received $725,499 from the National Multiple Sclerosis Society to study how to…
Disability after RRMS diagnosis may predict transition to SPMS
Greater self-reported physical disability within the first years of being diagnosed with relapsing-remitting multiple sclerosis (MS) is associated with…
Anti-inflammatory diet, synbiotics ease progressive MS symptoms
An anti-inflammatory diet combined with synbiotic supplements eased fatigue, pain, sexual dysfunction, and bladder and bowel problems in people with…
In MS, energy management, high-intensity exercise may have benefit
An energy management education program combined with high-intensity exercise during a three-week inpatient rehabilitation program didn’t lead to quality of…
Neubie electrical stimulation device found to help in progressive MS
A course of neuromuscular electrical stimulation using Neufit‘s neuro-bio-electric stimulator — a device dubbed Neubie — alongside physical therapy…
Tyruko, first Tysabri biosimilar, cleared in US to treat relapsing MS
The U.S. Food and Drug Administration (FDA) has approved Tyruko (natalizumab-sztn) as the first biosimilar of Tysabri to…
New tyrosine kinase inhibitor shows potential in MS mouse model
ASH41020, an investigational therapy from Ashvattha Therapeutics, significantly reduced disease severity and exhibited immunomodulatory properties in a mouse model…
Brain stimulation may offer promise for spasticity in MS: Study
Noninvasive brain stimulation (NIBS) may offer promise for treating spasticity in multiple sclerosis (MS), but more work is…
Disability, older age at start of DMT linked to worse cognition in RMMS
Older age and greater physical disability when starting a disease-modifying therapy (DMT) were linked to worse cognitive function for…
Benefits of intranasal Nogo-A antibody observed in mouse model
Delivering an antibody against the Nogo-A protein to a specific region of the nose called the olfactory mucosa improved motor…
Engineered probiotic found to ease symptoms in mouse model of MS
A lab-engineered probiotic, composed of live bacteria that colonize the gut, was able to ease signs of disease in a…
New EBV-targeted vaccine induces durable immune response in mice
Researchers have developed a vaccine against the Epstein-Barr virus (EBV) — a leading environmental risk factor for multiple…
Physical activity may reduce fatigue in people with RRMS: Trial
More daily physical activity, better physical condition, and lower disability were all associated with less fatigue for people with…
Ibudilast treatment found to protect tissue integrity in brain in MS
Treatment with ibudilast — an anti-inflammatory being developed to treat people with progressive forms of multiple sclerosis (MS) —…
FDA decision on GA Depot for relapsing MS expected March 2024
The U.S. Food and Drug Administration (FDA) has agreed to review Viatris and Mapi Pharma‘s application seeking approval…
Three MS therapies listed as WHO essential medicines
For the first time, multiple sclerosis (MS) therapies have been added to the World Health Organization (WHO)’s Model…
Ekiva-MS app’s goal: Give patients stronger voice in care decisions
Dawn Health, a Danish digital health company, has developed a smartphone app to support and empower people living with…
Genetic risk found similar between RRMS, PPMS in Swedish study
The risk of developing multiple sclerosis (MS) was similar between first- and second-degree family members of people with…
Childhood diet can influence risk of MS and its clinical course: Study
What a person eats in childhood can influence their future risk of developing multiple sclerosis (MS) and its clinical…
Spinal cord lesions tied to higher risk of clinical relapse in MS: Study
The presence of spinal cord lesions — alone or with brain lesions — on MRI scans was associated with a…