MS patients may be at higher risk of stroke: Review study
The risk of having a stroke, that is, a blockage in blood flow to the brain that can cause lasting…
Articles by Margarida Maia, PhD
Immune signatures may predict MS course, treatment response
Researchers have identified three distinct immune signatures in the blood of people with early multiple sclerosis (MS)Â that seem to…
Nykode’s ‘inverse vaccine’ found to prevent MS in mouse model
An inverse vaccine developed by Nykode Therapeutics to boost immune system tolerance to a specific protein target was able…
Patients started early on Tysabri are less likely to relapse, study finds
People who start treatment with Tysabri (natalizumab) soon after being diagnosed with multiple sclerosis (MS) are at a…
Low estradiol hormone levels tied to worse brain damage in menopause
Low levels of the estrogen hormone estradiol may be linked to worse brain damage, a new study found, offering…
Vitamin D seen as most helpful for males in progressive MS rat model
Vitamin D supplements were associated with less severe disease in a rat model of progressive multiple sclerosis (MS), but…
Common MS therapies appear safe to use while breastfeeding
Taking antibody-based medications for multiple sclerosis (MS) while breastfeeding does not appear to harm a child’s health or development…
Comorbidities common in MS patients in clinical trials, study finds
Nearly half of all multiple sclerosis (MS) patients who participated in clinical trials — including global, pivotal studies —…
ACTRIMS 2024: Switch to Briumvi well tolerated in relapsing MS
People with relapsing forms of multiple sclerosis (MS) being treated with an infusion CD20 inhibitor such as Ocrevus…
ACTRIMS 2024: MRI Paramagnetic rim lesions tied to cognitive decline
The presence of paramagnetic rim lesions (PRLs), which represent areas of damage in the brain and spinal cord with chronic…
ACTRIMS 2024: An antihistamine may speed MS disease progression
The antihistamine clemastine accelerated disease progression by more than five times in some adults with progressive multiple sclerosis (MS)…
ACTRIMS 2024: Tolebrutinib fails to eliminate iron rim lesions in Phase 2 trial
Nearly one year of treatment with tolebrutinib, an oral small molecule being developed by Sanofi, failed to…
Australian researchers win grants to study immune system’s role in MS
Two researchers from The University of Western Australia (UWA) have received grants from MS Australia for work that may…
Balance training helps both in easing fatigue, restoring balance: Small trial
Both balance and endurance training can help to ease fatigue in people with multiple sclerosis (MS) — but if…
Stem cell therapy for MS seen to lower mitochondrial DNA in study
People with multiple sclerosis (MS) have higher amounts of mitochondrial DNA in their spinal fluid, which surrounds the brain…
Black MS patients in US score poorly on walking, physical ability tests
Black people with multiple sclerosis (MS) scored lower on tests of walking and physical function than did white patients,…
Most MS patients stay relapse-free 6 years after stem cell transplant
About 4 in 5 people with relapsing-remitting multiple sclerosis (RRMS) who receive a stem cell transplant remain free…
Complement protein activation is linked to more severe MS
Complement proteins, especially when activated in the brain and spinal cord, may contribute to nerve cell damage and more severe…
Melatonin at night may help with morning balance, strength in MS
Taking melatonin before bedtime may help balance and muscle strength in people living with multiple sclerosis (MS), according to…
Nabiximols, cannabis-based spray, eases spasticity in real-world use
Nabiximols, a cannabis-based oral spray sold as Sativex, was reported to considerably ease spasticity — unusual muscle tightness…
Caffeine tablets may help MS patients’ balance, mobility
Taking caffeine tablets — the equivalent to about two cups of coffee a day — may help people…
Crocin supplement seen to reduce signs of inflammation in MS
Taking a two-month supplement of crocin, an antioxidant found in the cooking spice saffron, helped to reduce signs of inflammation…
Pelvic floor exercises can help make sex more enjoyable, study finds
Pelvic floor exercises, which strengthen the muscles around the bladder, bowel, and vagina, can help with sexual health and lessen…
Cell-based therapy can be produced in under 3 days from blood sample
Kyverna Therapeutics has developed a method that enables KYV-101, an experimental CAR T-cell therapy for…
High-dose vitamin D does not slow MS lesion development
Taking a high-dose vitamin D supplement as an add-on to standard treatment for multiple sclerosis (MS)…
Head injuries, genetic makeup increase MS risk by up to 18 times
People with a certain type of genetic makeup who’ve have head trauma may have a risk of developing multiple…
Protein levels in CSF may help diagnose primary progressive MS
The level of proteins called kappa free light chains in the cerebrospinal fluid (CSF) — the liquid that surrounds the…
$24M in financing to advance treatments to protect myelin sheath
Myrobalan Therapeutics has secured $24 million in series A financing to support the development of oral medications for…
Compassion-focused therapy eases thoughts about suicide, pain
Engaging in online sessions of compassion-focused therapy, which works toward getting people to become more compassionate about themselves, may help…
Foralumab nasal spray shown to ease fatigue in nonactive SPMS
Six of eight patients with nonactive secondary progressive multiple sclerosis (SPMS) being treated with foralumab nasal spray —…