Marta Figueiredo, PhD, science writer —

Marta holds a biology degree, a master’s in evolutionary and developmental biology, and a PhD in biomedical sciences from the University of Lisbon, Portugal. She was awarded a research scholarship and a PhD scholarship, and her research focused on the role of several signaling pathways in thymus and parathyroid glands embryonic development. She also previously worked as an assistant professor of an annual one-week embryology course at the University of Lisbon’s Faculty of Medicine.

Articles by Marta Figueiredo

Delayed Ocrevus Infusion May Increase MRI-based RRMS Risk

An extended interval between maintenance doses of Ocrevus (ocrelizumab) may increase the risk of MRI-based disease activity in people with relapsing-remitting multiple sclerosis (RRMS), according to a real-world, multicenter study in Italy. In fact, an extended interval dosing (by one month or longer) was associated with a fivefold higher risk…

TRE-515 Appears to Block Immune Cell Attacks in Mouse Study

An experimental oral therapy called TRE-515 significantly reduced disease severity and the growth of the abnormal immune cells that drive multiple sclerosis (MS) in two mouse models of the disease, a study found. Notably, the efficacy of Trethera Corp.’s potential treatment, administered either in a preventive or therapeutic…

Study Uncovers How Interferon-beta May Be Helping to Treat MS

Researchers have discovered how interferon-beta, a common treatment for multiple sclerosis (MS), may be effective for people with the disease. Specifically, they found that red blood cells from MS patients have an unusually high ability to bind molecules that contribute to disease-related impairments in neuronal health and myelin repair,…

CNM-Au8 Lessens Vision Problems in RRMS Patients in Phase 2 Trial

CNM-Au8, Clene Nanomedicine’s experimental oral therapy, safely and effectively improves vision and neurological function in adults with stable relapsing-remitting multiple sclerosis (RRMS) and disease-related visual impairment. Those are the findings of the VISIONARY-MS Phase 2 clinical trial (NCT03536559), a proof-of-concept study that investigated CNM-Au8 in people with…

Calyx, Qynapse to Expand Use of Neuroimaging AI Tools

Calyx and Qynapse have joined forces to expand the use of artificial intelligence (AI)-based neuroimaging tools in clinical trials of treatment candidates for conditions affecting the central nervous system (CNS), or the brain and spinal cord. This is expected to help advance therapy development for multiple sclerosis…

Higher COVID-19 Risk Tied to 2 MS Therapies, Even With Vaccination

Fully vaccinated multiple sclerosis (MS) patients who are treated with Ocrevus (ocrelizumab) or Gilenya (fingolimod) have a significantly higher risk of COVID-19 infection than those given other immunosuppressive therapies, according to a study in Italy. Called breakthrough infections, these post-vaccination cases of SARS-CoV-2 — the virus that causes…

NICE Updates Its Guidelines for MS Management

The National Institute for Health and Care Excellence (NICE) in England has updated its guidelines for the diagnosis and management of adults with multiple sclerosis (MS). Called Multiple sclerosis in adults: management, the new guidelines update and replace the 2014 recommendations and are meant to be followed by…

PoNS Device Improves Walking Skills Early On, New Data Show

Using the portable neuromodulation stimulator (PoNS) device during a targeted exercise program significantly improves walking skills in people with multiple sclerosis (MS), according to recent real-word data. Notably, significant improvements were observed from the second week onward, and more than half of the 42 patients patients experienced clinically meaningful gains…

Lyvispah, Dissolvable Form of Baclofen, Now Available in US

Lyvispah — a dissolvable granular formulation of baclofen — is now commercially available in the U.S. for adults and adolescents, 12 and older, with spasticity associated with multiple sclerosis (MS) and other spinal cord disorders. In people with MS, the strawberry-flavored formulation is particularly suitable to ease flexor…

Mayzent and Kesimpta Gaining Ground as MS Treatments in Canada

Novartis’ Mayzent (siponimod) and Kesimpta (ofatumumab) are gaining ground among multiple sclerosis (MS) therapies in Canada, according to the latest Spherix Global Insights’ report. “Following an eventful 2021 that included the launch of two new brands — Novartis’ Kesimpta and BMS’ Zeposia — and generic versions of Biogen’s…

High Adherence to Rebif Seen With RebiSmart Use, Chats With Doctor

Regular feedback from doctors about dosing data and health status is associated with high and sustained treatment adherence to Rebif (interferon beta-1a) among multiple sclerosis (MS) patients using the RebiSmart autoinjector, a two-year observational study shows. This study’s level of treatment adherence — 97.9% — was comparable or superior to the…

Progressive MS, Degree of Disability Increase Infection Risk

People with progressive forms of multiple sclerosis (MS) and those with greater MS-related disability have a significantly greater risk of serious infections relative to people without the disease, according to a population-based study in Sweden. Notably, these associations were observed regardless of the use of disease-modifying therapies, many…

Biogen, MedRhythms Working on Music Therapy for MS Gait Issues

Biogen has entered a licensing agreement to develop and potentially commercialize MedRhythms‘ investigational music-based digital therapy, MR-004, designed to help make walking easier for people with multiple sclerosis (MS). The partnership combines Biogen’s leadership and expertise in MS with MedRhythms’ digital therapeutics platform that uses sensors, algorithms, and music…

B-cell-depleting Therapies May Increase Risk of Psoriasis

Reports of psoriasis — an autoimmune skin disease that shares some biological processes with multiple sclerosis (MS) — are disproportionally high among MS patients on therapies that deplete B-cells, according to a U.S. study based on patient adverse event data. Conversely, patients on Tysabri (natalizumab), glatiramer acetate (sold…

Survey Results Show Impact of MS in All Aspects of Life

Multiple sclerosis (MS) affects all aspects of life, from physical and mental health to relationships, and from work and finances to hobbies and holidays, according to results from an online survey conducted by the U.K.’s MS Trust. Most respondents said they wanted more support to manage their fatigue, improve…

New Imaging Techniques May Aid MS Diagnosis, Management

Physician-researchers at Cedars-Sinai Medical Center, in California, are developing brain and eye imaging techniques to improve the diagnosis and management of multiple sclerosis (MS). MS is characterized by the progressive loss of myelin, the fatty protective sheath around nerve fibers, in the brain and spinal cord due to abnormal…

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