How Stem Cell Transplant Can ‘Reset’ Immune System in MS: Study
Following an autologous hematopoietic stem cell transplant (aHSCT) in people with multiple sclerosis (MS), the population of “naïve” T-cells…
Articles by Marisa Wexler, MS
Rituximab Doses for MS Might Be Best Timed By Measuring B-cells
Timing doses of rituximab by measuring B-cell counts is a more tailored approach to treatment, and it effectively reduces relapses and…
Dietary Changes Can Help Ease Fatigue, Improve Quality of Life
Dietary interventions may help ease fatigue and improve quality of life in people with multiple sclerosis (MS), although it…
Measuring Growth of Lesions in MS Better Predicts Disability Progression
Measuring how lesions get bigger over time in multiple sclerosis (MS) can predict long-term disability progression more accurately…
Life Expectancy Declines Linked to More Severe MS Disability in Study
Multiple sclerosis (MS) patients with minimal to moderate disability live about 30 additional years after their diagnosis, but life…
Risk of MS Activity After DMT Stop Greater With RRMS, Younger Age
Note: This story was updated Oct. 31, 2022, to correct that in the six months after treatment discontinuation, relapses were…
Trethera Awarded $1.6M to Develop TRE-515 as Optic Neuritis Treatment
Trethera has been awarded a $1.6 million grant to further develop TRE-515 as a potential treatment for optic neuritis…
Recurrent MS Disability Progression Measures May Aid Trial Efficiency
Measuring disability progression every time it occurs, rather than just tracking whether it occurs, could improve the statistical power of…
SYK Protein Needed for Microglial Cells to Clear Molecular Debris
A protein called spleen tyrosine kinase (SYK) is critical for microglia, the brain’s immune cells, to clear the toxic debris…
MS Therapy EHP-101 Boosts Blood Vessel Growth, Targets Inflammation
EHP-101, an experimental treatment being clinically tested for multiple sclerosis (MS), activates a cellular signaling pathway that promotes blood…
New Gait Analysis Tool Found to Correctly ID MS Patients in Videos
A new tool that analyzes gait, or walking patterns, of people on a treadmill — using video recordings from a…
Partnership Aims at Cell Therapy Targeting Epstein-Barr Virus in MS
NexImmune is working with the National Institute of Neurological Disorders and Stroke (NINDS) to develop cell therapies for…
Passive Health Tracking Can Predict Changes in MS, Study Says
Data passively collected by smartphone apps and fitness trackers can be used to accurately predict the risk of depression, severe…
Tecfidera Works Better Than Avonex to Ease MS in Children in Trial
Among children and adolescents with multiple sclerosis (MS), treatment with Tecfidera (dimethyl fumarate) resulted in less disease activity…
PET Tracer for Myelin Loss Shows Good Safety in 1st-in-human Study
A novel tracer designed to detect myelin loss in PET scans — imaging tests that use a radioactive substance, called…
Direct Electrical Stimulation of Brain Found to Ease MS Spasticity
Electrical stimulation of the brain through electrodes placed on the scalp may ease some measures of spasticity for people with…
Stem Cell Transplant May Halt Nerve Fiber Damage in RRMS: Study
Autologous hematopoietic stem cell transplant (aHSCT) reduces markers of nerve fiber and myelin damage in people with relapsing-remitting…
Guar Gum, Type of Dietary Fiber, Eases MS Severity in Mouse Model
Guar gum, a type of dietary fiber that can be taken as a supplement, lessened inflammation and disease severity in…
Quick MRI Method May Reliably Detect Myelin Repair in People
A quick MRI-based method called SyMRI may be useful in future clinical trials to test experimental myelin-repairing therapies in diseases…
Study Supports MS Disability Test Score as Outcome Measure in Trials
The Overall Disability Response Score, a combination of three different assessments of disability, could be used to more accurately evaluate…
AI Tool Aims to Make Progressive MS Trials More Effective for Patients
A new machine learning tool could help make clinical trials for progressive forms of multiple sclerosis (MS) more efficient…
Dual Cognitive, Motor Tasks More Difficult Even in Early MS Stages
Even in early stages of disease, people with multiple sclerosis (MS) commonly experience more difficulties performing cognitive and motor…
Pregnancy Risks Not Likely to Rise With Early DMT Use, Study Finds
The rates of pregnancy complications are not higher in women with multiple sclerosis (MS) who were using disease-modifying therapies…
Survival Much Higher for Patients Who Take DMTs as Directed: Study
The likelihood of survival is about 7.5 times higher for people with multiple sclerosis (MS) who take their disease-modifying…
Robot-assisted Training for Arms Well-received by MS Patients
A robot-assisted training program that uses game-like activities to improve upper limb function was met with high satisfaction and enjoyment…
GA Depot Reduces Relapse Rates in Phase 3 Clinical Trial
Treatment with GA Depot, an experimental long-acting form of glatiramer acetate that requires less frequent dosing than approved formulations,…
Thalamic Atrophy Moderates Ties Between Fitness, Cognition: Study
In people with multiple sclerosis (MS) who show atrophy in a brain region called the thalamus, aerobic fitness is…
Gut Bacteria Are Altered in MS, Linked to Disease Progression
The composition of bacteria in the gut is altered in multiple sclerosis (MS) patients compared with healthy people in…
NurOwn Found Safe, Shows Promise in Phase 2 Trial for Progressive MS
NurOwn, a stem cell therapy being developed by BrainStorm Cell Therapeutics, showed a good safety profile among people with progressive…
Study Supports Approved MS Dosage of Ponvory With No Adjustments
The approved dosage of the multiple sclerosis (MS) therapy Ponvory (ponesimod) — 20 mg taken by mouth once…